Detailed information
Bioinformatically predicted
Overview
| Name | ciaH | Type | Regulator |
| Locus tag | SK637_RS03845 | Genome accession | NZ_CP028415 |
| Coordinates | 698124..699458 (+) | Length | 444 a.a. |
| NCBI ID | WP_033688608.1 | Uniprot ID | - |
| Organism | Streptococcus mitis strain SK637 | ||
| Function | repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation |
||
Genomic Context
Location: 693124..704458
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SK637_RS03825 | - | 693400..694301 (+) | 902 | Protein_679 | putative PEP-binding protein | - |
| SK637_RS03830 (SK637_00745) | - | 694243..694683 (+) | 441 | WP_033688605.1 | ASCH domain-containing protein | - |
| SK637_RS03835 (SK637_00746) | - | 694805..697351 (+) | 2547 | WP_033688607.1 | M1 family metallopeptidase | - |
| SK637_RS03840 (SK637_00747) | ciaR | 697460..698134 (+) | 675 | WP_000590639.1 | two-component system response regulator CiaR | Regulator |
| SK637_RS03845 (SK637_00748) | ciaH | 698124..699458 (+) | 1335 | WP_033688608.1 | two-component system sensor histidine kinase CiaH | Regulator |
| SK637_RS03850 (SK637_00749) | - | 699492..699779 (-) | 288 | WP_033688610.1 | DUF3270 domain-containing protein | - |
| SK637_RS03855 (SK637_00750) | - | 699919..700848 (+) | 930 | WP_033688612.1 | peptidase U32 family protein | - |
| SK637_RS03860 (SK637_00751) | - | 701048..703498 (+) | 2451 | WP_033688614.1 | bifunctional DnaQ family exonuclease/ATP-dependent helicase | - |
Sequence
Protein
Download Length: 444 a.a. Molecular weight: 50690.34 Da Isoelectric Point: 8.8716
>NTDB_id=284703 SK637_RS03845 WP_033688608.1 698124..699458(+) (ciaH) [Streptococcus mitis strain SK637]
MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLYTSVDDKLHGLSENPQAVIQLAVNRATEEIKDLENAA
TDTSKTDVKPNVSSNTEVILFDKNFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRMILMETNISSVSTN
IKYAAVLINTSQLEQASQKHEQLIVIVMASFWILSLLASLYLARVSVRPLLESMQKQQSFVENASHELRTPLAVLQNRLE
TLFRKPEATIMDVSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPELAEVPTSFFNTTFTNYEMIASENDRVFRFENRI
HRTIVTDQLLLKQLMTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGVGISTEDKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALKGTITVKDNKPKGTIFEVKIAIHTPSKKKK
MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLYTSVDDKLHGLSENPQAVIQLAVNRATEEIKDLENAA
TDTSKTDVKPNVSSNTEVILFDKNFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRMILMETNISSVSTN
IKYAAVLINTSQLEQASQKHEQLIVIVMASFWILSLLASLYLARVSVRPLLESMQKQQSFVENASHELRTPLAVLQNRLE
TLFRKPEATIMDVSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPELAEVPTSFFNTTFTNYEMIASENDRVFRFENRI
HRTIVTDQLLLKQLMTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGVGISTEDKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALKGTITVKDNKPKGTIFEVKIAIHTPSKKKK
Nucleotide
Download Length: 1335 bp
>NTDB_id=284703 SK637_RS03845 WP_033688608.1 698124..699458(+) (ciaH) [Streptococcus mitis strain SK637]
ATGTTCAGTAAACTAAAAAAAACATGGTATGCGGATGACTTTAGTTATTTTATCCGCAACTTTGGTGTCTTCACTCTGAT
TTTCTCTACCATGACTCTGATTATTTTGCAGGTCATGCATTCGAGTCTTTATACTTCGGTGGATGATAAGCTTCATGGAC
TGAGTGAAAATCCTCAAGCAGTTATTCAGCTTGCTGTAAATAGGGCAACAGAAGAGATTAAAGATTTAGAGAATGCTGCT
ACAGATACTAGTAAGACTGATGTGAAACCCAATGTCAGTTCCAACACAGAAGTCATTCTTTTTGATAAGAATTTTACCCA
GCTCCTTTCTGGAAACCGATTTTTGGGATTGGATAAGATTAAGTTAGAGAAAAAAGAACTAGGCCATATCTATCAGATTC
AAGTTTTTAATAGCTATGGACAAGAAGAAATTTATCGCATGATTTTGATGGAAACGAATATTAGTTCGGTTTCAACCAAT
ATCAAGTATGCGGCTGTCTTGATTAATACCAGTCAGTTGGAGCAGGCCAGTCAAAAGCATGAGCAATTGATTGTGATCGT
GATGGCAAGTTTCTGGATTTTGTCTTTGCTTGCCAGTCTCTATCTAGCTAGGGTCAGTGTTCGTCCTCTGCTTGAGAGCA
TGCAGAAGCAGCAGTCCTTTGTGGAAAATGCTAGTCATGAGTTACGAACTCCACTTGCAGTTTTGCAAAATCGCTTAGAG
ACCCTTTTCCGTAAGCCAGAAGCTACCATTATGGATGTGAGCGAAAGTATTGCATCTAGTTTGGAAGAAGTCCGAAATAT
GCGGTTTTTGACGACGAACTTGTTGAATTTGGCTCGTAGAGATGATGGGATTAAGCCTGAACTTGCTGAAGTTCCAACTA
GCTTTTTTAATACAACTTTCACAAACTATGAGATGATTGCTTCGGAAAATGATCGTGTCTTCCGTTTTGAAAATCGTATC
CATCGAACGATTGTCACAGATCAGCTCCTTTTGAAACAACTGATGACCATTCTATTTGATAATGCTGTTAAGTATACTGA
AGAGGATGGTGAAATTGATTTTCTTATCTCGGCGACCGATCGCAATCTGTATTTACTGGTTTCTGATAATGGAGTCGGTA
TTTCGACAGAAGATAAGAAGAAAATTTTTGACCGCTTTTATCGAGTGGACAAGGCTAGAACTCGTCAAAAAGGTGGTTTT
GGTTTAGGATTATCCCTAGCCAAGCAAATTGTAGATGCTTTAAAAGGAACCATTACTGTTAAAGATAATAAACCAAAGGG
AACAATCTTTGAAGTGAAGATTGCCATCCACACACCATCTAAAAAGAAAAAATAA
ATGTTCAGTAAACTAAAAAAAACATGGTATGCGGATGACTTTAGTTATTTTATCCGCAACTTTGGTGTCTTCACTCTGAT
TTTCTCTACCATGACTCTGATTATTTTGCAGGTCATGCATTCGAGTCTTTATACTTCGGTGGATGATAAGCTTCATGGAC
TGAGTGAAAATCCTCAAGCAGTTATTCAGCTTGCTGTAAATAGGGCAACAGAAGAGATTAAAGATTTAGAGAATGCTGCT
ACAGATACTAGTAAGACTGATGTGAAACCCAATGTCAGTTCCAACACAGAAGTCATTCTTTTTGATAAGAATTTTACCCA
GCTCCTTTCTGGAAACCGATTTTTGGGATTGGATAAGATTAAGTTAGAGAAAAAAGAACTAGGCCATATCTATCAGATTC
AAGTTTTTAATAGCTATGGACAAGAAGAAATTTATCGCATGATTTTGATGGAAACGAATATTAGTTCGGTTTCAACCAAT
ATCAAGTATGCGGCTGTCTTGATTAATACCAGTCAGTTGGAGCAGGCCAGTCAAAAGCATGAGCAATTGATTGTGATCGT
GATGGCAAGTTTCTGGATTTTGTCTTTGCTTGCCAGTCTCTATCTAGCTAGGGTCAGTGTTCGTCCTCTGCTTGAGAGCA
TGCAGAAGCAGCAGTCCTTTGTGGAAAATGCTAGTCATGAGTTACGAACTCCACTTGCAGTTTTGCAAAATCGCTTAGAG
ACCCTTTTCCGTAAGCCAGAAGCTACCATTATGGATGTGAGCGAAAGTATTGCATCTAGTTTGGAAGAAGTCCGAAATAT
GCGGTTTTTGACGACGAACTTGTTGAATTTGGCTCGTAGAGATGATGGGATTAAGCCTGAACTTGCTGAAGTTCCAACTA
GCTTTTTTAATACAACTTTCACAAACTATGAGATGATTGCTTCGGAAAATGATCGTGTCTTCCGTTTTGAAAATCGTATC
CATCGAACGATTGTCACAGATCAGCTCCTTTTGAAACAACTGATGACCATTCTATTTGATAATGCTGTTAAGTATACTGA
AGAGGATGGTGAAATTGATTTTCTTATCTCGGCGACCGATCGCAATCTGTATTTACTGGTTTCTGATAATGGAGTCGGTA
TTTCGACAGAAGATAAGAAGAAAATTTTTGACCGCTTTTATCGAGTGGACAAGGCTAGAACTCGTCAAAAAGGTGGTTTT
GGTTTAGGATTATCCCTAGCCAAGCAAATTGTAGATGCTTTAAAAGGAACCATTACTGTTAAAGATAATAAACCAAAGGG
AACAATCTTTGAAGTGAAGATTGCCATCCACACACCATCTAAAAAGAAAAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ciaH | Streptococcus pneumoniae Rx1 |
96.622 |
100 |
0.966 |
| ciaH | Streptococcus pneumoniae D39 |
96.622 |
100 |
0.966 |
| ciaH | Streptococcus pneumoniae R6 |
96.622 |
100 |
0.966 |
| ciaH | Streptococcus pneumoniae TIGR4 |
96.622 |
100 |
0.966 |
| ciaH | Streptococcus mutans UA159 |
55.632 |
97.973 |
0.545 |