Detailed information NTG0029414

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: HAPS_RS09910
• Genome accession: NC_011852
• Coordinates: 2005440..2006114 (-)
• Length: 224 a.a.
• NCBI ID: WP_010787261.1
• Uniprot ID: B8F851
• Organism: Glaesserella parasuis SH0165
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2000440..2011114

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HAPS_RS09880 (HAPS_2037)	lolB	2000758..2001390 (+)	633	WP_015940037.1	lipoprotein insertase outer membrane protein LolB	-
HAPS_RS09885 (HAPS_2038)	ispE	2001392..2002237 (+)	846	WP_015940038.1	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	-
HAPS_RS09890 (HAPS_2039)	-	2002265..2003215 (+)	951	WP_005713153.1	ribose-phosphate pyrophosphokinase	-
HAPS_RS09895 (HAPS_2040)	pyrD	2003458..2004465 (+)	1008	WP_015940039.1	quinone-dependent dihydroorotate dehydrogenase	-
HAPS_RS09900	-	2004746..2004997 (-)	252	WP_041603192.1	hypothetical protein	-
HAPS_RS09905 (HAPS_2042)	-	2004994..2005185 (-)	192	WP_015940041.1	hypothetical protein	-
HAPS_RS09910 (HAPS_2043)	crp	2005440..2006114 (-)	675	WP_010787261.1	cAMP-activated global transcriptional regulator CRP	Regulator
HAPS_RS09915 (HAPS_2044)	-	2006181..2006405 (-)	225	WP_005713165.1	YheU family protein	-
HAPS_RS09920 (HAPS_2045)	slmA	2006413..2007018 (-)	606	WP_005713169.1	nucleoid occlusion factor SlmA	-
HAPS_RS09925 (HAPS_2046)	dut	2007027..2007482 (-)	456	WP_015940042.1	dUTP diphosphatase	-
HAPS_RS09930 (HAPS_2047)	-	2007508..2007834 (-)	327	WP_005713172.1	hypothetical protein	-
HAPS_RS09935 (HAPS_2048)	coaBC	2007844..2009046 (-)	1203	WP_010787262.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
HAPS_RS09940 (HAPS_2049)	radC	2009216..2009932 (+)	717	WP_010787263.1	RadC family protein	Machinery gene
HAPS_RS09945 (HAPS_2050)	rpmB	2010058..2010294 (+)	237	WP_005713177.1	50S ribosomal protein L28	-
HAPS_RS09950 (HAPS_2051)	rpmG	2010306..2010476 (+)	171	WP_005624479.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25208.17 Da
• Isoelectric Point: 6.9079

>NTDB_id=29414 HAPS_RS09910 WP_010787261.1 2005440..2006114(-) (crp) [Glaesserella parasuis SH0165]
MQDVSISTAQLEDVSPLPSIHDPSVEWFLTHCHIHRYPAKYTLIHAGEDAESLFYIVSGAVSVFIKDEEGKEMLLTNLGQ
GEFVGEISLFEEKAQPRTAWVRTKGNCEIAEISYKKFKQLVHLNPDILMYLSAQMARRLRMTSRQVSNLAFLDVTGRIAQ
TLMNLAKMPDAMTHPQGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide

• Length: 675 bp

>NTDB_id=29414 HAPS_RS09910 WP_010787261.1 2005440..2006114(-) (crp) [Glaesserella parasuis SH0165]
ATGCAAGATGTTTCAATCTCAACCGCACAGCTTGAAGATGTCAGCCCATTACCATCCATTCACGATCCTTCGGTGGAATG
GTTTTTAACTCACTGTCATATTCATCGTTATCCAGCAAAATATACTTTAATTCACGCAGGTGAAGATGCTGAATCACTGT
TTTATATTGTCAGCGGAGCTGTGTCTGTCTTTATCAAGGATGAAGAAGGCAAGGAGATGTTATTAACCAATTTAGGACAA
GGCGAATTTGTCGGTGAAATCAGCCTTTTTGAAGAAAAGGCTCAGCCTCGCACTGCTTGGGTAAGAACTAAAGGCAACTG
TGAAATTGCTGAAATTTCTTATAAAAAATTCAAGCAATTAGTGCATCTTAATCCAGATATTTTGATGTATTTATCCGCAC
AGATGGCTCGCCGTTTACGAATGACATCAAGGCAGGTTAGCAACCTAGCATTTCTTGATGTAACAGGTCGTATTGCTCAA
ACATTGATGAATTTAGCTAAAATGCCTGATGCGATGACTCACCCTCAGGGTATGCAGATTAAAATTACTCGCCAAGAAAT
TGGTCAAATGGTTGGTTGCTCACGAGAAACTGTAGGCCGTATTTTGAAAATGCTTGAGGATGAAGGGTTAATCTCTGCAC
ATGGTAAAACTATCGTTGTGTATGGGACAAGATAA

Domains

Predicted by InterProScan.

• Cyclic nucleotide-binding domain (cNMP_binding) (35-121)

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

3D structure

• AlphaFold DB: B8F851

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	75.862	90.625	0.687
crp	Haemophilus influenzae Rd KW20	73.399	90.625	0.665
crp	Acinetobacter baumannii D1279779	48.5	89.286	0.433