Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   A7J09_RS10100 Genome accession   NZ_CP030015
Coordinates   2090299..2091591 (-) Length   430 a.a.
NCBI ID   WP_029178438.1    Uniprot ID   -
Organism   Streptococcus suis strain ISU2812     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2085299..2096591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J09_RS10090 (A7J09_10290) hpf 2089021..2089563 (-) 543 WP_014637536.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  A7J09_RS10095 (A7J09_10295) comFC/cflB 2089641..2090306 (-) 666 WP_002941737.1 ComF family protein Machinery gene
  A7J09_RS10100 (A7J09_10300) comFA/cflA 2090299..2091591 (-) 1293 WP_029178438.1 DEAD/DEAH box helicase Machinery gene
  A7J09_RS10105 (A7J09_10305) - 2091648..2092280 (+) 633 WP_024394374.1 YigZ family protein -
  A7J09_RS10110 (A7J09_10310) cysK 2092370..2093296 (+) 927 WP_029178437.1 cysteine synthase A -
  A7J09_RS10115 (A7J09_10315) - 2093322..2093693 (-) 372 WP_024394815.1 S1 RNA-binding domain-containing protein -
  A7J09_RS10120 (A7J09_10320) - 2093695..2095095 (-) 1401 WP_024394814.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  A7J09_RS10125 (A7J09_10325) - 2095145..2095786 (-) 642 WP_024394813.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48919.42 Da        Isoelectric Point: 9.0315

>NTDB_id=298277 A7J09_RS10100 WP_029178438.1 2090299..2091591(-) (comFA/cflA) [Streptococcus suis strain ISU2812]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVKNNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYQAADNAVKEDGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRTSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTSSSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=298277 A7J09_RS10100 WP_029178438.1 2090299..2091591(-) (comFA/cflA) [Streptococcus suis strain ISU2812]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GAAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCGGTTCCAATTAGTTTACTGCATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCAAGCAGCAGATAATGCGGTCAAGGAAGACGGAGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACGGGCAAATTAAGCCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAATCCGCTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAACGTCGGGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACCTCATCCAGTCTAGTGCAGATTGCAGGTCGGGTTGGTAGGAGTATGGAACGTCCGACTGGT
TTACTCCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(91-235)

Helicase conserved C-terminal domain (Helicase_C)

(291-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.053

100

0.672
  comFA/cflA Streptococcus pneumoniae Rx1

66.357

100

0.665
  comFA/cflA Streptococcus pneumoniae D39

66.357

100

0.665
  comFA/cflA Streptococcus pneumoniae R6

66.357

100

0.665
  comFA/cflA Streptococcus pneumoniae TIGR4

66.357

100

0.665
  comFA/cflA Streptococcus mitis SK321

65.893

100

0.66
  comFA Lactococcus lactis subsp. cremoris KW2

53.904

92.326

0.498
  comFA Latilactobacillus sakei subsp. sakei 23K

37.819

100

0.379
  comFA Bacillus subtilis subsp. subtilis str. 168

37.349

96.512

0.36

Multiple sequence alignment