Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   SK637_RS00095 Genome accession   NZ_CP028415
Coordinates   20591..20827 (+) Length   78 a.a.
NCBI ID   WP_033687874.1    Uniprot ID   A0A1T0C2F0
Organism   Streptococcus mitis strain SK637     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 15591..25827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SK637_RS00095 (SK637_00020) comW 20591..20827 (+) 237 WP_033687874.1 sigma(X)-activator ComW Regulator
  SK637_RS00100 (SK637_00021) - 21058..22344 (+) 1287 WP_001832534.1 adenylosuccinate synthase -
  SK637_RS00105 (SK637_00022) tadA 22544..23011 (+) 468 WP_033687875.1 tRNA adenosine(34) deaminase TadA -
  SK637_RS00115 (SK637_00023) - 23198..23641 (+) 444 WP_000701983.1 dUTP diphosphatase -
  SK637_RS00120 (SK637_00024) - 23643..24182 (+) 540 WP_033687876.1 histidine phosphatase family protein -
  SK637_RS00125 - 24193..24354 (+) 162 Protein_19 DNA repair protein RadA -
  SK637_RS00130 (SK637_00025) - 24350..24652 (+) 303 Protein_20 isochorismatase family protein -
  SK637_RS00135 (SK637_00026) - 24671..25186 (+) 516 WP_033687877.1 histidine phosphatase family protein -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9841.19 Da        Isoelectric Point: 6.4720

>NTDB_id=284669 SK637_RS00095 WP_033687874.1 20591..20827(+) (comW) [Streptococcus mitis strain SK637]
MLQSIYNQMTDFYNSIEEEYATFFGDSWDWEHFHFKFLIYYLFRYSIGSHRDFIVYHYRVAYRLYLEKLIMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=284669 SK637_RS00095 WP_033687874.1 20591..20827(+) (comW) [Streptococcus mitis strain SK637]
ATGCTACAAAGTATTTATAATCAGATGACAGATTTCTATAACAGTATCGAAGAAGAGTATGCTACTTTCTTTGGTGATAG
TTGGGACTGGGAACATTTTCATTTTAAATTTTTGATTTATTATCTTTTCCGATATAGCATTGGGAGCCATCGGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGATAATGAATCGGGGATTTATTTCGTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1T0C2F0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

78.205

100

0.782
  comW Streptococcus pneumoniae D39

78.205

100

0.782
  comW Streptococcus pneumoniae R6

78.205

100

0.782
  comW Streptococcus pneumoniae TIGR4

78.205

100

0.782
  comW Streptococcus mitis SK321

78.205

100

0.782
  comW Streptococcus mitis NCTC 12261

77.922

98.718

0.769

Multiple sequence alignment