Detailed information NTG0297639

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: EQH18_RS01250
• Genome accession: NZ_CP035262
• Coordinates: 231239..232237 (+)
• Length: 332 a.a.
• NCBI ID: WP_001813535.1
• Uniprot ID: B2ISI4
• Organism: Streptococcus pneumoniae strain TVO_1901923
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 226239..237237

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH18_RS01230 (EQH18_01290)	leuS	226379..228880 (+)	2502	WP_000011784.1	leucine--tRNA ligase	-
EQH18_RS01235 (EQH18_01295)	-	229075..229770 (+)	696	WP_001144913.1	GNAT family N-acetyltransferase	-
EQH18_RS01240 (EQH18_01300)	-	229782..230198 (+)	417	WP_000628392.1	GNAT family N-acetyltransferase	-
EQH18_RS01245 (EQH18_01305)	-	231013..231105 (-)	93	WP_000970381.1	type I toxin-antitoxin system Fst family toxin	-
EQH18_RS01250 (EQH18_01310)	ruvB	231239..232237 (+)	999	WP_001813535.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
EQH18_RS01255 (EQH18_01315)	-	232218..232790 (+)	573	WP_001815451.1	nucleotidyltransferase family protein	-
EQH18_RS01260 (EQH18_01320)	-	233021..233779 (+)	759	WP_000466720.1	isoprenyl transferase	-
EQH18_RS01265 (EQH18_01325)	-	233788..234591 (+)	804	WP_000189866.1	phosphatidate cytidylyltransferase	-
EQH18_RS01270 (EQH18_01330)	eeP	234613..235872 (+)	1260	WP_000900660.1	RIP metalloprotease RseP	Regulator

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37271.70 Da
• Isoelectric Point: 4.5053

>NTDB_id=297639 EQH18_RS01250 WP_001813535.1 231239..232237(+) (ruvB) [Streptococcus pneumoniae strain TVO_1901923]
MSRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPVIEKAGDLVAILNELEPGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRVRDFAQIVGNGVID
DVITDKALTMLDVDHEGLDYVDQKILRTMIEMYGGGPVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRMATAK
AYEHLGYEYNEK

Nucleotide

• Length: 999 bp

>NTDB_id=297639 EQH18_RS01250 WP_001813535.1 231239..232237(+) (ruvB) [Streptococcus pneumoniae strain TVO_1901923]
ATGAGTAGAATTTTAGATAATGAGATAATGGGGGATGAGGAGTTAGTAGAACGCACGCTCCGTCCTCAGTATTTACGTGA
ATATATCGGACAGGATAAGGTCAAGGACCAGCTACAAATCTTTATTGAAGCTGCCAAAATGCGGGATGAAGCGCTGGATC
ATGTGCTCTTATTTGGCCCTCCAGGGCTTGGGAAAACAACCATGGCTTTTGTCATTGCCAATGAACTGGGAGTCAATCTC
AAGCAAACGTCTGGTCCTGTTATCGAAAAAGCGGGTGATTTGGTAGCGATTTTGAATGAGTTAGAGCCTGGAGATGTCCT
CTTTATTGACGAGATCCATCGTTTGCCAATGTCAGTGGAAGAGGTGCTTTATAGTGCTATGGAGGACTTCTACATAGATA
TTATGATTGGGGCTGGTGAGGGTAGTCGTAGTGTTCATTTGGAGTTACCACCTTTTACCTTGATTGGTGCGACGACTCGG
GCTGGTATGCTCTCAAATCCACTACGGGCACGTTTTGGGATTACAGGCCATATGGAGTATTATGCCCATGCTGACTTGAC
AGAAATTGTCGAGCGGACGGCAGATATTTTTGAGATGGAAATCACTCATGAGGCAGCATCTGAGTTGGCCCTACGTAGTC
GTGGGACCCCTCGTATTGCCAATCGTCTCCTCAAGCGCGTGCGCGATTTTGCCCAGATAGTGGGGAATGGGGTTATCGAT
GATGTTATTACCGATAAGGCTTTGACTATGCTGGATGTTGACCATGAAGGTTTGGACTATGTGGATCAAAAAATCCTTCG
CACCATGATTGAGATGTACGGTGGTGGCCCTGTCGGATTAGGAACTCTTTCTGTCAATATTGCCGAGGAGCGTGAGACTG
TAGAAGACATGTATGAGCCTTACTTGATTCAAAAAGGTTTTATCATGCGGACACGGTCTGGACGGATGGCGACTGCTAAG
GCATATGAGCATTTGGGGTATGAGTACAATGAAAAATAA

Domains

Predicted by InterProScan.

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

3D structure

• AlphaFold DB: B2ISI4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	98.494	100	0.985
ruvB	Streptococcus pneumoniae D39	98.494	100	0.985
ruvB	Streptococcus pneumoniae TIGR4	98.193	100	0.982
ruvB	Bacillus subtilis subsp. subtilis str. 168	60.429	98.193	0.593
ruvB	Helicobacter pylori 26695	50.774	97.289	0.494
ruvB	Synechocystis sp. PCC 6803	48.193	100	0.482