Detailed information NTG0289386

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: DC427_RS14250
• Genome accession: NZ_CP029030
• Coordinates: 2726941..2727606 (-)
• Length: 221 a.a.
• NCBI ID: WP_000697886.1
• Uniprot ID: A0A0D3QBD0
• Organism: Staphylococcus aureus strain CAR
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2721941..2732606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DC427_RS14230	-	2722411..2722524 (-)	114	WP_001791776.1	hypothetical protein	-
DC427_RS14235	-	2723183..2725183 (-)	2001	WP_000776751.1	ABC transporter permease	-
DC427_RS14240	-	2725180..2725935 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
DC427_RS14245	braS	2726043..2726930 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
DC427_RS14250	braR	2726941..2727606 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
DC427_RS14255	-	2727632..2727832 (-)	201	WP_000604728.1	hypothetical protein	-
DC427_RS14260	-	2728030..2729454 (+)	1425	WP_000953744.1	alkaline phosphatase	-
DC427_RS14985	-	2729514..2729615 (-)	102	WP_000731972.1	SE2200 family small protein	-
DC427_RS14270	-	2729737..2730192 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
DC427_RS14275	-	2730437..2731198 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 221 a.a.
• Molecular weight: 25392.45 Da
• Isoelectric Point: 4.6846

>NTDB_id=289386 DC427_RS14250 WP_000697886.1 2726941..2727606(-) (braR) [Staphylococcus aureus strain CAR]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQNQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide

• Length: 666 bp

>NTDB_id=289386 DC427_RS14250 WP_000697886.1 2726941..2727606(-) (braR) [Staphylococcus aureus strain CAR]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAGAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAAAATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAGCCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-220)

• Response regulator receiver domain (Response_reg) (3-111)

3D structure

• AlphaFold DB: A0A0D3QBD0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	99.548	100	0.995