Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   SUB_RS06500 Genome accession   NC_012004
Coordinates   1286981..1287631 (+) Length   216 a.a.
NCBI ID   WP_012658774.1    Uniprot ID   B9DUW3
Organism   Streptococcus uberis 0140J     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1281981..1292631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUB_RS06475 (SUB1295) - 1282954..1283193 (-) 240 WP_012658769.1 DUF3165 family protein -
  SUB_RS06480 (SUB1296) typA 1283299..1285140 (-) 1842 WP_012658770.1 translational GTPase TypA -
  SUB_RS06485 (SUB1297) - 1285311..1285691 (-) 381 WP_012658771.1 rhodanese-like domain-containing protein -
  SUB_RS06490 (SUB1298) - 1285700..1286671 (-) 972 WP_012658772.1 ROK family glucokinase -
  SUB_RS06495 (SUB1299) - 1286661..1286879 (-) 219 WP_012658773.1 YqgQ family protein -
  SUB_RS06500 (SUB1300) cclA/cilC 1286981..1287631 (+) 651 WP_012658774.1 prepilin peptidase Machinery gene
  SUB_RS06505 (SUB1301) - 1287656..1289401 (-) 1746 WP_012658775.1 ABC transporter ATP-binding protein -
  SUB_RS06510 (SUB1302) - 1289388..1291136 (-) 1749 WP_012658776.1 ABC transporter ATP-binding protein -
  SUB_RS06515 (SUB1303) - 1291217..1291672 (-) 456 WP_012658777.1 VanZ family protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 24949.47 Da        Isoelectric Point: 8.2237

>NTDB_id=29692 SUB_RS06500 WP_012658774.1 1286981..1287631(+) (cclA/cilC) [Streptococcus uberis 0140J]
MIPILFFCLGASLGSFMGVIWDRFPENSIIWPPSHCDNCKHSLKAQQLIPIFSVLMTGFKCAFCKQRVSPVYSLIELVMG
LIFWCAQQHLFLSWIDVYMISISILLSLYDMKTQSYPFIIWIFSFMILLPFYEWNLLVFFFLLIALLCTIWPAVIGNGDL
LYLASIALVYDLKMTLWIIQIASILGLAFCLVQKKRKIPFLPFLSLTLLVLLCLKH

Nucleotide


Download         Length: 651 bp        

>NTDB_id=29692 SUB_RS06500 WP_012658774.1 1286981..1287631(+) (cclA/cilC) [Streptococcus uberis 0140J]
ATGATACCTATTTTATTTTTTTGTTTAGGAGCAAGTCTTGGTTCTTTTATGGGGGTTATTTGGGATAGGTTCCCTGAAAA
CTCAATTATTTGGCCGCCAAGTCATTGTGACAACTGTAAGCATTCACTAAAAGCACAGCAGTTGATACCTATTTTTTCTG
TCTTAATGACAGGCTTTAAATGTGCTTTTTGTAAGCAGCGGGTCTCTCCAGTTTATAGCTTGATTGAGTTAGTCATGGGT
CTCATCTTTTGGTGTGCCCAGCAACATCTTTTTTTATCATGGATAGATGTCTATATGATTTCCATTTCCATCCTTTTATC
ACTCTACGATATGAAGACACAATCTTACCCTTTTATAATCTGGATTTTTTCTTTTATGATACTTCTTCCTTTCTATGAAT
GGAACTTGCTCGTCTTCTTCTTTCTTTTGATAGCCTTACTATGCACCATTTGGCCAGCAGTTATCGGAAATGGAGATCTC
CTCTATTTAGCTAGCATAGCCTTAGTCTACGATCTGAAAATGACACTCTGGATTATCCAAATTGCTAGCATTTTAGGCTT
AGCCTTTTGTCTTGTCCAGAAAAAAAGAAAAATTCCTTTTTTACCCTTTTTAAGTCTTACTTTACTAGTCTTGCTATGTT
TGAAGCACTAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-86)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9DUW3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

40.376

98.611

0.398
  cclA/cilC Streptococcus mitis NCTC 12261

39.437

98.611

0.389
  cclA/cilC Streptococcus pneumoniae Rx1

38.967

98.611

0.384
  cclA/cilC Streptococcus pneumoniae D39

38.967

98.611

0.384
  cclA/cilC Streptococcus pneumoniae R6

38.967

98.611

0.384
  cclA/cilC Streptococcus pneumoniae TIGR4

39.423

96.296

0.38

Multiple sequence alignment