Detailed information NTG0028512

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: APP7_RS10715
• Genome accession: NC_010939
• Coordinates: 2256061..2256735 (-)
• Length: 224 a.a.
• NCBI ID: WP_005599747.1
• Uniprot ID: -
• Organism: Actinobacillus pleuropneumoniae serovar 7 str. AP76
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2251061..2261735

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
APP7_RS10685 (APP7_2047)	adhP	2251158..2252207 (+)	1050	WP_005602862.1	alcohol dehydrogenase AdhP	-
APP7_RS10690 (APP7_2048)	miaA	2252339..2253282 (+)	944	Protein_2053	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	-
APP7_RS10695 (APP7_2049)	hfq	2253347..2253625 (+)	279	WP_005599741.1	RNA chaperone Hfq	-
APP7_RS10700 (APP7_2050)	hflX	2253807..2255030 (+)	1224	WP_005618410.1	ribosome rescue GTPase HflX	-
APP7_RS10705 (APP7_2051)	-	2255066..2255626 (-)	561	WP_005613491.1	TIGR00730 family Rossman fold protein	-
APP7_RS10710 (APP7_2052)	-	2255689..2256012 (+)	324	WP_005602867.1	MazG-like family protein	-
APP7_RS10715 (APP7_2053)	crp	2256061..2256735 (-)	675	WP_005599747.1	cAMP-activated global transcriptional regulator CRP	Regulator
APP7_RS10720 (APP7_2054)	-	2256813..2257031 (-)	219	WP_005599748.1	YheU family protein	-
APP7_RS10725 (APP7_2055)	slmA	2257037..2257645 (-)	609	WP_005620316.1	nucleoid occlusion factor SlmA	-
APP7_RS10730 (APP7_2056)	dut	2257751..2258206 (-)	456	WP_005599752.1	dUTP diphosphatase	-
APP7_RS10735 (APP7_2057)	coaBC	2258215..2259420 (-)	1206	WP_005602882.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
APP7_RS10740 (APP7_2058)	radC	2259628..2260290 (+)	663	WP_005599756.1	DNA repair protein RadC	Machinery gene
APP7_RS10745 (APP7_2059)	rpmB	2260459..2260695 (+)	237	WP_005599762.1	50S ribosomal protein L28	-
APP7_RS10750 (APP7_2060)	rpmG	2260707..2260877 (+)	171	WP_005599764.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25147.02 Da
• Isoelectric Point: 6.5834

>NTDB_id=28512 APP7_RS10715 WP_005599747.1 2256061..2256735(-) (crp) [Actinobacillus pleuropneumoniae serovar 7 str. AP76]
MQDISISTPQLDSELSAPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEDAESLFYIVSGSVAVFIKDEEGKEMILSHLGQ
GEFVGEISLFEDTIQPRTAWVKTKGACEIAEISYKKFKQLVHLNPDILMYLSAQMARRLRQTSRQVSNLAFLDVTGRIAQ
TLMNLAKMPDAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide

• Length: 675 bp

>NTDB_id=28512 APP7_RS10715 WP_005599747.1 2256061..2256735(-) (crp) [Actinobacillus pleuropneumoniae serovar 7 str. AP76]
ATGCAAGATATTTCAATTTCAACACCTCAGCTAGACAGTGAGCTGTCCGCCCCGTCTATTCATGATCCGGCGGTGGAATG
GTTTCTGACTCACTGTCATATTCATCGTTATCCGTCAAAATATACGCTTATTCATGCGGGTGAGGATGCCGAATCATTAT
TCTATATCGTCAGCGGCTCCGTTGCAGTGTTTATTAAAGATGAAGAAGGGAAAGAAATGATCCTTTCTCACCTCGGTCAA
GGTGAATTTGTCGGTGAAATCAGTTTATTCGAAGACACTATTCAACCGCGTACCGCTTGGGTCAAAACCAAAGGCGCTTG
CGAAATTGCGGAAATCTCGTATAAAAAATTCAAACAGCTTGTGCATTTAAATCCGGATATTCTTATGTATCTTTCCGCGC
AAATGGCTCGCCGCCTACGCCAAACCTCACGCCAAGTAAGTAACCTCGCTTTCTTAGACGTAACCGGTCGTATCGCACAA
ACCTTAATGAATTTGGCGAAAATGCCGGATGCGATGACCCATCCGGAAGGAATGCAAATTAAGATTACCCGCCAAGAAAT
CGGTCAAATGGTCGGTTGTTCTCGAGAAACGGTCGGTAGAATCTTAAAAATGCTAGAAGATGAAGGCTTAATTTCAGCAC
ACGGTAAAACCATTGTCGTTTATGGCACTCGCTAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

• Cyclic nucleotide-binding domain (cNMP_binding) (36-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	77.34	90.625	0.701
crp	Haemophilus influenzae Rd KW20	73.892	90.625	0.67
crp	Acinetobacter baumannii D1279779	45.794	95.536	0.437