Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DK182_RS07835 Genome accession   NZ_CP029491
Coordinates   1618933..1620294 (-) Length   453 a.a.
NCBI ID   WP_019769001.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain 10919     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1613933..1625294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK182_RS07820 (DK181_07820) trkA 1615022..1616371 (+) 1350 WP_109833646.1 Trk system potassium transporter TrkA -
  DK182_RS07825 (DK181_07825) - 1616382..1617821 (+) 1440 WP_019769003.1 TrkH family potassium uptake protein -
  DK182_RS07830 (DK181_07830) vicX 1618131..1618940 (-) 810 WP_019777039.1 MBL fold metallo-hydrolase Regulator
  DK182_RS07835 (DK181_07835) vicK 1618933..1620294 (-) 1362 WP_019769001.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DK182_RS07840 (DK181_07840) vicR 1620287..1620994 (-) 708 WP_002960995.1 response regulator YycF Regulator
  DK182_RS07845 (DK181_07845) - 1621220..1621984 (+) 765 WP_002960993.1 amino acid ABC transporter ATP-binding protein -
  DK182_RS07850 (DK181_07850) - 1621998..1622822 (+) 825 WP_002960992.1 transporter substrate-binding domain-containing protein -
  DK182_RS07855 (DK181_07855) - 1622838..1623545 (+) 708 WP_002960990.1 amino acid ABC transporter permease -
  DK182_RS07860 (DK181_07860) - 1623560..1624210 (+) 651 WP_019768824.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 51831.33 Da        Isoelectric Point: 4.3763

>NTDB_id=293224 DK182_RS07835 WP_019769001.1 1618933..1620294(-) (vicK) [Streptococcus sobrinus strain 10919]
MNNNPVVENLNTFELALLILLALVALYFIYQAVREYRNAKTIRAISQKVTSLIAGDYTEDLHLKGDSELIELGTNLNDLS
DVLHLTHENLSQERNRLASVLSYMSDGVLATNRVGKITMINDTARKQLNLTREEALEMNIMDLIDSDDYDYRDLITQTPE
VTLYRRNEYDEFITLRVNFALNRRESGFISGLVAVLHDTTEQEKEERERRLFVSTVSHELRTPLTSVKSYLEALNEGALN
EDVAPSFIQVSLDETNRMMRMISDLLQLSRIDNDTSHLEVEMTNFTAFITVILNRFDQIKSQQDSDKDYEIVRNYPLNPI
WVEIDTDKMTQVLDNILNNAIKYSPDGGEITVSMTTTDTQLIISISDQGLGIPKKDLPMIFDRFYRVDKARSRAQGGTGL
GLAIAKEIIKQHHGFIWAKSEYGKGSTFTIVLPYDKEPDDFDDEWEEEESVND

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=293224 DK182_RS07835 WP_019769001.1 1618933..1620294(-) (vicK) [Streptococcus sobrinus strain 10919]
ATGAATAATAATCCTGTTGTTGAAAATCTCAATACCTTTGAATTAGCCCTGCTCATTCTTTTGGCCCTAGTTGCCCTTTA
TTTTATTTATCAAGCAGTGCGGGAGTACCGCAATGCTAAGACCATTCGTGCTATTAGCCAAAAGGTAACCAGCCTGATTG
CTGGTGATTACACGGAGGATCTTCACTTAAAAGGGGATTCTGAATTGATTGAGCTGGGGACCAACTTGAATGACCTGTCA
GATGTTTTGCATTTGACCCATGAAAATCTTTCACAAGAGCGCAATCGCCTAGCTTCCGTCCTGTCCTATATGAGTGATGG
GGTTTTAGCGACCAATCGGGTTGGAAAAATTACCATGATCAATGATACGGCCCGCAAGCAGCTCAATCTAACCCGAGAAG
AAGCGCTTGAGATGAACATCATGGATTTGATTGACTCGGATGACTATGATTATCGCGATTTGATAACCCAGACTCCAGAG
GTGACTCTCTACCGTCGCAACGAGTACGATGAGTTTATCACCTTGCGGGTTAATTTTGCCCTCAACCGTCGGGAGAGTGG
CTTTATTTCTGGTCTGGTTGCTGTCTTGCACGATACCACTGAGCAGGAGAAGGAAGAGCGAGAGCGTCGTCTCTTTGTCT
CTACCGTCAGCCATGAATTGCGGACCCCCTTGACCTCAGTCAAGTCCTACTTGGAGGCCCTCAATGAAGGGGCCCTCAAT
GAGGATGTGGCCCCCAGCTTTATTCAAGTCTCGTTAGATGAAACCAACCGCATGATGCGGATGATTTCTGATCTCTTACA
ATTGTCGCGAATTGATAATGATACCAGCCACTTAGAAGTTGAAATGACCAACTTCACGGCCTTTATCACGGTTATTCTCA
ATCGTTTCGACCAGATTAAGAGCCAGCAGGACTCCGACAAGGACTATGAAATCGTCCGTAATTATCCCCTCAATCCAATC
TGGGTTGAAATTGATACCGATAAGATGACCCAGGTTTTGGATAATATTCTCAATAATGCCATCAAGTATTCACCTGATGG
TGGCGAGATTACTGTCTCAATGACGACGACCGATACCCAGTTGATTATTTCAATCTCTGACCAAGGTCTGGGTATCCCTA
AGAAGGACCTGCCGATGATTTTCGACCGTTTCTATCGGGTTGATAAGGCCCGCAGTCGGGCTCAAGGCGGTACTGGTTTA
GGCTTGGCCATTGCTAAGGAAATTATAAAGCAGCATCATGGTTTTATTTGGGCTAAGAGTGAATATGGTAAGGGCTCAAC
CTTCACCATTGTCCTCCCTTACGACAAGGAGCCTGACGACTTTGATGATGAATGGGAGGAAGAAGAGTCAGTCAATGACT
AA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(97-161)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.396

91.391

0.68
  micB Streptococcus pneumoniae Cp1015

69.267

93.377

0.647

Multiple sequence alignment