Detailed information NTG0298275

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: A7J09_RS09435
• Genome accession: NZ_CP030015
• Coordinates: 1957870..1960107 (-)
• Length: 745 a.a.
• NCBI ID: WP_029178644.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ISU2812
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1952870..1965107

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7J09_RS09410 (A7J09_09610)	-	1953374..1954629 (+)	1256	WP_172411187.1	ISL3 family transposase	-
A7J09_RS09415 (A7J09_09615)	-	1954702..1955973 (-)	1272	WP_002935355.1	toxic anion resistance protein	-
A7J09_RS09420 (A7J09_09620)	-	1955979..1956806 (-)	828	WP_002935354.1	hypothetical protein	-
A7J09_RS09425 (A7J09_09625)	-	1956900..1957556 (-)	657	WP_002935353.1	CBS domain-containing protein	-
A7J09_RS09430	-	1957739..1957861 (-)	123	Protein_1833	IS982 family transposase	-
A7J09_RS09435 (A7J09_09630)	comEC/celB	1957870..1960107 (-)	2238	WP_029178644.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
A7J09_RS09440 (A7J09_09635)	-	1960091..1960753 (-)	663	WP_029178643.1	helix-hairpin-helix domain-containing protein	-
A7J09_RS09445 (A7J09_09640)	-	1960820..1961566 (-)	747	WP_029174959.1	lysophospholipid acyltransferase family protein	-
A7J09_RS09450 (A7J09_09645)	-	1961713..1963158 (+)	1446	WP_029174960.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
A7J09_RS09455 (A7J09_09650)	-	1963512..1964297 (+)	786	WP_014636900.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 83913.59 Da
• Isoelectric Point: 6.6728

>NTDB_id=298275 A7J09_RS09435 WP_029178644.1 1957870..1960107(-) (comEC/celB) [Streptococcus suis strain ISU2812]
MSRSIKLPCQPIHLAVLAVAAYFAVHSFSLLTMGLLSLVLAVFGVRQGKTVFLKTLLLLALCGLFFGYQKVQWERADQSA
PEQVTTVQVIPDTIEVNGDSLSFRGRSDGQTYQVFYKLASQEEQTYFQELTDLVQLEVEAEVSLPAGQRNFNGFDYQAYL
KTQGIYRTVKISAIKKIVPIQSWNVFDLLSSWRRQALVYIKTNFPAPMSHYMTGLLFGELDSEFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRVGLTKETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGILTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSTLVKITWVNGFFVLMEKIIVWVADLGFRPWILGKPSGVILVLLLVSLFLLYDFHRKKKWLLGLSMVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEEWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIYVSPGSLTVPDFVATLKEINVPVHVVAVGDRLPIFDFYLEVLYPDGTGDGGNNDSVVLYGRLL
ETNFLFTGDLEQGELDLIEAYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=298275 A7J09_RS09435 WP_029178644.1 1957870..1960107(-) (comEC/celB) [Streptococcus suis strain ISU2812]
ATGTCACGGTCGATTAAGCTCCCCTGCCAGCCCATCCATCTGGCAGTCTTGGCGGTGGCGGCCTACTTTGCAGTCCACTC
TTTTTCCCTGTTGACAATGGGCCTACTCAGTTTGGTGTTAGCTGTCTTTGGTGTTCGGCAAGGTAAGACGGTTTTCCTCA
AAACGCTGCTGCTTTTAGCTCTATGTGGCTTGTTTTTCGGCTACCAAAAGGTCCAATGGGAGCGGGCAGACCAGTCAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACGATTGAAGTCAACGGGGACAGCCTGTCTTTTCGTGGTCGGTC
TGACGGACAAACCTATCAGGTTTTCTACAAATTAGCCAGTCAGGAGGAGCAGACTTATTTTCAAGAGCTAACAGATTTGG
TCCAGCTTGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAACGGCTTTGACTACCAAGCCTATCTG
AAAACGCAGGGAATTTATCGGACAGTTAAGATTTCTGCGATTAAGAAGATTGTCCCTATCCAGTCTTGGAATGTTTTTGA
CTTGCTATCAAGCTGGCGGAGGCAGGCCTTGGTCTATATCAAAACCAATTTTCCAGCACCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGAGTTGGATAGTGAGTTTGACCAGATGAGTGACCTCTATTCTAGTCTGGGTATCATTCATCTCTTT
GCCCTGTCTGGCATGCAGGTTGGATTTTTCATCGACAAATTTCGTTGGATTTTGTTGCGTGTGGGTCTGACCAAGGAAAC
TGTGGATAAATTACAAATTCCCTTTTCTCTTGTCTATGCTGGTTTGACAGGTTTTTCTGTGTCAGTGGTGCGGTCTTTGG
TTCAGAAAATATTGGGCAATCTGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGCTGATTCTG
CCCCGATTTTTACTGACAGCAGGAGGTATATTGACCTTTACCTATGCTTTCTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCACTGGGAATTTTGCCGGTGCTTATGACCTATTTCTATG
CCTTTCAGCCTTTGTCTATCCTCTTGACCTTTGTCTTTTCCTTTGTCTTTGATGTTCTGCTTTTGCCAGGATTGTCGGTC
ATTTTTCTTCTATCGACCTTGGTCAAGATTACCTGGGTCAACGGATTTTTTGTCTTGATGGAAAAAATCATTGTCTGGGT
AGCGGATTTGGGCTTTCGGCCTTGGATATTGGGCAAGCCGTCTGGGGTAATTCTTGTTCTTTTGCTGGTCAGCCTTTTCT
TGCTCTATGATTTCCACAGGAAAAAGAAATGGCTCTTAGGACTGAGCATGGTCCTTGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGTGGTCGGGTTGATTTTGCGGCTAAGGAGGAGTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCACAGTCGGGGCGTGGATAGGATTGATAGTCTAGTGCTGACCCACACCGACACAGAC
CATGTGGGCGATGTGCTAGAAGTGGCTAAGCAGGTACAAATTGGTCGAATTTACGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCGACTTTGAAAGAAATCAATGTCCCTGTTCATGTGGTGGCGGTAGGCGACCGCTTGCCGATTTTTGACT
TCTATCTGGAAGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCTGTTGTTCTTTACGGTCGCTTGCTG
GAAACTAACTTTCTCTTTACAGGAGATTTGGAGCAAGGGGAGTTGGACTTGATAGAAGCCTATCCCAACCTGCCTGTCGA
TGTCCTTAAAGCTGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTCTAGACCATATCGGAGCCAAGATTGCCC
TGGTATCAGCAGGAGAAAATAACCGCTACAAGCATCCCCATCAAGAAACCTTGGAACGATTTGATAGTCGGAATATCCAA
GTCTATCGTACCGACCAGCAAGGAGCCATTCGCTTTCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Competence protein (Competence) (215-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.189	99.329	0.538
comEC/celB	Streptococcus mitis NCTC 12261	53.469	98.658	0.528
comEC/celB	Streptococcus pneumoniae TIGR4	52.717	98.792	0.521
comEC/celB	Streptococcus pneumoniae Rx1	52.174	98.792	0.515
comEC/celB	Streptococcus pneumoniae D39	52.174	98.792	0.515
comEC/celB	Streptococcus pneumoniae R6	52.174	98.792	0.515
comEC	Lactococcus lactis subsp. cremoris KW2	48.327	100	0.485