Detailed information
Bioinformatically predicted
Overview
| Name | ciaH | Type | Regulator |
| Locus tag | SSA_RS04750 | Genome accession | NC_009009 |
| Coordinates | 968646..970037 (+) | Length | 463 a.a. |
| NCBI ID | WP_002904314.1 | Uniprot ID | A0A2X4AJ38 |
| Organism | Streptococcus sanguinis SK36 | ||
| Function | repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 955095..978388 | 968646..970037 | within | 0 |
Gene organization within MGE regions
Location: 955095..978388
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SSA_RS04695 (SSA_0949) | - | 955817..956455 (+) | 639 | WP_002917398.1 | hypothetical protein | - |
| SSA_RS04700 (SSA_0950) | - | 956442..957848 (+) | 1407 | WP_002917397.1 | hypothetical protein | - |
| SSA_RS04705 (SSA_0952) | - | 957859..958155 (+) | 297 | WP_011836821.1 | hypothetical protein | - |
| SSA_RS04710 (SSA_0954) | - | 958164..958490 (+) | 327 | WP_002934028.1 | hypothetical protein | - |
| SSA_RS04715 (SSA_0955) | - | 958659..961199 (+) | 2541 | WP_011836822.1 | M1 family metallopeptidase | - |
| SSA_RS04720 (SSA_0956) | - | 961363..965478 (+) | 4116 | WP_011836823.1 | GbpC/Spa domain-containing protein | - |
| SSA_RS04725 | - | 965746..966030 (+) | 285 | WP_002900560.1 | helix-turn-helix domain-containing protein | - |
| SSA_RS04730 | - | 966086..966412 (+) | 327 | WP_002900559.1 | DMT family transporter | - |
| SSA_RS04735 (SSA_0957) | - | 966416..967231 (+) | 816 | WP_011836824.1 | SDR family NAD(P)-dependent oxidoreductase | - |
| SSA_RS04740 (SSA_0958) | - | 967413..967877 (+) | 465 | WP_011836825.1 | hypothetical protein | - |
| SSA_RS04745 (SSA_0959) | ciaR | 967982..968656 (+) | 675 | WP_002897753.1 | response regulator transcription factor | Regulator |
| SSA_RS04750 (SSA_0960) | ciaH | 968646..970037 (+) | 1392 | WP_002904314.1 | sensor histidine kinase | Regulator |
| SSA_RS04755 (SSA_0961) | - | 970053..970991 (+) | 939 | WP_011836826.1 | ketopantoate reductase family protein | - |
| SSA_RS04760 (SSA_0962) | - | 971105..971491 (+) | 387 | WP_002895748.1 | VOC family protein | - |
| SSA_RS04765 (SSA_0963) | - | 971553..972950 (+) | 1398 | WP_011836827.1 | polysaccharide deacetylase family protein | - |
| SSA_RS04770 (SSA_0964) | - | 973044..974135 (-) | 1092 | WP_033179140.1 | DEAD/DEAH box helicase | - |
| SSA_RS04775 (SSA_0965) | - | 974125..975135 (-) | 1011 | WP_011836829.1 | Gfo/Idh/MocA family protein | - |
| SSA_RS04780 (SSA_0966) | udk | 975215..975850 (+) | 636 | WP_032909529.1 | uridine kinase | - |
| SSA_RS04785 (SSA_0967) | - | 976012..976680 (+) | 669 | WP_011836830.1 | YoaK family protein | - |
| SSA_RS04790 (SSA_0968) | - | 976764..977201 (+) | 438 | WP_398578193.1 | hypothetical protein | - |
| SSA_RS04795 (SSA_0969) | - | 977352..977789 (+) | 438 | WP_011836832.1 | hypothetical protein | - |
| SSA_RS04800 (SSA_0970) | - | 977930..978388 (+) | 459 | WP_011836833.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 463 a.a. Molecular weight: 52603.01 Da Isoelectric Point: 8.4934
>NTDB_id=27522 SSA_RS04750 WP_002904314.1 968646..970037(+) (ciaH) [Streptococcus sanguinis SK36]
MLNKIKKTFYADDFSYFIRYFGLFTLIFSAMTLIIIQVMRSSLYTSVDENLKNLSNDPSSVADLAYRTTGQQSDPSNKVN
SKSPKSSKEPDGDSDEEPKPNNLTTPNVSSNTFALLLDDDYKNISTSKSDGFLDFNSLEFNKSYLNQIKEIVIGNSFGQT
ESYRAYLFDIDPKNEYPDIKYAVVMTSISQLEQTSSKHEQLIAMVMVSFWGISLIASIYLARMSVKPLLESIQKQKAFVE
NASHELRTPLAVLQSRLETLFRKPEATIMQSSENIASSLDEVRNMRLLTTNLLNLARRDDGIKPQYGEVEPEFFDTTFAN
YCIIARENKKAFHSENMIKHPIVTDQIFLKQLMTILFDNAIKYTDDDGVISVMATSTDRYLIFRVADNGPGISDEDKKKI
FDRFYRVDKARTRQKGGFGLGLSLAKQIVDAFKGSIYVKDNKPKGTVFEVKLLLKETKKRSVK
MLNKIKKTFYADDFSYFIRYFGLFTLIFSAMTLIIIQVMRSSLYTSVDENLKNLSNDPSSVADLAYRTTGQQSDPSNKVN
SKSPKSSKEPDGDSDEEPKPNNLTTPNVSSNTFALLLDDDYKNISTSKSDGFLDFNSLEFNKSYLNQIKEIVIGNSFGQT
ESYRAYLFDIDPKNEYPDIKYAVVMTSISQLEQTSSKHEQLIAMVMVSFWGISLIASIYLARMSVKPLLESIQKQKAFVE
NASHELRTPLAVLQSRLETLFRKPEATIMQSSENIASSLDEVRNMRLLTTNLLNLARRDDGIKPQYGEVEPEFFDTTFAN
YCIIARENKKAFHSENMIKHPIVTDQIFLKQLMTILFDNAIKYTDDDGVISVMATSTDRYLIFRVADNGPGISDEDKKKI
FDRFYRVDKARTRQKGGFGLGLSLAKQIVDAFKGSIYVKDNKPKGTVFEVKLLLKETKKRSVK
Nucleotide
Download Length: 1392 bp
>NTDB_id=27522 SSA_RS04750 WP_002904314.1 968646..970037(+) (ciaH) [Streptococcus sanguinis SK36]
ATGCTGAATAAAATCAAGAAGACCTTTTATGCGGATGATTTCTCTTATTTCATTCGCTATTTTGGGTTGTTTACATTAAT
CTTCTCAGCCATGACCTTGATTATTATTCAGGTTATGCGCTCCAGCCTTTATACGTCAGTTGATGAAAATCTGAAAAACC
TGAGTAATGATCCTAGTTCAGTAGCTGATTTGGCCTATCGGACGACAGGTCAGCAGTCTGATCCGAGCAATAAGGTCAAT
TCTAAAAGTCCTAAAAGCAGTAAAGAGCCAGATGGCGATTCAGATGAAGAGCCTAAGCCTAACAATCTAACTACGCCAAA
TGTTAGCTCTAATACCTTTGCCTTGCTTTTGGATGATGATTATAAAAATATTTCCACCAGCAAGAGCGATGGTTTTCTGG
ACTTTAATTCATTAGAGTTTAACAAGTCCTATCTGAATCAAATCAAGGAAATTGTGATTGGCAACAGCTTTGGTCAGACA
GAAAGTTATCGGGCTTATCTCTTTGATATTGATCCTAAAAATGAGTACCCTGATATCAAGTACGCTGTGGTCATGACTAG
TATCAGCCAGCTAGAGCAGACCAGCAGCAAGCATGAGCAGTTGATTGCCATGGTCATGGTCAGCTTTTGGGGAATTTCCC
TGATTGCCAGTATTTACCTTGCTCGGATGAGTGTCAAGCCTCTGCTGGAAAGTATCCAGAAGCAGAAGGCTTTCGTGGAA
AATGCCAGTCACGAGCTACGGACTCCTCTGGCAGTATTGCAGAGCCGCTTAGAGACGCTCTTTCGTAAGCCTGAAGCTAC
AATCATGCAGAGCAGTGAAAATATTGCTTCTAGCTTGGATGAAGTACGCAATATGCGCTTGCTGACGACCAATCTGCTCA
ATCTGGCTCGTCGCGATGATGGCATCAAACCTCAATATGGTGAAGTCGAACCAGAATTTTTTGATACGACCTTTGCTAAT
TACTGTATTATCGCAAGGGAGAATAAAAAAGCCTTTCATTCAGAAAATATGATTAAGCACCCTATTGTGACCGATCAAAT
TTTTCTCAAACAACTGATGACCATTCTATTTGACAATGCTATCAAGTATACAGATGATGATGGCGTAATCAGTGTCATGG
CTACTTCGACAGATCGCTACCTTATTTTCCGAGTGGCGGACAATGGTCCTGGTATCAGCGATGAAGATAAGAAGAAGATT
TTTGATCGCTTTTATCGGGTGGACAAGGCTCGGACCCGTCAGAAAGGTGGCTTTGGTCTGGGACTTTCTTTGGCCAAGCA
GATTGTCGATGCTTTCAAAGGCTCTATTTATGTCAAGGACAACAAACCAAAAGGTACGGTCTTTGAAGTTAAACTGCTCC
TGAAAGAAACGAAAAAGCGTTCTGTTAAATAG
ATGCTGAATAAAATCAAGAAGACCTTTTATGCGGATGATTTCTCTTATTTCATTCGCTATTTTGGGTTGTTTACATTAAT
CTTCTCAGCCATGACCTTGATTATTATTCAGGTTATGCGCTCCAGCCTTTATACGTCAGTTGATGAAAATCTGAAAAACC
TGAGTAATGATCCTAGTTCAGTAGCTGATTTGGCCTATCGGACGACAGGTCAGCAGTCTGATCCGAGCAATAAGGTCAAT
TCTAAAAGTCCTAAAAGCAGTAAAGAGCCAGATGGCGATTCAGATGAAGAGCCTAAGCCTAACAATCTAACTACGCCAAA
TGTTAGCTCTAATACCTTTGCCTTGCTTTTGGATGATGATTATAAAAATATTTCCACCAGCAAGAGCGATGGTTTTCTGG
ACTTTAATTCATTAGAGTTTAACAAGTCCTATCTGAATCAAATCAAGGAAATTGTGATTGGCAACAGCTTTGGTCAGACA
GAAAGTTATCGGGCTTATCTCTTTGATATTGATCCTAAAAATGAGTACCCTGATATCAAGTACGCTGTGGTCATGACTAG
TATCAGCCAGCTAGAGCAGACCAGCAGCAAGCATGAGCAGTTGATTGCCATGGTCATGGTCAGCTTTTGGGGAATTTCCC
TGATTGCCAGTATTTACCTTGCTCGGATGAGTGTCAAGCCTCTGCTGGAAAGTATCCAGAAGCAGAAGGCTTTCGTGGAA
AATGCCAGTCACGAGCTACGGACTCCTCTGGCAGTATTGCAGAGCCGCTTAGAGACGCTCTTTCGTAAGCCTGAAGCTAC
AATCATGCAGAGCAGTGAAAATATTGCTTCTAGCTTGGATGAAGTACGCAATATGCGCTTGCTGACGACCAATCTGCTCA
ATCTGGCTCGTCGCGATGATGGCATCAAACCTCAATATGGTGAAGTCGAACCAGAATTTTTTGATACGACCTTTGCTAAT
TACTGTATTATCGCAAGGGAGAATAAAAAAGCCTTTCATTCAGAAAATATGATTAAGCACCCTATTGTGACCGATCAAAT
TTTTCTCAAACAACTGATGACCATTCTATTTGACAATGCTATCAAGTATACAGATGATGATGGCGTAATCAGTGTCATGG
CTACTTCGACAGATCGCTACCTTATTTTCCGAGTGGCGGACAATGGTCCTGGTATCAGCGATGAAGATAAGAAGAAGATT
TTTGATCGCTTTTATCGGGTGGACAAGGCTCGGACCCGTCAGAAAGGTGGCTTTGGTCTGGGACTTTCTTTGGCCAAGCA
GATTGTCGATGCTTTCAAAGGCTCTATTTATGTCAAGGACAACAAACCAAAAGGTACGGTCTTTGAAGTTAAACTGCTCC
TGAAAGAAACGAAAAAGCGTTCTGTTAAATAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ciaH | Streptococcus pneumoniae Rx1 |
60.738 |
99.568 |
0.605 |
| ciaH | Streptococcus pneumoniae D39 |
60.738 |
99.568 |
0.605 |
| ciaH | Streptococcus pneumoniae R6 |
60.738 |
99.568 |
0.605 |
| ciaH | Streptococcus pneumoniae TIGR4 |
60.738 |
99.568 |
0.605 |
| ciaH | Streptococcus mutans UA159 |
53.289 |
98.488 |
0.525 |