NTDB

Overview

Name	comR	Type	Regulator
Locus tag	EQH28_RS09750	Genome accession	NZ_CP035252
Coordinates	1900066..1900887 (-)	Length	273 a.a.
NCBI ID	WP_000904827.1	Uniprot ID	-
Organism	Streptococcus pneumoniae strain TVO_1901934
Function	activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1895066..1905887

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH28_RS09725 (EQH28_10280)	rsmA	1895291..1896163 (-)	873	WP_001216852.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
EQH28_RS09730 (EQH28_10285)	-	1896414..1896707 (-)	294	WP_000333255.1	hypothetical protein	-
EQH28_RS09735 (EQH28_10290)	-	1896700..1897341 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
EQH28_RS09740 (EQH28_10295)	-	1897343..1899373 (-)	2031	WP_000825244.1	bacteriocin-associated integral membrane family protein	-
EQH28_RS09745 (EQH28_10300)	-	1899450..1899746 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
EQH28_RS09750 (EQH28_10305)	comR	1900066..1900887 (-)	822	WP_000904827.1	XRE family transcriptional regulator	Regulator
EQH28_RS09755 (EQH28_10310)	rnmV	1900959..1901519 (-)	561	WP_000660019.1	ribonuclease M5	-
EQH28_RS09760 (EQH28_10315)	-	1901519..1902292 (-)	774	WP_000575601.1	TatD family hydrolase	-
EQH28_RS09765 (EQH28_10325)	-	1902597..1903568 (-)	972	Protein_1932	DUF1542 domain-containing protein	-
EQH28_RS09770 (EQH28_10330)	rpmH	1903774..1903908 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
EQH28_RS09775 (EQH28_10335)	-	1904316..1905269 (+)	954	WP_001155339.1	IS30-like element ISSpn8 family transposase	-

Sequence

Protein

Download Length: 273 a.a. Molecular weight: 32180.61 Da Isoelectric Point: 6.1110

                                >NTDB_id=296753 EQH28_RS09750 WP_000904827.1 1900066..1900887(-) (comR) [Streptococcus pneumoniae strain TVO_1901934]

MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI

LREPIYGKEEEYDKKEACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLLIRLFFYQMLIRKDLAKFINQIEKLML

FLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAES

FYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

Download Length: 822 bp

                                >NTDB_id=296753 EQH28_RS09750 WP_000904827.1 1900066..1900887(-) (comR) [Streptococcus pneumoniae strain TVO_1901934]

ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA

ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC

GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT

TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTATGATAAGAAAGAAGCGTGTTTGGATACTTCTAGAACTAGAAGGCC

TGAATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGT

TGATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTC

TTTCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTG

TCTTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATT

ATCAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCA

TTTTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGA

GGATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(7-59)

ComR tetratricopeptide (ComR_TPR)

(94-265)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comR	Streptococcus pyogenes MGAS8232	34.564	100	0.377
comR	Streptococcus mutans UA159	34.354	100	0.37
comR	Streptococcus suis P1/7	34.364	100	0.366
comR	Streptococcus suis 05ZYH33	34.364	100	0.366
comR	Streptococcus pyogenes MGAS315	33.333	100	0.366

Detailed information NTG0296753