Detailed information NTG0270147

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: C3438_RS06700
• Genome accession: NZ_CP026533
• Coordinates: 1288681..1289844 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain DKU_NT_04
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1283681..1294844

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C3438_RS06670 (C3438_06670)	-	1283946..1284365 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
C3438_RS06675 (C3438_06675)	comFC	1284439..1285128 (-)	690	WP_201741798.1	phosphoribosyltransferase family protein	Machinery gene
C3438_RS06680 (C3438_06680)	-	1285134..1285418 (-)	285	WP_003151389.1	competence protein ComFB	-
C3438_RS06685 (C3438_06685)	comFA	1285476..1286861 (-)	1386	WP_104842867.1	DEAD/DEAH box helicase	Machinery gene
C3438_RS06690 (C3438_06690)	-	1286969..1287817 (-)	849	WP_003151387.1	DegV family protein	-
C3438_RS06695 (C3438_06695)	degU	1287915..1288604 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
C3438_RS06700 (C3438_06700)	degS	1288681..1289844 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
C3438_RS06705 (C3438_06705)	-	1290067..1290714 (+)	648	WP_007614107.1	YigZ family protein	-
C3438_RS06710 (C3438_06710)	-	1290719..1291912 (+)	1194	WP_104842868.1	LCP family protein	-
C3438_RS06715 (C3438_06715)	-	1292012..1293088 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
C3438_RS06720 (C3438_06720)	-	1293220..1294416 (-)	1197	WP_071182023.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=270147 C3438_RS06700 WP_007407484.1 1288681..1289844(-) (degS) [Bacillus velezensis strain DKU_NT_04]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=270147 C3438_RS06700 WP_007407484.1 1288681..1289844(-) (degS) [Bacillus velezensis strain DKU_NT_04]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGAAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCAGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGCCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGATAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951