Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   DP112_RS03495 Genome accession   NZ_CP030125
Coordinates   682232..684469 (+) Length   745 a.a.
NCBI ID   WP_114866356.1    Uniprot ID   -
Organism   Streptococcus suis strain HA1003     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 677232..689469
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP112_RS03475 (DP112_03475) - 677978..678763 (-) 786 WP_024382740.1 ABC transporter ATP-binding protein -
  DP112_RS03480 (DP112_03480) - 678915..680360 (-) 1446 WP_114866353.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  DP112_RS03485 (DP112_03485) - 680772..681518 (+) 747 WP_114866354.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  DP112_RS03490 (DP112_03490) - 681586..682248 (+) 663 WP_114866355.1 helix-hairpin-helix domain-containing protein -
  DP112_RS03495 (DP112_03495) comEC/celB 682232..684469 (+) 2238 WP_114866356.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 83692.59 Da        Isoelectric Point: 7.5872

>NTDB_id=299479 DP112_RS03495 WP_114866356.1 682232..684469(+) (comEC/celB) [Streptococcus suis strain HA1003]
MSRSIKLPCQPIHLAVLAVVAYFAVHSFSILTMGLLSLLLVVFGFRQGKAVFIRTLPLLALCGLFFGCQKVQWERAAQSA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQFFYKLASQEEQAYFQKLTGLVQLEVEAEVSLPAGQRNFKGFDYRAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSNWRRQALVYIKTNFPAPMSHYMTGLLFGDLDSEFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVNKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLVL
PRFPLTAGGVLTFTYAFLLMVFDFEDLGQVKKAAVESLSISLGILPVLMSFFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPVVKLTWVNGFFVFMEKIIVWVADLGLRPWILGKPSGLVLLLLLVSLFLLYDFHRKKKWLLGLSLVLALLFFTTK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSREANAERTLIPYLHSRGVDRIDSLVLTHTDAD
HVGDVLEVAKQVQIGRIYVSPGSLTVPDFVATLKEINVPVDVVAVGDRLPIFDSYLGVLYPDGTGDGGNNDSVVLYGRLL
ETNFLFTGDLEQGELDLIKTYPQLPVDVLKAGHHGSQGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWKEWMIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=299479 DP112_RS03495 WP_114866356.1 682232..684469(+) (comEC/celB) [Streptococcus suis strain HA1003]
ATGTCACGGTCGATTAAACTCCCCTGCCAGCCCATTCACCTGGCAGTCTTGGCGGTGGTGGCCTACTTTGCAGTCCATTC
TTTTTCCATCTTGACAATGGGCCTGCTAAGTCTGTTACTAGTTGTCTTTGGGTTTCGGCAAGGTAAGGCAGTTTTCATCA
GAACGCTGCCGCTTCTAGCCCTGTGCGGTCTGTTTTTCGGATGCCAGAAGGTCCAATGGGAGCGGGCAGCCCAGTCAGCC
CCAGAACAAGTGACGACTGTGCAGGTCATTCCTGATACCATTGAAGTCAACGGGGACAGCTTGTCTTTTCGAGGTCGGGC
TGATGGACAAACCTATCAGTTTTTCTACAAATTAGCCAGTCAGGAGGAGCAGGCTTATTTTCAAAAGTTGACAGGTCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGCTTTGACTATCGGGCCTATCTG
AAAACACAGGGCATCTATCGGACAGTCAAGCTAACGGCGATTAAGAAGATTGTCCCTGTCCAGTCTTGGAATGTTTTTGA
CTGGCTGTCAAACTGGCGGAGGCAGGCCTTGGTCTATATCAAAACCAATTTTCCAGCACCCATGAGCCACTATATGACAG
GACTCTTGTTTGGGGACTTGGACAGTGAGTTTGACCAGATGAGTGACCTCTATTCCAGTCTGGGTATCATTCATCTTTTC
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGGTGGATCTTGTTGCGGTTGGGCTTGACCAAGGAAAC
GGTGAATAAATTGCAGATTCCCTTTTCCCTGGTCTATGCTGGTTTGACAGGCTTTTCGGTGTCAGTAGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTTGGTCTGAGGAAGCTGGATAATTTTGCGGTGACAGTCTTTGTCTGCCTGCTGGTGCTG
CCCCGATTTCCACTGACAGCAGGAGGAGTGCTGACTTTTACATATGCATTCTTGCTTATGGTCTTTGATTTTGAGGACTT
GGGGCAGGTTAAAAAGGCTGCGGTGGAGAGTCTCAGTATTTCGCTGGGGATTCTACCTGTGCTCATGTCCTTTTTCTATG
CCTTTCAGCCCTTGTCTATTCTCTTGACATTTGTCTTTTCCTTTGTCTTTGATGTCCTGCTTTTGCCAGGTTTGTCAGTC
ATTTTTCTCTTGTCGCCAGTTGTCAAGCTGACTTGGGTCAACGGATTTTTTGTCTTTATGGAGAAAATCATTGTCTGGGT
GGCAGATTTGGGATTGCGACCTTGGATACTGGGTAAGCCGTCTGGGCTGGTCCTCCTGCTTTTGCTGGTCAGCCTCTTCT
TACTCTACGATTTCCACAGGAAGAAAAAATGGCTTCTAGGACTAAGCCTGGTCCTCGCTCTGCTATTTTTCACGACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCTTGATTGATGTGGGCGGACGGGTCGATTTTGCAGCCAAGGAAGCTTGGCAGGAGCGGTCTCGGGAGGCAAATGCAG
AGCGAACCTTGATCCCTTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTCCTGACCCATACCGACGCTGAC
CATGTGGGCGATGTGTTGGAAGTGGCGAAGCAGGTCCAGATTGGTCGGATTTACGTGTCGCCAGGAAGCCTGACGGTGCC
TGACTTTGTAGCCACCTTGAAAGAAATCAATGTCCCTGTTGATGTGGTGGCGGTGGGCGACCGCTTGCCGATTTTTGACT
CTTATCTGGGGGTCCTCTATCCAGACGGGACGGGTGACGGTGGCAATAATGACTCTGTTGTTCTTTACGGTCGTTTGCTG
GAAACCAATTTTCTCTTCACAGGTGACTTGGAGCAGGGGGAGTTGGACTTGATTAAAACCTATCCGCAGCTACCTGTTGA
TGTCCTCAAAGCTGGTCACCACGGCTCCCAAGGTTCTTCCTATCCTGAATTTCTAGACCATATCGGAGCCAAGATTGCCC
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCACCCTCACCAAGAAACCTTGGACCGCTTTGACAGTCGAAATATCCAA
GTCTATCGCACCGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAAAGAGTGGATGATTGAAACGGTGAGGGAGTAG

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(29-175)

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Competence protein (Competence)

(215-460)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

53.619

100

0.537
  comEC/celB Streptococcus mitis NCTC 12261

52.688

99.866

0.526
  comEC/celB Streptococcus pneumoniae TIGR4

51.812

100

0.518
  comEC/celB Streptococcus pneumoniae Rx1

51.544

100

0.515
  comEC/celB Streptococcus pneumoniae D39

51.544

100

0.515
  comEC/celB Streptococcus pneumoniae R6

51.544

100

0.515
  comEC Lactococcus lactis subsp. cremoris KW2

47.861

100

0.481

Multiple sequence alignment