Detailed information NTG0294698

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CSC53_RS15035
• Genome accession: NZ_CP029657
• Coordinates: 2809012..2809899 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain AR_0468
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2804012..2814899

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC53_RS15000	-	2804031..2804123 (+)	93	WP_010956583.1	hypothetical protein	-
CSC53_RS15005 (CSC53_2733)	-	2804231..2804728 (-)	498	WP_001065268.1	glutathione peroxidase	-
CSC53_RS15010	-	2804738..2804998 (-)	261	WP_001791974.1	hypothetical protein	-
CSC53_RS15020	-	2805380..2805493 (-)	114	Protein_2769	hypothetical protein	-
CSC53_RS15025 (CSC53_2734)	-	2806152..2808152 (-)	2001	WP_000776750.1	ABC transporter permease	-
CSC53_RS15030 (CSC53_2735)	-	2808149..2808904 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CSC53_RS15035 (CSC53_2736)	braS	2809012..2809899 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CSC53_RS15040 (CSC53_2737)	braR	2809910..2810575 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CSC53_RS15045 (CSC53_2738)	-	2810601..2810801 (-)	201	WP_000604730.1	hypothetical protein	-
CSC53_RS15050 (CSC53_2739)	-	2810999..2812423 (+)	1425	WP_000953755.1	alkaline phosphatase	-
CSC53_RS15530	-	2812493..2812603 (+)	111	Protein_2776	hypothetical protein	-
CSC53_RS15060 (CSC53_2740)	-	2812706..2813161 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CSC53_RS15065 (CSC53_2741)	-	2813406..2814167 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=294698 CSC53_RS15035 WP_000143425.1 2809012..2809899(-) (braS) [Staphylococcus aureus strain AR_0468]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=294698 CSC53_RS15035 WP_000143425.1 2809012..2809899(-) (braS) [Staphylococcus aureus strain AR_0468]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1