Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   EB818_RS00675 Genome accession   NZ_CP033335
Coordinates   104232..104660 (+) Length   142 a.a.
NCBI ID   WP_076639399.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY208     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99232..109660
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EB818_RS00655 (EB818_00655) - 101563..101928 (+) 366 WP_002986560.1 DUF1033 family protein -
  EB818_RS00660 (EB818_00660) comGA 102021..102959 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  EB818_RS00665 (EB818_00665) comGB 102895..103929 (+) 1035 WP_228631569.1 competence type IV pilus assembly protein ComGB Machinery gene
  EB818_RS00670 (EB818_00670) comGC 103931..104257 (+) 327 WP_011528161.1 competence type IV pilus major pilin ComGC Machinery gene
  EB818_RS00675 (EB818_00675) comGD 104232..104660 (+) 429 WP_076639399.1 competence type IV pilus minor pilin ComGD Machinery gene
  EB818_RS00680 (EB818_00680) comGE 104617..104901 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  EB818_RS00685 (EB818_00685) comGF 104894..105328 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  EB818_RS00690 (EB818_00690) comGG 105312..105638 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  EB818_RS00695 (EB818_00695) comGH 105736..106689 (+) 954 WP_129322573.1 class I SAM-dependent methyltransferase Machinery gene
  EB818_RS00700 (EB818_00700) - 106748..107944 (+) 1197 WP_020904834.1 acetate kinase -
  EB818_RS00705 (EB818_00705) - 108131..108439 (+) 309 Protein_88 hypothetical protein -
  EB818_RS00710 (EB818_00710) proC 108522..109292 (-) 771 WP_076639397.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16338.09 Da        Isoelectric Point: 10.3481

>NTDB_id=282953 EB818_RS00675 WP_076639399.1 104232..104660(+) (comGD) [Streptococcus pyogenes strain TSPY208]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLVKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=282953 EB818_RS00675 WP_076639399.1 104232..104660(+) (comGD) [Streptococcus pyogenes strain TSPY208]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGTTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

39.706

95.775

0.38
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373

Multiple sequence alignment