Detailed information NTG0284765

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EGX80_RS00825
• Genome accession: NZ_CP033815
• Coordinates: 153725..155968 (-)
• Length: 747 a.a.
• NCBI ID: WP_011106716.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain FDAARGOS_514
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 148725..160968

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX80_RS00795 (EGX80_00795)	-	149364..150584 (+)	1221	WP_011054655.1	DUF3114 domain-containing protein	-
EGX80_RS00800 (EGX80_00800)	-	150698..151288 (-)	591	WP_002983984.1	serine hydrolase	-
EGX80_RS00805 (EGX80_00805)	-	151285..151533 (-)	249	WP_011054656.1	hypothetical protein	-
EGX80_RS00810 (EGX80_00810)	-	151518..151745 (-)	228	WP_011054657.1	hypothetical protein	-
EGX80_RS00815 (EGX80_00815)	sodA	151912..152517 (-)	606	WP_011054658.1	superoxide dismutase SodA	-
EGX80_RS00820 (EGX80_00820)	holA	152614..153654 (-)	1041	WP_011054659.1	DNA polymerase III subunit delta	-
EGX80_RS00825 (EGX80_00825)	comEC/celB	153725..155968 (-)	2244	WP_011106716.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EGX80_RS00830 (EGX80_00830)	comEA/celA/cilE	155949..156611 (-)	663	WP_002995626.1	ComEA family DNA-binding protein	Machinery gene
EGX80_RS00835 (EGX80_00835)	-	156811..157551 (-)	741	WP_011054661.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
EGX80_RS00840 (EGX80_00840)	-	157669..158445 (+)	777	WP_002994360.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
EGX80_RS00845 (EGX80_00845)	-	158435..158713 (+)	279	WP_002989164.1	GIY-YIG nuclease family protein	-
EGX80_RS00850 (EGX80_00850)	-	158737..160736 (-)	2000	Protein_168	potassium transporter Kup	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 85572.51 Da
• Isoelectric Point: 9.7095

>NTDB_id=284765 EGX80_RS00825 WP_011106716.1 153725..155968(-) (comEC/celB) [Streptococcus pyogenes strain FDAARGOS_514]
MTFSWTKLVPLSKIQFAFLILVLFYQIHSPSWLTFLLSLSLICLLVKRLSKKEFLGVFAILSFCALFLLYQKQQLVQKLE
IQPVQITSVALVPDSIRINGDQLAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQT
FLAYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRRMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELPFACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFL
WDAHFLMTVGGVLTFSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTALLSYLFDLFILPLL
CLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLILVISFAIFYDYRQVRQRVITCGLVIALTLLS
VKYPLINEVTFIDIGQGDSILVREWTGKNLLIDVGGRPFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVTHAD
TDHMGDIEVVAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPWQLGDGKNNDSLVLYGR
LLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDR
QITYYRTDTQGAIRLTGWTSWHLETVR

Nucleotide

• Length: 2244 bp

>NTDB_id=284765 EGX80_RS00825 WP_011106716.1 153725..155968(-) (comEC/celB) [Streptococcus pyogenes strain FDAARGOS_514]
ATGACATTTTCTTGGACTAAGCTAGTGCCCCTGTCAAAGATTCAATTTGCTTTTTTAATCTTGGTTCTCTTTTATCAAAT
CCATAGCCCTAGCTGGTTAACGTTTCTCCTTAGCCTTAGTTTGATTTGCTTACTTGTCAAGCGTTTGTCTAAAAAAGAAT
TTCTCGGTGTCTTTGCCATCCTTAGTTTCTGTGCTTTGTTTTTGCTGTATCAGAAACAGCAGTTGGTTCAAAAACTGGAA
ATTCAGCCAGTACAAATAACCTCTGTAGCATTAGTTCCTGATAGTATTCGGATTAATGGTGATCAATTAGCTGTTCTTGG
ACGTCATGGGAAACATTCTTATCAGTTATTTTACCGTTTGAAAAGCCAAGCAGAAGCCCAATTGTTCAAGAAAGAGCACC
GTTGGTTAGTGATGCACGCAAAAGTGACATTGGAAAAAGCTGAGGAAGTTCGAAATTTTAAAGGCTTTAATTATCAGACT
TTTTTGGCTTATCAAGGAATTTACAGGATAGGGAAGGTAGAGCAAATAGAACAGCTTGAAGTGATTTCACCCGAGTCAAT
ATGTGACTATTTGTCCTCTTTAAGACGGCGAGCCATTGTTCATTGCCAGCAGCATTTTCCAAGACGTATGTCTCACTACC
TGACGGGCCTCCTTTTTGGTTATTTAGATAAGTCGTTTGGTGAGATGACAGATTATTATAGTCAGTTGGGTATCATTCAT
CTCTTTGCTTTATCAGGGATGCAGGTTGGCTTCTTTCTCACTTGTTTTAGAAGGGTGTTGCTATTACTCGCAGTTCCTTT
GGAATGGATAAAATGGATAGAGCTTCCTTTTGCTTGCTTTTATGCCGCGTTGACAGGTTATAGTATTTCTGTTATTCGAA
GCCTCGTGCAGTCGCAGTTGCGTCATTTAGGAATAAAAGGATTAGACAATCTCGCTTGTACTTTTTTACTTGTCTTTTTA
TGGGATGCCCATTTCTTAATGACTGTTGGTGGCGTATTAACGTTTAGCTATGCTTTTTTGTTAACAGTGGTTACTGTTGA
AGAATTATCAGGAGCTAAAAGACAGTTGGTACAAGTCTTGACCATTTCCCTAGGAATATTACCATTTTTGCTCTTTTATT
TTTCCAGTTTTAACCCAATGTCAATGGTCTTAACAGCTCTCTTGTCTTATCTCTTTGACCTTTTTATTTTACCTCTTCTT
TGTCTGGTTTTTTGTCTATCCCCTTTGGTGACTGTCTCAATATGCAACCATCTTTTTATTTTATTAGAAAAAGTCATTCA
ATTTCTCGGAAATACTTTCAATAGTTCCCTTGTTTTTGGAAGCCCGACCAGTTGGCACTTGCTTATCTTGGTGATTAGCT
TCGCTATTTTTTATGATTATCGGCAGGTGCGACAACGAGTTATCACTTGCGGTTTGGTTATAGCGTTGACGCTTTTGTCT
GTCAAATATCCTTTGATCAATGAAGTGACCTTTATCGACATTGGCCAGGGAGATAGTATTTTGGTGAGGGAGTGGACAGG
GAAAAATCTCTTAATAGATGTAGGTGGGCGCCCTTTCTTTTCTTCAAAAGAGCACTGGCGACGAGGACATCACGTAGCTA
ATGCTCAGAAAACCTTAATTCCTTACTTAAAAAGTAGAGGTATTCACACAATTGACCAACTATTAGTAACTCACGCAGAT
ACTGATCATATGGGGGATATCGAAGTGGTTGCCAAAGCTATTCGGATAAAGGAGATTTTGACTAGTCAAGGCAGTTTAAG
CCATCCAAGCTTTGTTAGGCGGCTAAGGCGTTTAAAATGTCACGTTAGGGTTTTAGCAGCTGGAGACCAGTTGCCTATTA
TGGGAAGTGTCTTACAGGTACTCTACCCTTGGCAGTTAGGGGACGGGAAAAATAACGATTCTTTGGTACTTTATGGCAGG
CTCTTAAATCGAACTTTTCTTTTCACAGGTGACTTGGAAAAAGAGGGGGAAAACGAGATCATAAAACGTTATCCTCAACT
AAGAGTAGATTATTTAAAAGCAGGTCACCATGGATCAAATACCTCTTCTAGTGCAGCTTTTTTAGACCATATTCAGCCTA
AAGTGGCCTTTATTTCTGCTGGAAAAAATAACCGTTATCAGCATCCTCACAGAGAAACCTTAGCCCGTTTGGAAGACAGA
CAAATTACTTATTACCGAACGGATACGCAAGGAGCTATTCGTTTGACTGGTTGGACAAGCTGGCATCTTGAAACGGTCCG
TTAG

Domains

Predicted by InterProScan.

• Competence protein (Competence) (217-462)

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-701)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	46.185	100	0.462
comEC/celB	Streptococcus mitis NCTC 12261	45.979	99.866	0.459
comEC/celB	Streptococcus pneumoniae TIGR4	44.98	100	0.45
comEC/celB	Streptococcus pneumoniae Rx1	44.786	100	0.448
comEC/celB	Streptococcus pneumoniae D39	44.786	100	0.448
comEC/celB	Streptococcus pneumoniae R6	44.786	100	0.448
comEC	Lactococcus lactis subsp. cremoris KW2	40.403	99.732	0.403