Detailed information NTG0295200

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EQH43_RS09375
• Genome accession: NZ_CP035237
• Coordinates: 1843740..1844639 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904848.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_Taiwan19F-14
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1838740..1849639

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH43_RS09355 (EQH43_09850)	rsmA	1839390..1840262 (-)	873	WP_001216856.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
EQH43_RS09360	-	1840513..1840806 (-)	294	Protein_1853	hypothetical protein	-
EQH43_RS09365 (EQH43_09855)	-	1840799..1841440 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
EQH43_RS09370 (EQH43_09860)	-	1841442..1843472 (-)	2031	WP_000825271.1	bacteriocin-associated integral membrane family protein	-
EQH43_RS09375 (EQH43_09865)	comR	1843740..1844639 (-)	900	WP_000904848.1	helix-turn-helix transcriptional regulator	Regulator
EQH43_RS09380 (EQH43_09870)	rnmV	1844711..1845271 (-)	561	WP_000660013.1	ribonuclease M5	-
EQH43_RS09385 (EQH43_09875)	-	1845271..1846044 (-)	774	WP_000575650.1	TatD family hydrolase	-
EQH43_RS09390 (EQH43_09885)	-	1846349..1847320 (-)	972	Protein_1859	DUF1542 domain-containing protein	-
EQH43_RS09395 (EQH43_09895)	rpmH	1847526..1847660 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
EQH43_RS09400 (EQH43_09900)	-	1847805..1849019 (-)	1215	WP_000666484.1	pyridoxal phosphate-dependent aminotransferase	-
EQH43_RS09405 (EQH43_09905)	-	1849175..1849467 (-)	293	Protein_1862	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35420.14 Da
• Isoelectric Point: 4.6674

>NTDB_id=295200 EQH43_RS09375 WP_000904848.1 1843740..1844639(-) (comR) [Streptococcus pneumoniae strain TVO_Taiwan19F-14]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEELMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=295200 EQH43_RS09375 WP_000904848.1 1843740..1844639(-) (comR) [Streptococcus pneumoniae strain TVO_Taiwan19F-14]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATATCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAGAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus pyogenes MGAS8232	36.577	99.666	0.365
comR	Streptococcus pyogenes MGAS315	36	100	0.361
comR	Streptococcus suis P1/7	37.113	97.324	0.361
comR	Streptococcus suis 05ZYH33	37.113	97.324	0.361