Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   AYP36_RS12670 Genome accession   NZ_CP034808
Coordinates   2643751..2644875 (+) Length   374 a.a.
NCBI ID   WP_000228545.1    Uniprot ID   -
Organism   Escherichia coli strain 08-3914     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2638751..2649875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AYP36_RS12645 mscL 2638877..2639287 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  AYP36_RS12650 trkA 2639417..2640793 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  AYP36_RS12655 rsmB 2640815..2642104 (-) 1290 WP_001301795.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  AYP36_RS12660 fmt 2642150..2643097 (-) 948 WP_000004459.1 methionyl-tRNA formyltransferase -
  AYP36_RS12665 def 2643112..2643621 (-) 510 WP_000114984.1 peptide deformylase -
  AYP36_RS12670 dprA 2643751..2644875 (+) 1125 WP_000228545.1 DNA-protecting protein DprA Machinery gene
  AYP36_RS12675 smg 2644847..2645320 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  AYP36_RS12680 yrdD 2645349..2645891 (+) 543 WP_001129722.1 type I DNA topoisomerase -
  AYP36_RS12685 tsaC 2645896..2646468 (+) 573 WP_001301437.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  AYP36_RS12690 aroE 2646473..2647291 (+) 819 WP_000451254.1 shikimate dehydrogenase -
  AYP36_RS12695 yrdB 2647288..2647545 (+) 258 WP_001070590.1 DUF1488 domain-containing protein -
  AYP36_RS12700 yrdA 2647521..2648075 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41034.02 Da        Isoelectric Point: 6.3845

>NTDB_id=291402 AYP36_RS12670 WP_000228545.1 2643751..2644875(+) (dprA) [Escherichia coli strain 08-3914]
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGRPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=291402 AYP36_RS12670 WP_000228545.1 2643751..2644875(+) (dprA) [Escherichia coli strain 08-3914]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCGACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Glaesserella parasuis strain SC1401

45.401

90.107

0.409
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.355

82.888

0.409
  dprA Vibrio cholerae strain A1552

49.355

82.888

0.409
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393

Multiple sequence alignment