Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DEH83_RS08855 Genome accession   NZ_CP029207
Coordinates   1749315..1750712 (+) Length   465 a.a.
NCBI ID   WP_255776640.1    Uniprot ID   -
Organism   Streptococcus constellatus strain TCV107     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1744315..1755712
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DEH83_RS08825 (DEH83_08855) - 1745425..1745682 (+) 258 WP_255776635.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
  DEH83_RS08830 (DEH83_08860) - 1745679..1746050 (+) 372 WP_255776636.1 type II toxin-antitoxin system death-on-curing family toxin -
  DEH83_RS08835 (DEH83_08865) - 1746142..1746393 (-) 252 WP_255776637.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
  DEH83_RS08840 (DEH83_08870) - 1746856..1747614 (+) 759 WP_255776638.1 alpha/beta hydrolase -
  DEH83_RS08845 (DEH83_08875) - 1747942..1748385 (+) 444 WP_255776639.1 hypothetical protein -
  DEH83_RS08850 (DEH83_08880) ciaR 1748651..1749325 (+) 675 WP_003068917.1 response regulator transcription factor Regulator
  DEH83_RS08855 (DEH83_08885) ciaH 1749315..1750712 (+) 1398 WP_255776640.1 cell wall metabolism sensor histidine kinase WalK Regulator
  DEH83_RS08860 (DEH83_08890) - 1751132..1752580 (-) 1449 WP_049493216.1 alpha-amylase -
  DEH83_RS08865 (DEH83_08895) - 1752758..1754371 (+) 1614 WP_255776642.1 M20/M25/M40 family metallo-hydrolase -
  DEH83_RS08870 (DEH83_08900) - 1754419..1754928 (-) 510 WP_049477276.1 DNA topology modulation protein -
  DEH83_RS08875 (DEH83_08905) rpsT 1754993..1755229 (-) 237 WP_006269392.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 465 a.a.        Molecular weight: 52879.82 Da        Isoelectric Point: 9.7225

>NTDB_id=291216 DEH83_RS08855 WP_255776640.1 1749315..1750712(+) (ciaH) [Streptococcus constellatus strain TCV107]
MLNKLKKAWYADDFSYFIRNFGIFTLIFSAMTLIIIQVMRSSLYTTVDNNLKSLSQDSASVINLALARKVGLEQKSENGE
PKSGTADKELTDKPNVSANTEVILFDKNYKPIITSNNFLGFNKLSFNSKQLDHIRQIQVKSNYGREETYRMILFEVKLPN
LETNVKYAAVFINISQLEQTSQNHEQLIVVVMISFWGISLIASVYLARVSVKPLLESIQKQKSFVENASHELRTPLAVLQ
NRLETLFRKPEATIMEASESIASSLDEVRNMKMLTTNLLNLARRDDGIKPEIGDVEPNFFNTTFTNYEMVAAENGKIFRF
DNRIHRVIKTDKTLLKQLMTILFDNALKYTDEDGVIELTISANDRNLFLKVSDNGPGISTADKKKIFDRFYRVDKARTRQ
TGGFGLGLSLAKQITEALKGTIAVKDNKPKGTIFEVKIAIRTDNKKEKIDLGYFQCTCKESYSER

Nucleotide


Download         Length: 1398 bp        

>NTDB_id=291216 DEH83_RS08855 WP_255776640.1 1749315..1750712(+) (ciaH) [Streptococcus constellatus strain TCV107]
ATGCTGAATAAACTAAAAAAAGCATGGTATGCGGATGATTTTTCTTATTTCATTCGCAATTTTGGTATTTTTACTCTCAT
TTTCTCAGCTATGACCTTGATTATCATTCAAGTTATGCGCTCAAGCCTTTATACAACGGTAGATAACAATTTAAAAAGCT
TGAGTCAAGATTCGGCTTCTGTGATTAATTTAGCACTTGCTCGAAAAGTAGGGCTAGAGCAAAAGTCAGAAAATGGAGAG
CCTAAAAGTGGAACAGCTGACAAAGAATTGACAGATAAACCAAATGTTAGTGCCAATACAGAAGTTATTTTATTTGATAA
GAATTATAAGCCGATTATTACAAGCAATAATTTCTTAGGGTTCAATAAGCTTTCCTTTAATAGCAAGCAATTAGACCACA
TTCGTCAGATTCAAGTAAAAAGCAATTATGGTCGAGAAGAAACCTATCGAATGATTTTATTTGAGGTAAAACTGCCTAAT
TTGGAGACCAATGTCAAATACGCAGCGGTTTTTATCAATATCAGTCAATTGGAACAAACTAGTCAAAATCATGAACAGTT
GATTGTGGTGGTGATGATTAGTTTCTGGGGAATTTCCTTGATTGCTAGTGTTTATCTTGCACGGGTCAGTGTTAAACCTC
TTTTAGAAAGCATTCAAAAGCAAAAAAGTTTTGTCGAAAACGCTAGTCATGAGTTGCGTACACCTCTAGCTGTGTTGCAA
AATCGTTTGGAGACTTTATTTAGAAAGCCAGAAGCTACTATTATGGAAGCCAGTGAAAGCATTGCTTCTAGTTTGGATGA
AGTGCGGAATATGAAAATGTTGACGACAAATTTACTCAATCTAGCACGGCGTGACGACGGGATTAAACCAGAAATTGGCG
ATGTCGAGCCAAATTTCTTTAATACAACTTTCACCAACTATGAAATGGTTGCCGCAGAGAATGGGAAAATTTTCCGATTT
GACAATAGGATTCACCGCGTAATTAAAACGGATAAAACCTTACTGAAGCAATTGATGACTATCTTGTTTGATAATGCCCT
GAAATATACAGATGAAGATGGTGTGATTGAATTGACAATCTCTGCAAATGATCGAAATTTGTTTTTGAAGGTTTCGGATA
ATGGTCCGGGGATTAGTACGGCAGATAAGAAAAAGATTTTTGATCGTTTTTATCGTGTTGATAAAGCACGGACTCGGCAG
ACAGGTGGTTTTGGTTTAGGGTTGTCGCTTGCAAAGCAAATCACAGAAGCTCTTAAAGGAACCATTGCAGTGAAAGACAA
TAAGCCTAAAGGAACTATTTTTGAGGTGAAGATTGCGATTCGAACGGATAATAAAAAAGAAAAAATAGATTTAGGATACT
TTCAGTGTACCTGTAAAGAAAGTTATTCCGAAAGATGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(222-287)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(331-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

70.759

96.344

0.682
  ciaH Streptococcus pneumoniae D39

70.759

96.344

0.682
  ciaH Streptococcus pneumoniae R6

70.759

96.344

0.682
  ciaH Streptococcus pneumoniae TIGR4

70.759

96.344

0.682
  ciaH Streptococcus mutans UA159

55.023

94.194

0.518

Multiple sequence alignment