Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   EQH24_RS00105 Genome accession   NZ_CP035256
Coordinates   21282..21518 (+) Length   78 a.a.
NCBI ID   WP_000939545.1    Uniprot ID   A0A0H2ZMA7
Organism   Streptococcus pneumoniae strain TVO_1901930     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 16282..26518
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH24_RS00100 (EQH24_00100) - 20235..21016 (-) 782 Protein_14 transposase -
  EQH24_RS00105 (EQH24_00105) comW 21282..21518 (+) 237 WP_000939545.1 sigma(X)-activator ComW Regulator
  EQH24_RS00110 (EQH24_00110) - 21749..23035 (+) 1287 WP_023396065.1 adenylosuccinate synthase -
  EQH24_RS00115 (EQH24_00115) tadA 23236..23703 (+) 468 WP_000291870.1 tRNA adenosine(34) deaminase TadA -
  EQH24_RS00125 (EQH24_00125) - 23912..25054 (-) 1143 WP_000266837.1 site-specific integrase -
  EQH24_RS00130 (EQH24_00130) - 25173..25523 (-) 351 WP_001020945.1 hypothetical protein -
  EQH24_RS00135 (EQH24_00135) - 25537..25917 (-) 381 WP_000136430.1 ImmA/IrrE family metallo-endopeptidase -
  EQH24_RS00140 (EQH24_00140) - 25939..26295 (-) 357 WP_000153672.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9658.13 Da        Isoelectric Point: 6.7051

>NTDB_id=296906 EQH24_RS00105 WP_000939545.1 21282..21518(+) (comW) [Streptococcus pneumoniae strain TVO_1901930]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=296906 EQH24_RS00105 WP_000939545.1 21282..21518(+) (comW) [Streptococcus pneumoniae strain TVO_1901930]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTAAGATATGGCATTGGTTGTCGTAAGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZMA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

100

100

1
  comW Streptococcus pneumoniae D39

100

100

1
  comW Streptococcus pneumoniae R6

100

100

1
  comW Streptococcus pneumoniae TIGR4

100

100

1
  comW Streptococcus mitis SK321

75.641

100

0.756
  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744