Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   SSA_RS03260 Genome accession   NC_009009
Coordinates   629481..630143 (-) Length   220 a.a.
NCBI ID   WP_011836640.1    Uniprot ID   A3CLM6
Organism   Streptococcus sanguinis SK36     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 624481..635143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS03230 (SSA_0635) trpC 624528..625295 (+) 768 WP_011836635.1 indole-3-glycerol phosphate synthase TrpC -
  SSA_RS03235 (SSA_0636) - 625282..625869 (+) 588 WP_033179124.1 phosphoribosylanthranilate isomerase -
  SSA_RS03240 (SSA_0637) trpB 625859..627082 (+) 1224 WP_011836637.1 tryptophan synthase subunit beta -
  SSA_RS03245 (SSA_0638) trpA 627075..627854 (+) 780 WP_011836638.1 tryptophan synthase subunit alpha -
  SSA_RS03250 (SSA_0640) - 628060..628959 (-) 900 WP_002898048.1 helix-turn-helix transcriptional regulator -
  SSA_RS03255 (SSA_0641) - 629038..629487 (+) 450 WP_011836639.1 effector binding domain-containing protein -
  SSA_RS03260 (SSA_0642) cclA/cilC 629481..630143 (-) 663 WP_011836640.1 prepilin peptidase Machinery gene
  SSA_RS03265 (SSA_0644) - 630310..630825 (+) 516 WP_002911956.1 Dps family protein -
  SSA_RS03270 (SSA_0646) - 630918..631136 (+) 219 WP_002898045.1 YqgQ family protein -
  SSA_RS03275 (SSA_0647) - 631138..631518 (+) 381 WP_011836641.1 rhodanese-like domain-containing protein -
  SSA_RS03280 (SSA_0648) - 631608..631835 (+) 228 WP_011836642.1 hypothetical protein -
  SSA_RS03285 (SSA_0649) - 631910..632635 (-) 726 WP_011836643.1 pseudouridine synthase -
  SSA_RS03290 (SSA_0650) typA 632817..634664 (+) 1848 WP_033179125.1 translational GTPase TypA -
  SSA_RS03295 (SSA_0651) - 634688..634957 (+) 270 WP_002898040.1 DUF3165 family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24702.98 Da        Isoelectric Point: 8.7481

>NTDB_id=27512 SSA_RS03260 WP_011836640.1 629481..630143(-) (cclA/cilC) [Streptococcus sanguinis SK36]
MIHLYLFIIGTVFASFLGLVIDRFPEQSIITPASHCNACGKRLAPRDLIPIFSQVMNRLRCRFCGDKIPLRYLFFESILG
GLFLASSLGTISISQLLLLTMGLTLAIYDQREQQYPLMVWLVFHLLLIVTASINLLMLFFLALGLLAFFCNLRIGAGDFL
FLASCSAIFSLTEILILIQIASFAGLACFCFKKKKDRLAFVPCLLFGVVVIISYKSLLFY

Nucleotide


Download         Length: 663 bp        

>NTDB_id=27512 SSA_RS03260 WP_011836640.1 629481..630143(-) (cclA/cilC) [Streptococcus sanguinis SK36]
ATGATTCATCTATACTTATTTATTATTGGCACTGTCTTTGCCTCATTCCTAGGCTTGGTCATAGACCGCTTTCCAGAGCA
GTCTATCATCACCCCAGCTAGTCATTGCAATGCCTGCGGGAAAAGGTTGGCACCGCGTGATTTGATTCCTATTTTTTCCC
AAGTCATGAACCGGCTTCGTTGCCGCTTCTGCGGAGACAAGATTCCCTTACGCTATTTATTTTTTGAATCTATCTTGGGC
GGTCTTTTTCTGGCATCCTCACTTGGCACGATTTCCATCAGTCAACTCCTACTACTCACCATGGGCTTGACCCTAGCCAT
CTACGATCAAAGAGAGCAGCAATATCCCCTGATGGTCTGGTTGGTTTTTCATCTCTTGCTGATAGTGACAGCGAGCATCA
ACCTTCTCATGCTCTTCTTTTTAGCCCTAGGACTTCTGGCCTTCTTTTGTAATCTTCGTATTGGAGCTGGCGACTTTCTA
TTCCTTGCTTCCTGCTCAGCCATTTTCAGTCTGACGGAAATTCTCATTCTTATCCAAATCGCTAGCTTCGCTGGTCTCGC
CTGTTTTTGCTTTAAAAAGAAAAAAGACAGGCTGGCATTTGTACCCTGTCTTTTGTTTGGTGTGGTGGTGATTATTTCTT
ATAAATCCCTACTCTTTTACTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-86)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3CLM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis NCTC 12261

60.092

99.091

0.595
  cclA/cilC Streptococcus mitis SK321

59.174

99.091

0.586
  cclA/cilC Streptococcus pneumoniae Rx1

58.716

99.091

0.582
  cclA/cilC Streptococcus pneumoniae D39

58.716

99.091

0.582
  cclA/cilC Streptococcus pneumoniae R6

58.716

99.091

0.582
  cclA/cilC Streptococcus pneumoniae TIGR4

57.339

99.091

0.568

Multiple sequence alignment