Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   EQH26_RS00215 Genome accession   NZ_CP035254
Coordinates   35357..35593 (+) Length   78 a.a.
NCBI ID   WP_000939546.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901932     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 30357..40593
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH26_RS00205 (EQH26_00205) - 34050..34259 (+) 210 Protein_35 transposase -
  EQH26_RS00210 (EQH26_00210) - 34294..35091 (-) 798 Protein_36 transposase -
  EQH26_RS00215 (EQH26_00215) comW 35357..35593 (+) 237 WP_000939546.1 sigma(X)-activator ComW Regulator
  EQH26_RS00220 (EQH26_00220) - 35824..37110 (+) 1287 WP_001821607.1 adenylosuccinate synthase -
  EQH26_RS00225 (EQH26_00225) - 37374..38522 (-) 1149 WP_000876726.1 site-specific integrase -
  EQH26_RS00230 (EQH26_00230) - 38701..39624 (-) 924 WP_000122590.1 exonuclease domain-containing protein -
  EQH26_RS00235 (EQH26_00235) - 39637..40020 (-) 384 WP_000136455.1 ImmA/IrrE family metallo-endopeptidase -
  EQH26_RS00240 (EQH26_00240) - 40033..40395 (-) 363 WP_000466344.1 helix-turn-helix domain-containing protein -

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9686.14 Da        Isoelectric Point: 6.7051

>NTDB_id=296785 EQH26_RS00215 WP_000939546.1 35357..35593(+) (comW) [Streptococcus pneumoniae strain TVO_1901932]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=296785 EQH26_RS00215 WP_000939546.1 35357..35593(+) (comW) [Streptococcus pneumoniae strain TVO_1901932]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTACCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987

  comW Streptococcus pneumoniae D39

98.718

100

0.987

  comW Streptococcus pneumoniae R6

98.718

100

0.987

  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987

  comW Streptococcus mitis SK321

76.923

100

0.769

  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756