Detailed information NTG0271429

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: C4N11_RS04680
• Genome accession: NZ_CP026670
• Coordinates: 875397..876350 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain endophthalmitis isolate 335
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 870397..881350

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C4N11_RS04655 (C4N11_04655)	rpmG	871140..871289 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
C4N11_RS04660 (C4N11_04660)	secG	871329..871562 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
C4N11_RS04665 (C4N11_04665)	rnr	871664..874018 (+)	2355	WP_000654898.1	ribonuclease R	-
C4N11_RS04670 (C4N11_04670)	smpB	873981..874448 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
C4N11_RS04675 (C4N11_04675)	tehB	874464..875324 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
C4N11_RS04680 (C4N11_04680)	coiA	875397..876350 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
C4N11_RS04685 (C4N11_04685)	pepF	876369..878171 (+)	1803	WP_000244125.1	oligoendopeptidase F	Regulator
C4N11_RS04690 (C4N11_04690)	-	878173..878886 (+)	714	WP_000230399.1	O-methyltransferase	-
C4N11_RS04695 (C4N11_04695)	prsA	878953..879894 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
C4N11_RS04700 (C4N11_04700)	-	880011..880352 (-)	342	Protein_882	transposase	-
C4N11_RS04710 (C4N11_04710)	-	880766..880861 (+)	96	Protein_883	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=271429 C4N11_RS04680 WP_000495909.1 875397..876350(+) (coiA) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=271429 C4N11_RS04680 WP_000495909.1 875397..876350(+) (coiA) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435