Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   EQH16_RS00110 Genome accession   NZ_CP035264
Coordinates   21539..21775 (+) Length   78 a.a.
NCBI ID   WP_000939544.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901921     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 16539..26775
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH16_RS00100 (EQH16_00105) - 20274..20483 (+) 210 Protein_14 transposase -
  EQH16_RS00105 (EQH16_00110) - 20518..21273 (-) 756 Protein_15 transposase -
  EQH16_RS00110 (EQH16_00115) comW 21539..21775 (+) 237 WP_000939544.1 sigma(X)-activator ComW Regulator
  EQH16_RS00115 (EQH16_00120) - 22006..23292 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  EQH16_RS00120 (EQH16_00125) - 23534..24682 (-) 1149 WP_000876722.1 site-specific integrase -
  EQH16_RS00125 (EQH16_00130) - 25053..25460 (-) 408 WP_001173135.1 DUF4429 domain-containing protein -
  EQH16_RS00130 (EQH16_00135) - 25505..25888 (-) 384 WP_000136458.1 ImmA/IrrE family metallo-endopeptidase -
  EQH16_RS00135 (EQH16_00140) - 25901..26266 (-) 366 WP_000477680.1 helix-turn-helix domain-containing protein -
  EQH16_RS00140 (EQH16_00145) - 26553..26762 (+) 210 WP_000082680.1 helix-turn-helix transcriptional regulator -

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9667.10 Da        Isoelectric Point: 6.4701

>NTDB_id=297865 EQH16_RS00110 WP_000939544.1 21539..21775(+) (comW) [Streptococcus pneumoniae strain TVO_1901921]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=297865 EQH16_RS00110 WP_000939544.1 21539..21775(+) (comW) [Streptococcus pneumoniae strain TVO_1901921]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCATAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974

  comW Streptococcus pneumoniae D39

97.436

100

0.974

  comW Streptococcus pneumoniae R6

97.436

100

0.974

  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974

  comW Streptococcus mitis SK321

78.205

100

0.782

  comW Streptococcus mitis NCTC 12261

77.922

98.718

0.769