Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   C5S64_RS02060 Genome accession   NZ_CP027027
Coordinates   372873..373997 (-) Length   374 a.a.
NCBI ID   WP_000228549.1    Uniprot ID   -
Organism   Shigella dysenteriae strain E670/74     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 367873..378997
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C5S64_RS02030 - 369672..370227 (+) 556 Protein_368 gamma carbonic anhydrase family protein -
  C5S64_RS02035 - 370203..370460 (-) 258 WP_001070563.1 DUF1488 domain-containing protein -
  C5S64_RS02040 aroE 370457..371275 (-) 819 WP_000451217.1 shikimate dehydrogenase -
  C5S64_RS02045 tsaC 371280..371852 (-) 573 WP_004967107.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  C5S64_RS02050 - 371857..372399 (-) 543 WP_001129725.1 type I DNA topoisomerase -
  C5S64_RS02055 smg 372428..372901 (-) 474 WP_105241793.1 DUF494 family protein Smg -
  C5S64_RS02060 dprA 372873..373997 (-) 1125 WP_000228549.1 DNA-protecting protein DprA Machinery gene
  C5S64_RS02065 def 374127..374636 (+) 510 WP_000114984.1 peptide deformylase -
  C5S64_RS02070 fmt 374651..375598 (+) 948 WP_000004436.1 methionyl-tRNA formyltransferase -
  C5S64_RS02075 rsmB 375644..376933 (+) 1290 WP_004967100.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  C5S64_RS02080 trkA 376955..378331 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  C5S64_RS02085 mscL 378461..378871 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40963.92 Da        Isoelectric Point: 6.2655

>NTDB_id=274553 C5S64_RS02060 WP_000228549.1 372873..373997(-) (dprA) [Shigella dysenteriae strain E670/74]
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=274553 C5S64_RS02060 WP_000228549.1 372873..373997(-) (dprA) [Shigella dysenteriae strain E670/74]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTTTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Glaesserella parasuis strain SC1401

45.401

90.107

0.409
  dprA Vibrio cholerae strain A1552

49.355

82.888

0.409
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393

Multiple sequence alignment