Detailed information NTG0296629

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EQH29_RS09170
• Genome accession: NZ_CP035251
• Coordinates: 1831476..1832297 (-)
• Length: 273 a.a.
• NCBI ID: WP_000904827.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901935
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1826476..1837297

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH29_RS09145 (EQH29_09715)	rsmA	1826701..1827573 (-)	873	WP_001216852.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
EQH29_RS09150 (EQH29_09720)	-	1827824..1828117 (-)	294	WP_000333255.1	hypothetical protein	-
EQH29_RS09155 (EQH29_09725)	-	1828110..1828751 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
EQH29_RS09160 (EQH29_09730)	-	1828753..1830783 (-)	2031	WP_000825244.1	bacteriocin-associated integral membrane family protein	-
EQH29_RS09165 (EQH29_09735)	-	1830860..1831156 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
EQH29_RS09170 (EQH29_09740)	comR	1831476..1832297 (-)	822	WP_000904827.1	XRE family transcriptional regulator	Regulator
EQH29_RS09175 (EQH29_09745)	rnmV	1832369..1832929 (-)	561	WP_000660019.1	ribonuclease M5	-
EQH29_RS09180 (EQH29_09750)	-	1832929..1833702 (-)	774	WP_000575601.1	TatD family hydrolase	-
EQH29_RS09185 (EQH29_09760)	-	1834007..1834978 (-)	972	Protein_1816	DUF1542 domain-containing protein	-
EQH29_RS09190 (EQH29_09765)	rpmH	1835184..1835318 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
EQH29_RS09195 (EQH29_09770)	-	1835726..1836679 (+)	954	WP_001155339.1	IS30-like element ISSpn8 family transposase	-

Sequence

Protein

• Length: 273 a.a.
• Molecular weight: 32180.61 Da
• Isoelectric Point: 6.1110

>NTDB_id=296629 EQH29_RS09170 WP_000904827.1 1831476..1832297(-) (comR) [Streptococcus pneumoniae strain TVO_1901935]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLLIRLFFYQMLIRKDLAKFINQIEKLML
FLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAES
FYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 822 bp

>NTDB_id=296629 EQH29_RS09170 WP_000904827.1 1831476..1832297(-) (comR) [Streptococcus pneumoniae strain TVO_1901935]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTATGATAAGAAAGAAGCGTGTTTGGATACTTCTAGAACTAGAAGGCC
TGAATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGT
TGATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTC
TTTCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTG
TCTTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATT
ATCAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCA
TTTTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGA
GGATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (7-59)

• ComR tetratricopeptide (ComR_TPR) (94-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	34.564	100	0.377
comR	Streptococcus mutans UA159	34.354	100	0.37
comR	Streptococcus suis P1/7	34.364	100	0.366
comR	Streptococcus suis 05ZYH33	34.364	100	0.366
comR	Streptococcus pyogenes MGAS315	33.333	100	0.366