Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   CSC33_RS18805 Genome accession   NZ_CP029660
Coordinates   3929217..3930554 (+) Length   445 a.a.
NCBI ID   WP_003094694.1    Uniprot ID   A0A0H2ZG94
Organism   Pseudomonas aeruginosa strain AR_0446     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 3924217..3935554
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSC33_RS18780 (CSC33_3808) pgeF 3924360..3925088 (-) 729 WP_058179501.1 peptidoglycan editing factor PgeF -
  CSC33_RS18785 (CSC33_3809) rluD 3925085..3926047 (-) 963 WP_033972915.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  CSC33_RS18790 (CSC33_3810) - 3926193..3927218 (+) 1026 WP_033972916.1 outer membrane protein assembly factor BamD -
  CSC33_RS18795 (CSC33_3811) - 3927375..3927620 (+) 246 WP_003102591.1 PP0621 family protein -
  CSC33_RS18800 (CSC33_3812) pilS 3927610..3929202 (+) 1593 WP_039028118.1 two-component system sensor histidine kinase PilS Regulator
  CSC33_RS18805 (CSC33_3813) pilR 3929217..3930554 (+) 1338 WP_003094694.1 two-component system response regulator PilR Regulator
  CSC33_RS18810 (CSC33_3814) thiO 3930600..3931694 (-) 1095 WP_110194839.1 glycine oxidase ThiO -
  CSC33_RS18815 - 3931829..3932338 (+) 510 WP_110194330.1 Tfp pilus assembly protein FimT/FimU -
  CSC33_RS18820 (CSC33_3815) - 3932444..3932950 (+) 507 WP_003134935.1 Tfp pilus assembly protein FimT/FimU -
  CSC33_RS18825 (CSC33_3816) pilV 3932941..3933498 (+) 558 WP_003125211.1 type 4a pilus minor pilin PilV Machinery gene
  CSC33_RS18830 (CSC33_3817) pilW 3933495..3934319 (+) 825 WP_073649714.1 type 4a pilus minor pilin PilW -
  CSC33_RS18835 (CSC33_3818) pilX 3934316..3934903 (+) 588 WP_033972921.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49737.06 Da        Isoelectric Point: 5.8654

>NTDB_id=294762 CSC33_RS18805 WP_003094694.1 3929217..3930554(+) (pilR) [Pseudomonas aeruginosa strain AR_0446]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=294762 CSC33_RS18805 WP_003094694.1 3929217..3930554(+) (pilR) [Pseudomonas aeruginosa strain AR_0446]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAGCTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAGGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCTCTGCGCCTGCGCAACCCGGAGGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAATCACCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCATGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGTGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGAGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCAGCCGAAGTCGGCGCCGGGCGCTTCCGCCAAGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGACTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTTCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCGGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACGCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-115)

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZG94

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

100

100

1
  pilR Acinetobacter baumannii strain A118

51.198

100

0.528
  luxO Vibrio cholerae strain A1552

38.17

100

0.384

Multiple sequence alignment