Detailed information NTG0272147

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: D1104_RS10720
• Genome accession: NZ_CP031863
• Coordinates: 2248480..2249154 (-)
• Length: 224 a.a.
• NCBI ID: WP_005599747.1
• Uniprot ID: -
• Organism: Actinobacillus pleuropneumoniae serovar 11 str. 56153
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2243480..2254154

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1104_RS10690 (D1104_10745)	adhP	2243582..2244631 (+)	1050	WP_237606047.1	alcohol dehydrogenase AdhP	-
D1104_RS10695 (D1104_10750)	miaA	2244763..2245707 (+)	945	WP_005618608.1	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	-
D1104_RS10700 (D1104_10755)	hfq	2245772..2246050 (+)	279	WP_005599741.1	RNA chaperone Hfq	-
D1104_RS10705 (D1104_10760)	hflX	2246088..2247449 (+)	1362	WP_080550267.1	ribosome rescue GTPase HflX	-
D1104_RS10710 (D1104_10765)	-	2247485..2248045 (-)	561	WP_005599745.1	TIGR00730 family Rossman fold protein	-
D1104_RS10715 (D1104_10770)	-	2248108..2248431 (+)	324	WP_005599746.1	MazG nucleotide pyrophosphohydrolase domain-containing protein	-
D1104_RS10720 (D1104_10775)	crp	2248480..2249154 (-)	675	WP_005599747.1	cAMP-activated global transcriptional regulator CRP	Regulator
D1104_RS10725 (D1104_10780)	-	2249232..2249450 (-)	219	WP_005599748.1	YheU family protein	-
D1104_RS10730 (D1104_10785)	slmA	2249456..2250064 (-)	609	WP_005620316.1	nucleoid occlusion factor SlmA	-
D1104_RS10735 (D1104_10790)	dut	2250170..2250625 (-)	456	WP_005599752.1	dUTP diphosphatase	-
D1104_RS10740 (D1104_10795)	coaBC	2250634..2251839 (-)	1206	WP_005602882.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
D1104_RS10745 (D1104_10800)	radC	2252047..2252709 (+)	663	WP_005599756.1	RadC family protein	Machinery gene
D1104_RS10750 (D1104_10805)	rpmB	2252878..2253114 (+)	237	WP_005599762.1	50S ribosomal protein L28	-
D1104_RS10755 (D1104_10810)	rpmG	2253126..2253296 (+)	171	WP_005599764.1	50S ribosomal protein L33	-
D1104_RS10760	-	2253422..2253640 (+)	219	WP_162031030.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25147.02 Da
• Isoelectric Point: 6.5834

>NTDB_id=272147 D1104_RS10720 WP_005599747.1 2248480..2249154(-) (crp) [Actinobacillus pleuropneumoniae serovar 11 str. 56153]
MQDISISTPQLDSELSAPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEDAESLFYIVSGSVAVFIKDEEGKEMILSHLGQ
GEFVGEISLFEDTIQPRTAWVKTKGACEIAEISYKKFKQLVHLNPDILMYLSAQMARRLRQTSRQVSNLAFLDVTGRIAQ
TLMNLAKMPDAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide

• Length: 675 bp

>NTDB_id=272147 D1104_RS10720 WP_005599747.1 2248480..2249154(-) (crp) [Actinobacillus pleuropneumoniae serovar 11 str. 56153]
ATGCAAGATATTTCAATTTCAACACCTCAGCTAGACAGTGAGCTGTCCGCCCCGTCTATTCATGATCCGGCGGTGGAATG
GTTTCTGACTCACTGTCATATTCATCGTTATCCGTCAAAATATACGCTTATTCATGCGGGTGAGGATGCCGAATCATTAT
TCTATATCGTCAGCGGCTCCGTTGCAGTGTTTATTAAAGATGAAGAAGGGAAAGAAATGATCCTTTCTCACCTCGGTCAA
GGTGAATTTGTCGGTGAAATCAGCTTATTTGAAGACACTATTCAACCGCGTACCGCTTGGGTCAAAACCAAAGGCGCTTG
CGAAATTGCGGAAATCTCGTATAAAAAATTCAAACAGCTTGTGCATTTAAATCCGGATATTCTTATGTATCTTTCCGCGC
AAATGGCTCGCCGCCTACGCCAAACCTCACGCCAAGTAAGTAACCTCGCTTTCTTAGACGTAACCGGTCGTATCGCACAA
ACCTTAATGAATTTGGCGAAAATGCCGGATGCGATGACCCATCCGGAAGGAATGCAAATTAAGATTACCCGCCAAGAAAT
CGGTCAAATGGTCGGTTGTTCTCGAGAAACGGTCGGTAGAATCTTAAAAATGCTAGAAGATGAAGGCTTAATTTCAGCAC
ACGGTAAAACCATTGTCGTTTATGGCACTCGCTAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

• Cyclic nucleotide-binding domain (cNMP_binding) (36-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	77.34	90.625	0.701
crp	Haemophilus influenzae Rd KW20	73.892	90.625	0.67
crp	Acinetobacter baumannii D1279779	45.794	95.536	0.437