Detailed information NTG0299435

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: DP111_RS06460
• Genome accession: NZ_CP030124
• Coordinates: 1264928..1265869 (-)
• Length: 313 a.a.
• NCBI ID: WP_024381435.1
• Uniprot ID: A0A075SIN6
• Organism: Streptococcus suis strain SH1510
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1259928..1270869

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DP111_RS06435 (DP111_06435)	prsA	1260033..1261034 (-)	1002	WP_024394667.1	peptidylprolyl isomerase PrsA	-
DP111_RS06440 (DP111_06440)	-	1261095..1261814 (-)	720	WP_043032894.1	O-methyltransferase	-
DP111_RS06445 (DP111_06445)	-	1261889..1262437 (-)	549	WP_002938103.1	DUF6630 family protein	-
DP111_RS06450 (DP111_06450)	-	1262453..1262893 (-)	441	WP_024394669.1	hypothetical protein	-
DP111_RS06455 (DP111_06455)	pepF	1262895..1264697 (-)	1803	WP_024381434.1	oligoendopeptidase F	Regulator
DP111_RS06460 (DP111_06460)	coiA	1264928..1265869 (-)	942	WP_024381435.1	competence protein CoiA family protein	Machinery gene
DP111_RS06465 (DP111_06465)	metG	1265930..1267933 (-)	2004	WP_044675531.1	methionine--tRNA ligase	-
DP111_RS06470 (DP111_06470)	-	1268090..1268683 (+)	594	WP_024394673.1	DUF1361 domain-containing protein	-
DP111_RS06480 (DP111_06480)	-	1268983..1270020 (+)	1038	WP_024394674.1	3-deoxy-7-phosphoheptulonate synthase	-

Sequence

Protein

• Length: 313 a.a.
• Molecular weight: 36249.85 Da
• Isoelectric Point: 8.0997

>NTDB_id=299435 DP111_RS06460 WP_024381435.1 1264928..1265869(-) (coiA) [Streptococcus suis strain SH1510]
MLVALDEDGQVFNVLENPAPQGRYSCPGCGGLVRYKSGKVLRSHFAHVTLRDCHYFSENESAQHLSLKSCLYSWLINAEQ
VELEKCLPSIGQVADLFVNNSLALEVQCSSLPISRLQLRTQAYHEAGFQVLWLLGKGLWIKERLSKLHKQFLSFSMNMGF
HLWELDDEKKELRLRYLIHEDLRGKVHCLTKVFPFGEGNLLDILRLPFAKQALSHLTCPLDRALPRYIAQQLYYKSPNWL
ALQAESYSRGENLLTKTAEEWYPHIRLPRSAIGFAQIQKDLTLVYQDFDQYYGNIEDKQKQVLYPPIIYRKPM

Nucleotide

• Length: 942 bp

>NTDB_id=299435 DP111_RS06460 WP_024381435.1 1264928..1265869(-) (coiA) [Streptococcus suis strain SH1510]
ATGTTAGTTGCACTTGATGAAGATGGACAAGTTTTTAATGTCTTGGAAAATCCTGCGCCGCAAGGTCGCTATTCTTGTCC
AGGTTGTGGAGGACTGGTCCGATACAAATCCGGAAAAGTTCTGCGTTCGCACTTTGCCCATGTAACCCTGCGGGACTGCC
ACTATTTTTCTGAGAATGAGTCAGCCCAGCATCTGTCACTTAAGTCTTGTCTGTACAGTTGGTTAATCAATGCCGAACAA
GTTGAACTTGAAAAATGCCTGCCTAGTATAGGGCAGGTCGCTGATTTATTTGTTAATAATAGTCTAGCTTTGGAAGTCCA
ATGTTCCAGTCTGCCCATTTCTCGTTTGCAGCTGAGGACGCAAGCCTATCATGAAGCTGGTTTTCAGGTTCTCTGGCTGT
TGGGAAAAGGCCTATGGATAAAAGAAAGATTAAGTAAATTACACAAGCAATTTCTCTCTTTTAGTATGAACATGGGTTTT
CACCTCTGGGAATTGGATGATGAGAAAAAAGAATTGCGTCTTCGTTACCTTATTCACGAAGACTTACGAGGTAAGGTCCA
CTGTCTGACAAAGGTTTTTCCATTTGGCGAGGGAAATTTATTGGACATCTTGCGTCTGCCATTTGCCAAGCAAGCTTTAT
CGCATCTTACTTGCCCGTTAGATAGGGCTTTGCCTCGCTACATTGCTCAACAGCTTTATTACAAATCCCCCAATTGGTTA
GCCCTGCAGGCAGAGTCTTATAGCCGAGGGGAGAATTTGCTGACAAAGACGGCAGAAGAATGGTATCCCCACATCCGTCT
ACCCCGCTCTGCCATTGGCTTTGCCCAAATACAAAAAGATTTAACCCTAGTTTATCAGGATTTTGACCAGTATTACGGCA
ATATTGAAGACAAGCAGAAACAGGTTCTATATCCACCTATAATTTATAGAAAACCAATGTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (21-221)

3D structure

• AlphaFold DB: A0A075SIN6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	52.564	99.681	0.524
coiA	Streptococcus pneumoniae TIGR4	50.641	99.681	0.505
coiA	Streptococcus pneumoniae Rx1	50.641	99.681	0.505
coiA	Streptococcus pneumoniae D39	50.641	99.681	0.505
coiA	Streptococcus pneumoniae R6	50.641	99.681	0.505
coiA	Lactococcus lactis subsp. cremoris KW2	41.875	100	0.428