Detailed information NTG0271446

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: C4N11_RS09360
• Genome accession: NZ_CP026670
• Coordinates: 1774655..1775314 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565006.1
• Uniprot ID: A0A9P1LPI9
• Organism: Streptococcus pneumoniae strain endophthalmitis isolate 335
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1769655..1780314

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C4N11_RS09335 (C4N11_09335)	-	1769951..1770268 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
C4N11_RS09340 (C4N11_09340)	-	1770283..1771179 (-)	897	WP_000825665.1	PEP phosphonomutase	-
C4N11_RS09345 (C4N11_09345)	-	1771182..1772444 (-)	1263	WP_000413347.1	PTS sugar transporter subunit IIC	-
C4N11_RS09350 (C4N11_09350)	-	1772724..1773902 (+)	1179	WP_000175876.1	ROK family transcriptional regulator	-
C4N11_RS09355 (C4N11_09355)	-	1774178..1774585 (-)	408	WP_000155434.1	N-acetyltransferase	-
C4N11_RS09360 (C4N11_09360)	cclA/cilC	1774655..1775314 (+)	660	WP_000565006.1	A24 family peptidase	Machinery gene
C4N11_RS09365 (C4N11_09365)	-	1775366..1776517 (-)	1152	WP_000481756.1	XRE family transcriptional regulator	-
C4N11_RS09370 (C4N11_09370)	-	1776532..1777263 (-)	732	WP_000934017.1	hypothetical protein	-
C4N11_RS09375 (C4N11_09375)	-	1777492..1777593 (+)	102	Protein_1777	prepilin peptidase	-
C4N11_RS09380 (C4N11_09380)	trpA	1777565..1778341 (-)	777	WP_001126993.1	tryptophan synthase subunit alpha	-
C4N11_RS09385 (C4N11_09385)	trpB	1778334..1779557 (-)	1224	WP_000331298.1	tryptophan synthase subunit beta	-
C4N11_RS09390 (C4N11_09390)	-	1779535..1780134 (-)	600	WP_000169888.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24860.02 Da
• Isoelectric Point: 7.5762

>NTDB_id=271446 C4N11_RS09360 WP_000565006.1 1774655..1775314(+) (cclA/cilC) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSQVILITAALTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=271446 C4N11_RS09360 WP_000565006.1 1774655..1775314(+) (cclA/cilC) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGCTTTGACCTTGGGTAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTTCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae Rx1	99.543	100	0.995
cclA/cilC	Streptococcus pneumoniae D39	99.543	100	0.995
cclA/cilC	Streptococcus pneumoniae R6	99.543	100	0.995
cclA/cilC	Streptococcus pneumoniae TIGR4	94.521	100	0.945
cclA/cilC	Streptococcus mitis SK321	92.237	100	0.922
cclA/cilC	Streptococcus mitis NCTC 12261	87.215	100	0.872