Detailed information NTG0292248

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: DF184_RS00325
• Genome accession: NZ_CP029398
• Coordinates: 53567..54466 (+)
• Length: 299 a.a.
• NCBI ID: WP_012774888.1
• Uniprot ID: A0A116VRL0
• Organism: Streptococcus suis strain HN105
• Function: activate transcription of comX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	55102..56040	53567..54466	flank	636

Gene organization within MGE regions

Location: 53567..56040

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DF184_RS00325 (DF184_00325)	comR	53567..54466 (+)	900	WP_012774888.1	helix-turn-helix domain-containing protein	Regulator
DF184_RS00335 (DF184_00335)	-	55102..56040 (-)	939	WP_024402114.1	IS4 family transposase	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35405.30 Da
• Isoelectric Point: 4.6492

>NTDB_id=292248 DF184_RS00325 WP_012774888.1 53567..54466(+) (comR) [Streptococcus suis strain HN105]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide

• Length: 900 bp

>NTDB_id=292248 DF184_RS00325 WP_012774888.1 53567..54466(+) (comR) [Streptococcus suis strain HN105]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAATTCAAATGATTTATTTGTTTTACGAGACACGCTATTATCTTGCG
TAAATATATTAGGAAGCAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAGAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

• Helix-turn-helix domain (HTH_31) (5-60)

• ComR tetratricopeptide (ComR_TPR) (73-294)

3D structure

• AlphaFold DB: A0A116VRL0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis P1/7	100	100	1
comR	Streptococcus suis 05ZYH33	100	100	1
comR	Streptococcus suis D9	62.126	100	0.625
comR	Streptococcus mutans UA159	43.813	100	0.438
comR	Streptococcus pyogenes MGAS315	37.374	99.331	0.371