Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   C2E56_RS08685 Genome accession   NZ_CP026084
Coordinates   1690801..1691490 (-) Length   229 a.a.
NCBI ID   WP_000516681.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NJ1606     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1685801..1696490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2E56_RS08665 (C2E56_08975) dnaI 1686604..1687506 (-) 903 WP_000843624.1 primosomal protein DnaI -
  C2E56_RS08670 (C2E56_08980) - 1687503..1688678 (-) 1176 WP_017648255.1 DnaD domain protein -
  C2E56_RS08675 (C2E56_08985) nrdR 1688678..1689157 (-) 480 WP_001203682.1 transcriptional regulator NrdR -
  C2E56_RS08680 (C2E56_08990) - 1689306..1690811 (-) 1506 WP_000791116.1 HAMP domain-containing sensor histidine kinase -
  C2E56_RS08685 (C2E56_08995) covR 1690801..1691490 (-) 690 WP_000516681.1 response regulator transcription factor Regulator
  C2E56_RS08690 (C2E56_09000) - 1691725..1692258 (-) 534 WP_000927540.1 YceD family protein -
  C2E56_RS08695 (C2E56_09005) htpX 1692363..1693253 (-) 891 WP_000966821.1 zinc metalloprotease HtpX -
  C2E56_RS08700 (C2E56_09010) - 1693274..1693828 (-) 555 WP_000537056.1 LemA family protein -
  C2E56_RS08705 (C2E56_09015) rsmG 1693956..1694669 (+) 714 WP_000188792.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  C2E56_RS08710 (C2E56_09020) - 1694684..1696063 (+) 1380 WP_000680112.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26547.55 Da        Isoelectric Point: 4.8094

>NTDB_id=266965 C2E56_RS08685 WP_000516681.1 1690801..1691490(-) (covR) [Streptococcus agalactiae strain NJ1606]
MGKKILIIEDEKNLARFVSLELLHEGYDVVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAEKTTYIMMMT
ARDSVMDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQEIETKTKEKGDSGSFRDLSLNTHNRSAMRGDEEISLTKRE
FDLLNVLMTNMNRVMTREELLEHVWKYDVAAETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=266965 C2E56_RS08685 WP_000516681.1 1690801..1691490(-) (covR) [Streptococcus agalactiae strain NJ1606]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTTTACTGGATT
TAATGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTGAAAAAACAACCTATATCATGATGATGACA
GCACGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGAGCAGATGATTATATTGTTAAGCCGTTTGCAATCGA
AGAATTATTAGCACGTGTTAGGGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGAAAAAGGTGATAGCGGTA
GTTTCCGTGATTTATCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAA
TTTGATTTGTTGAATGTCTTGATGACAAATATGAATCGTGTTATGACACGAGAAGAGTTGCTAGAACATGTTTGGAAATA
CGATGTGGCAGCAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAAT
CATATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

79.476

100

0.795
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.228

99.563

0.659
  vicR Streptococcus mutans UA159

45.887

100

0.463
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.437

Multiple sequence alignment