Detailed information NTG0028542

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: PSPA7_RS10415
• Genome accession: NC_009656
• Coordinates: 2232144..2234366 (+)
• Length: 740 a.a.
• NCBI ID: WP_012075162.1
• Uniprot ID: A6V3B4
• Organism: Pseudomonas paraeruginosa PA7
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2227144..2239366

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PSPA7_RS10390 (PSPA7_2172)	-	2227438..2228037 (-)	600	WP_003156867.1	PilZ domain-containing protein	-
PSPA7_RS10395 (PSPA7_2173)	-	2228140..2229390 (+)	1251	WP_003156868.1	lipoprotein-releasing ABC transporter permease subunit	-
PSPA7_RS10400 (PSPA7_2174)	lolD	2229383..2230066 (+)	684	WP_003091168.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
PSPA7_RS10405 (PSPA7_2175)	-	2230136..2231380 (+)	1245	WP_003156869.1	lipoprotein-releasing ABC transporter permease subunit	-
PSPA7_RS10410 (PSPA7_2176)	-	2231480..2232013 (-)	534	WP_012075161.1	DUF2062 domain-containing protein	-
PSPA7_RS10415 (PSPA7_2177)	comA	2232144..2234366 (+)	2223	WP_012075162.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
PSPA7_RS10420 (PSPA7_2178)	exbB	2234439..2235074 (+)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
PSPA7_RS10425 (PSPA7_2179)	-	2235071..2235511 (+)	441	WP_012075163.1	ExbD/TolR family protein	-
PSPA7_RS10430 (PSPA7_2180)	lpxK	2235511..2236509 (+)	999	WP_003157521.1	tetraacyldisaccharide 4'-kinase	-
PSPA7_RS10435 (PSPA7_2181)	-	2236547..2236732 (+)	186	WP_003157522.1	Trm112 family protein	-
PSPA7_RS10440 (PSPA7_2182)	kdsB	2236732..2237496 (+)	765	WP_012075164.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
PSPA7_RS10445 (PSPA7_2183)	-	2237496..2237960 (+)	465	WP_012075165.1	low molecular weight protein-tyrosine-phosphatase	-
PSPA7_RS10450 (PSPA7_2184)	murB	2237957..2238976 (+)	1020	WP_012075166.1	UDP-N-acetylmuramate dehydrogenase	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 79620.04 Da
• Isoelectric Point: 10.7311

>NTDB_id=28542 PSPA7_RS10415 WP_012075162.1 2232144..2234366(+) (comA) [Pseudomonas paraeruginosa PA7]
MRLGLPALAAGLLALRLLPELPSAGWLLAAAAAGLLLLFGRLYWLGLFLLGFAWACVSAQAALDGRLAAELDGRTLWLEG
RISGLPASGNGVTRFQLEGVSSPREALPGRLRLSWRGAPPLMGGERWRLAVNLKRPRGLVNTAGFDYEAWLLAQRIGAIG
TVKAGERLRPASGLDAWRDAWRQRLLAADTQGRGGALAALVLGDGSGLRADEWRMLQDTGTVHLMVISGSHISLLAGMLY
GLVAGLFRLGCWPRRLPWLPCACGLALAGAWGYGLMAGFEVPVRRACLMVSLALLWRLRFRHLGVSRPLLGTLVLVLLAE
PLACLQAGFWLSFLAVALLLWLFAGRLGRWRWWTAWGRAQWGMALGLAMPSLALGLPLSLSGALANLLAVPWVEMLVVPP
ALAGSLLLGVPGVGESLLWIAGASLDQLFHLLVLLAGLAGAWQPPAATAWGVALGMLGALCWLAPAGLPVRGLGALLMLP
ALAPLLRPIEAGYAEVRMLDVGQGLAVLLRTRGHALLYDAGARQGDFDMGERVVLPVLRSLDLRRLDGLLLSHADNDHAG
GAPAVVSRFAPGWVVSGEPARLPSSLAARGCEERRWEWDGVTFAQWSWARADSANDRSCVLRVEARGEVLLLTGDIARAA
EYAWLARQGEPRVDWLQAPHHGSRSSSGEAFVRRTRPHHVLVSRGWRNAFGHPHAEVVQRYAGIAAQIHDTARDGALTFT
LGRGGEARGEREAAHFWREK

Nucleotide

• Length: 2223 bp

>NTDB_id=28542 PSPA7_RS10415 WP_012075162.1 2232144..2234366(+) (comA) [Pseudomonas paraeruginosa PA7]
ATGCGCCTGGGATTGCCAGCCCTCGCCGCGGGGCTGCTGGCCCTGCGCCTGCTGCCGGAGTTGCCGTCGGCTGGCTGGCT
GCTGGCGGCCGCCGCTGCCGGTCTGCTGCTGCTCTTCGGCCGTCTCTACTGGCTGGGACTGTTCCTGCTCGGCTTCGCCT
GGGCCTGCGTGTCGGCACAGGCCGCGCTGGACGGGCGCCTCGCCGCCGAGCTGGATGGCCGTACGCTATGGCTGGAAGGG
CGTATCAGCGGCCTGCCGGCAAGCGGGAATGGCGTCACGCGCTTCCAGTTGGAGGGCGTGAGCAGCCCGCGCGAAGCGCT
GCCTGGCCGCCTGCGCCTGAGCTGGCGCGGCGCGCCGCCACTCATGGGAGGTGAGCGCTGGCGCCTGGCGGTGAACCTGA
AGCGGCCGCGCGGCCTGGTGAATACGGCAGGCTTCGATTACGAAGCCTGGCTGCTGGCGCAGCGGATCGGCGCCATCGGC
ACGGTGAAGGCGGGCGAGCGGTTGCGTCCGGCCAGCGGCCTGGATGCCTGGCGCGACGCCTGGCGCCAGCGTCTGCTCGC
GGCGGATACCCAGGGTCGCGGCGGCGCGCTGGCGGCGCTGGTGCTGGGAGACGGCTCGGGCTTGCGCGCGGATGAATGGC
GCATGCTCCAGGACACCGGCACCGTGCACCTGATGGTGATTTCCGGATCGCATATCTCGCTGTTGGCGGGAATGCTCTAT
GGCCTGGTGGCGGGCCTGTTCCGCCTGGGTTGCTGGCCTCGCCGCCTGCCCTGGCTGCCCTGCGCCTGCGGCCTGGCGCT
GGCTGGTGCCTGGGGCTACGGGCTGATGGCGGGATTCGAGGTGCCGGTGCGGCGCGCCTGCCTGATGGTCAGCCTGGCGC
TGCTCTGGCGCCTGCGCTTCCGTCACCTGGGCGTGTCGAGGCCGCTGCTCGGGACGCTGGTGCTGGTGCTCCTGGCGGAG
CCGCTGGCCTGCCTGCAGGCGGGATTCTGGCTGTCGTTCCTGGCGGTGGCGTTGCTGCTCTGGCTGTTCGCCGGGCGCCT
CGGGCGCTGGCGCTGGTGGACGGCCTGGGGGCGGGCGCAATGGGGCATGGCGCTCGGGCTGGCGATGCCGTCGCTGGCGC
TGGGCCTGCCGTTGAGCCTGAGCGGGGCGCTGGCGAACCTGCTGGCGGTGCCCTGGGTAGAAATGCTGGTAGTGCCGCCG
GCCCTGGCCGGGAGCCTGTTGCTCGGTGTGCCTGGCGTCGGCGAGAGCCTGTTGTGGATCGCTGGCGCCTCGCTGGACCA
ACTGTTCCACCTGCTCGTCCTGCTGGCGGGGCTGGCCGGGGCCTGGCAGCCGCCTGCCGCCACGGCCTGGGGCGTCGCCC
TGGGAATGCTCGGCGCGCTCTGCTGGCTGGCGCCAGCCGGGTTGCCGGTGCGAGGCCTGGGGGCGTTGCTGATGCTACCG
GCGCTGGCGCCGTTGCTGCGACCGATCGAGGCGGGGTATGCCGAGGTGCGGATGCTGGATGTCGGCCAGGGGCTGGCGGT
GCTGCTGCGTACCCGCGGGCACGCGCTGCTGTATGACGCCGGTGCGCGACAGGGCGACTTCGACATGGGCGAGCGGGTGG
TCCTGCCGGTGCTGCGCAGCCTCGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCACGCCGACAACGACCATGCCGGT
GGCGCGCCTGCGGTGGTTTCCCGTTTCGCCCCGGGCTGGGTGGTCAGTGGCGAGCCGGCGCGCCTGCCGTCGTCGCTGGC
GGCGCGGGGATGCGAGGAGCGGCGCTGGGAGTGGGACGGCGTGACCTTCGCCCAGTGGTCATGGGCCCGGGCCGACAGCG
CTAACGACCGTTCCTGCGTGTTGCGGGTGGAAGCGCGCGGCGAGGTGCTGCTGCTGACCGGCGACATCGCGCGCGCTGCC
GAGTACGCCTGGCTGGCGCGCCAGGGCGAGCCGCGGGTCGACTGGTTGCAGGCGCCACATCATGGCAGTCGCAGTTCCTC
CGGAGAGGCCTTCGTGCGACGGACCCGGCCGCACCATGTGCTGGTCTCGCGGGGTTGGCGCAATGCCTTCGGCCATCCTC
ATGCGGAAGTGGTGCAGCGCTACGCCGGCATCGCCGCGCAGATCCACGACACCGCTCGCGACGGAGCCCTGACCTTTACC
CTGGGGCGCGGCGGGGAGGCACGCGGGGAGCGTGAAGCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (500-675)

• Domain of unknown function (DUF4131) (DUF4131) (20-167)

• Competence protein (Competence) (200-463)

3D structure

• AlphaFold DB: A6V3B4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	59.306	97.297	0.577
comA	Ralstonia pseudosolanacearum GMI1000	35.248	100	0.365