Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   EGX82_RS06430 Genome accession   NZ_CP033822
Coordinates   1205000..1206979 (+) Length   659 a.a.
NCBI ID   WP_001054074.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain FDAARGOS_512     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1200000..1211979
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX82_RS06410 (EGX82_06410) argR 1201450..1201887 (+) 438 WP_001033152.1 arginine repressor -
  EGX82_RS06415 (EGX82_06415) hexA 1201944..1204520 (+) 2577 WP_001118377.1 DNA mismatch repair protein MutS Machinery gene
  EGX82_RS06420 (EGX82_06420) - 1204577..1204780 (-) 204 WP_000191849.1 cold shock domain-containing protein -
  EGX82_RS06430 (EGX82_06430) hexB 1205000..1206979 (+) 1980 WP_001054074.1 DNA mismatch repair endonuclease MutL Machinery gene
  EGX82_RS06435 (EGX82_06435) - 1207011..1208243 (+) 1233 WP_000657476.1 MFS transporter -
  EGX82_RS06440 (EGX82_06440) ruvA 1208245..1208835 (+) 591 WP_000272487.1 Holliday junction branch migration protein RuvA Machinery gene
  EGX82_RS06445 (EGX82_06445) - 1208858..1209409 (+) 552 WP_000817341.1 DNA-3-methyladenine glycosylase I -
  EGX82_RS06450 (EGX82_06450) cinA 1209498..1210757 (+) 1260 WP_001200978.1 competence/damage-inducible protein A Machinery gene
  EGX82_RS06455 (EGX82_06455) recA 1210831..1211970 (+) 1140 WP_001085741.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 659 a.a.        Molecular weight: 73986.20 Da        Isoelectric Point: 5.4718

>NTDB_id=284928 EGX82_RS06430 WP_001054074.1 1205000..1206979(+) (hexB) [Streptococcus agalactiae strain FDAARGOS_512]
MNLSKIIELPDILANQIAAGEVVERPSSVVKELVENAIDAGSSQITIEVEESGLKKIQITDNGEGMTSEDAVLSLRRHAT
SKIKSQSDLFRIRTLGFRGEALPSIASISLMTIKTATEQGKQGTLLVAKGGNIEKQEVVSSPRGTKILVENLFFNTPARL
KYMKSLQSELAHIIDIVNRLSLAHPEVAFTLINDGKEMTKTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEISGYVS
LPELTRANRNYITLLINGRYIKNFLLNRSILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKERELMSLI
STAISESLKQYDLIPDALENLAKTSTRSVDKPIQTSFSLKQPGLYYDRAKNDFFIGADTVSEPIANFTNLDKSDGSVDND
VKNSVNQGATQSPNIKYASRDQADSENFIHSQDYLSSKQSLNKLVEKLDSEESSTFPELEFFGQMHGTYLFAQGNGGLYI
IDQHAAQERVKYEYYREKIGEVDNSLQQLLVPFLFEFSSSDFLQLQEKMSLLQDVGIFLEPYGNNTFILREHPIWMKEEE
VESGIYEMCDMLLLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARHLLDQLAQCKNPYNCPHGRPVLVNFTKADME
KMFKRIQENHTSLRDLGKY

Nucleotide


Download         Length: 1980 bp        

>NTDB_id=284928 EGX82_RS06430 WP_001054074.1 1205000..1206979(+) (hexB) [Streptococcus agalactiae strain FDAARGOS_512]
ATGAACTTGTCTAAAATTATTGAATTACCGGATATATTAGCTAACCAGATTGCTGCTGGTGAGGTTGTTGAAAGGCCTAG
TAGCGTCGTTAAAGAATTAGTTGAAAATGCCATAGATGCAGGAAGTAGCCAAATTACCATAGAGGTTGAAGAATCTGGTC
TTAAAAAGATTCAAATAACGGATAACGGTGAAGGGATGACTAGTGAGGATGCCGTTCTCAGTTTACGACGTCACGCTACA
TCCAAAATCAAAAGCCAGAGTGACCTTTTTCGTATTCGGACCTTAGGTTTTCGTGGTGAAGCTCTACCATCAATCGCTTC
GATTAGTTTAATGACGATAAAAACAGCTACAGAGCAAGGGAAACAAGGGACGTTACTTGTTGCTAAAGGGGGAAACATTG
AAAAACAGGAAGTTGTTTCAAGTCCTCGTGGAACAAAAATTTTAGTTGAAAATTTATTCTTTAACACGCCTGCCAGATTG
AAATACATGAAGAGTTTACAGTCTGAACTAGCTCATATTATTGATATTGTTAATAGACTCAGTCTAGCGCATCCGGAAGT
TGCTTTTACACTGATAAATGATGGTAAAGAAATGACTAAAACTAGTGGGACTGGCGATTTGAGACAGGCGATTGCAGGTA
TTTATGGTTTAAATACTGCAAAAAAAATGATTGAGATTTCAAATGCAGATTTAGATTTTGAAATTTCGGGTTATGTAAGT
TTGCCTGAATTGACACGAGCTAACCGAAACTATATTACCCTATTAATTAACGGTCGTTACATTAAAAATTTTCTTTTGAA
CCGCTCAATTCTAGATGGTTATGGTTCAAAGTTGATGGTTGGAAGATTTCCAATTGCTGTCATTGATATTCAGATAGATC
CTTATCTAGCAGATGTCAACGTTCATCCGACTAAGCAAGAGGTGAGAATTTCTAAGGAACGAGAATTAATGAGTTTAATA
AGCACAGCAATTTCTGAGAGTCTTAAACAATATGACTTGATTCCGGATGCTTTAGAGAATTTAGCTAAAACTAGTACCCG
AAGTGTAGATAAGCCTATACAAACAAGCTTCTCACTAAAACAGCCTGGTTTGTATTACGATAGGGCTAAAAATGACTTTT
TTATAGGTGCAGATACTGTATCTGAACCTATTGCTAACTTTACAAACCTTGACAAAAGTGACGGTTCAGTTGACAATGAT
GTAAAAAACTCTGTTAATCAAGGAGCAACGCAGTCTCCTAATATAAAGTATGCTAGTAGAGATCAAGCTGATAGTGAGAA
CTTCATTCATTCTCAGGATTACCTTAGTAGTAAACAGTCACTTAACAAACTTGTTGAAAAATTAGATTCGGAAGAAAGTT
CGACTTTTCCAGAGCTCGAATTTTTTGGTCAAATGCATGGGACCTACTTATTTGCTCAAGGGAATGGTGGGTTGTATATT
ATTGATCAACATGCAGCTCAAGAGCGTGTAAAATACGAGTATTACCGTGAAAAGATAGGTGAGGTTGATAATAGTCTTCA
ACAATTGTTAGTACCATTTCTATTTGAATTTTCAAGTTCAGATTTTCTTCAATTACAAGAAAAAATGTCATTATTACAAG
ATGTTGGTATTTTCTTGGAACCGTATGGTAATAATACTTTCATTTTAAGGGAACATCCAATTTGGATGAAAGAAGAAGAG
GTAGAGTCTGGCATTTATGAAATGTGTGATATGTTGTTGCTCACTAATGAAGTATCAGTGAAAAAATATCGCGCAGAGTT
GGCTATTATGATGTCTTGCAAGCGATCTATTAAAGCAAACCATACGCTAGACGATTACTCAGCACGTCATTTATTAGATC
AGTTAGCGCAATGTAAAAATCCTTATAATTGCCCTCATGGAAGACCTGTTTTAGTTAATTTTACAAAAGCTGATATGGAG
AAAATGTTTAAACGAATCCAAGAAAATCATACAAGCCTCAGGGATTTAGGAAAATATTGA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(460-603)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(211-328)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(27-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.892

100

0.689

Multiple sequence alignment