Detailed information NTG0277921

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: SPV_RS04645
• Genome accession: NZ_CP027540
• Coordinates: 879655..880608 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain D39V
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 874655..885608

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPV_RS04620 (SPV_2259)	rpmG	875398..875547 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
SPV_RS04625 (SPV_0861)	secG	875587..875820 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
SPV_RS04630 (SPV_0862)	rnr	875922..878276 (+)	2355	WP_000654897.1	ribonuclease R	-
SPV_RS04635 (SPV_0863)	smpB	878239..878706 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
SPV_RS04640 (SPV_0864)	tehB	878722..879582 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
SPV_RS04645 (SPV_0865)	coiA	879655..880608 (+)	954	WP_000495911.1	competence protein CoiA	Machinery gene
SPV_RS04650 (SPV_0866)	pepF	880627..882429 (+)	1803	WP_000244122.1	oligoendopeptidase F	Regulator
SPV_RS04655 (SPV_0867)	-	882431..883144 (+)	714	WP_000230399.1	O-methyltransferase	-
SPV_RS04660 (SPV_0868)	prsA	883211..884152 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
SPV_RS04665 (SPV_2260)	-	884271..884612 (-)	342	Protein_882	transposase	-
SPV_RS04675	-	885024..885119 (+)	96	Protein_883	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=277921 SPV_RS04645 WP_000495911.1 879655..880608(+) (coiA) [Streptococcus pneumoniae strain D39V]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=277921 SPV_RS04645 WP_000495911.1 879655..880608(+) (coiA) [Streptococcus pneumoniae strain D39V]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435