Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   HSM_RS00020 Genome accession   NC_010519
Coordinates   3895..4539 (-) Length   214 a.a.
NCBI ID   WP_011608291.1    Uniprot ID   -
Organism   Histophilus somni 2336     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1..9539
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSM_RS00005 (HSM_0001) dnaA 288..1646 (+) 1359 WP_041604945.1 chromosomal replication initiator protein DnaA -
  HSM_RS00010 (HSM_0002) dnaN 1658..2758 (+) 1101 WP_011608289.1 DNA polymerase III subunit beta -
  HSM_RS00015 (HSM_0003) recF 2762..3838 (+) 1077 WP_012341166.1 DNA replication/repair protein RecF -
  HSM_RS00020 (HSM_0004) crp 3895..4539 (-) 645 WP_011608291.1 cAMP-activated global transcriptional regulator CRP Regulator
  HSM_RS00025 (HSM_0005) - 4552..4776 (-) 225 WP_012341336.1 YheU family protein -
  HSM_RS00030 (HSM_0006) slmA 4811..5470 (-) 660 WP_011608293.1 nucleoid occlusion factor SlmA -
  HSM_RS00035 (HSM_0007) dut 5470..5925 (-) 456 WP_011608294.1 dUTP diphosphatase -
  HSM_RS00040 (HSM_0008) coaBC 5922..7148 (-) 1227 WP_012341613.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  HSM_RS00045 (HSM_0009) radC 7321..7989 (+) 669 WP_011608296.1 DNA repair protein RadC Machinery gene
  HSM_RS00050 (HSM_0010) rpmB 8210..8446 (+) 237 WP_011608297.1 50S ribosomal protein L28 -
  HSM_RS00055 (HSM_0011) rpmG 8458..8628 (+) 171 WP_005542835.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24029.75 Da        Isoelectric Point: 7.4775

>NTDB_id=28051 HSM_RS00020 WP_011608291.1 3895..4539(-) (crp) [Histophilus somni 2336]
MLEQQGQSAPSMDPTLEWFLSHCHIHKYSAKSSLIHAGEKAETLYYLIRGSVAVMVKDEEGKEMILTYLSQGDFFGEAGL
FDETQPRSAWVKAKSSCEIAEISYKKFRQLIQVNPEILMYLAGQLAHRLQNTSKQVSNLAFLDVTGRIAQTLLNLAKMPD
AMTHPDGMQIKITRQEIGQMVGCSRETVGRILKMLEDQHLISAHGKTIVVYGTR

Nucleotide


Download         Length: 645 bp        

>NTDB_id=28051 HSM_RS00020 WP_011608291.1 3895..4539(-) (crp) [Histophilus somni 2336]
ATGTTAGAACAACAAGGACAATCAGCACCATCGATGGATCCGACGTTAGAGTGGTTCCTATCTCATTGTCACATTCATAA
ATACTCAGCAAAAAGCTCCCTCATTCATGCTGGAGAAAAGGCGGAAACCCTTTATTATTTAATTAGAGGGTCTGTTGCCG
TGATGGTAAAAGATGAGGAAGGTAAAGAAATGATTTTGACTTATTTAAGTCAAGGTGATTTTTTTGGCGAAGCTGGTTTA
TTTGATGAAACACAGCCTCGTTCGGCTTGGGTTAAAGCTAAAAGCTCATGTGAAATTGCAGAAATTTCTTATAAAAAATT
TCGCCAATTAATTCAAGTTAATCCAGAAATTTTAATGTATTTAGCCGGTCAATTAGCTCATCGTTTACAAAATACTTCAA
AGCAGGTAAGCAATTTGGCATTTTTAGATGTGACAGGTCGTATCGCTCAAACCTTGTTAAATTTAGCTAAGATGCCTGAT
GCAATGACTCATCCGGACGGTATGCAAATTAAAATTACTCGTCAGGAAATAGGACAAATGGTAGGTTGCTCACGAGAAAC
TGTTGGGCGTATTTTGAAAATGTTAGAAGATCAGCATTTAATTTCAGCACATGGCAAAACTATTGTTGTGTATGGTACAA
GATAA

Domains

Predicted by InterProScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(146-210)

Cyclic nucleotide-binding domain (cNMP_binding)

(27-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

81.463

95.794

0.78
  crp Haemophilus influenzae Rd KW20

78.846

97.196

0.766
  crp Acinetobacter baumannii D1279779

44.221

92.991

0.411

Multiple sequence alignment