Detailed information NTG0272092

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: D1105_RS10245
• Genome accession: NZ_CP031862
• Coordinates: 2175416..2176090 (-)
• Length: 224 a.a.
• NCBI ID: WP_005599747.1
• Uniprot ID: -
• Organism: Actinobacillus pleuropneumoniae strain 8329
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2170416..2181090

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1105_RS10215 (D1105_10290)	adhP	2170512..2171561 (+)	1050	WP_005602862.1	alcohol dehydrogenase AdhP	-
D1105_RS10220 (D1105_10295)	miaA	2171693..2172637 (+)	945	WP_043995181.1	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	-
D1105_RS10225 (D1105_10300)	hfq	2172702..2172980 (+)	279	WP_005616337.1	RNA chaperone Hfq	-
D1105_RS10230 (D1105_10305)	hflX	2173018..2174385 (+)	1368	WP_080550867.1	ribosome rescue GTPase HflX	-
D1105_RS10235 (D1105_10310)	-	2174421..2174981 (-)	561	WP_005616339.1	TIGR00730 family Rossman fold protein	-
D1105_RS10240 (D1105_10315)	-	2175044..2175367 (+)	324	WP_005602867.1	MazG nucleotide pyrophosphohydrolase domain-containing protein	-
D1105_RS10245 (D1105_10320)	crp	2175416..2176090 (-)	675	WP_005599747.1	cAMP-activated global transcriptional regulator CRP	Regulator
D1105_RS10250 (D1105_10325)	-	2176168..2176386 (-)	219	WP_005599748.1	YheU family protein	-
D1105_RS10255 (D1105_10330)	slmA	2176392..2177000 (-)	609	WP_005620316.1	nucleoid occlusion factor SlmA	-
D1105_RS10260 (D1105_10335)	dut	2177106..2177561 (-)	456	WP_005599752.1	dUTP diphosphatase	-
D1105_RS10265 (D1105_10340)	coaBC	2177570..2178775 (-)	1206	WP_005616341.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
D1105_RS10270 (D1105_10345)	radC	2178983..2179645 (+)	663	WP_005599756.1	RadC family protein	Machinery gene
D1105_RS10275 (D1105_10350)	rpmB	2179814..2180050 (+)	237	WP_005599762.1	50S ribosomal protein L28	-
D1105_RS10280 (D1105_10355)	rpmG	2180062..2180232 (+)	171	WP_005599764.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25147.02 Da
• Isoelectric Point: 6.5834

>NTDB_id=272092 D1105_RS10245 WP_005599747.1 2175416..2176090(-) (crp) [Actinobacillus pleuropneumoniae strain 8329]
MQDISISTPQLDSELSAPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEDAESLFYIVSGSVAVFIKDEEGKEMILSHLGQ
GEFVGEISLFEDTIQPRTAWVKTKGACEIAEISYKKFKQLVHLNPDILMYLSAQMARRLRQTSRQVSNLAFLDVTGRIAQ
TLMNLAKMPDAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide

• Length: 675 bp

>NTDB_id=272092 D1105_RS10245 WP_005599747.1 2175416..2176090(-) (crp) [Actinobacillus pleuropneumoniae strain 8329]
ATGCAAGATATTTCAATTTCAACACCTCAGCTAGACAGTGAGCTGTCCGCCCCGTCTATTCATGATCCGGCGGTGGAATG
GTTTCTGACTCACTGTCATATTCATCGTTATCCGTCAAAATATACGCTTATTCATGCGGGTGAGGATGCCGAATCATTAT
TCTATATCGTCAGCGGCTCCGTTGCAGTGTTTATTAAAGATGAAGAAGGGAAAGAAATGATCCTTTCTCACCTCGGTCAA
GGTGAATTTGTCGGTGAAATCAGTTTATTTGAAGACACTATTCAACCGCGTACCGCTTGGGTCAAAACCAAAGGCGCTTG
CGAAATTGCGGAAATCTCGTATAAAAAATTCAAACAGCTTGTGCATTTAAATCCGGATATTTTAATGTATCTTTCCGCAC
AAATGGCTCGCCGCCTACGCCAAACCTCACGCCAAGTAAGTAACCTCGCTTTCTTAGACGTAACCGGTCGTATCGCACAA
ACCTTAATGAATCTGGCAAAAATGCCGGATGCAATGACCCACCCTGAAGGAATGCAAATTAAGATTACCCGCCAAGAAAT
CGGTCAAATGGTCGGTTGTTCTCGAGAAACGGTCGGTAGAATCTTAAAAATGCTAGAAGATGAAGGCTTAATTTCAGCAC
ACGGTAAAACCATTGTCGTTTATGGCACTCGCTAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

• Cyclic nucleotide-binding domain (cNMP_binding) (36-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	77.34	90.625	0.701
crp	Haemophilus influenzae Rd KW20	73.892	90.625	0.67
crp	Acinetobacter baumannii D1279779	45.794	95.536	0.437