Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   C2E56_RS04990 Genome accession   NZ_CP026084
Coordinates   961955..963268 (-) Length   437 a.a.
NCBI ID   WP_000042576.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NJ1606     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 956955..968268
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2E56_RS04970 (C2E56_05110) - 958435..959208 (-) 774 WP_000622403.1 DUF3307 domain-containing protein -
  C2E56_RS04975 (C2E56_05115) - 959198..959884 (-) 687 WP_000280308.1 SatD family protein -
  C2E56_RS04980 (C2E56_05120) ffh 959951..961516 (-) 1566 WP_000863591.1 signal recognition particle protein -
  C2E56_RS04985 (C2E56_05125) - 961534..961866 (-) 333 WP_000402075.1 putative DNA-binding protein -
  C2E56_RS04990 (C2E56_05130) ciaH 961955..963268 (-) 1314 WP_000042576.1 sensor histidine kinase Regulator
  C2E56_RS04995 (C2E56_05135) ciaR 963252..963932 (-) 681 WP_000590620.1 response regulator transcription factor Regulator
  C2E56_RS05000 (C2E56_05140) - 964094..966643 (-) 2550 WP_000859375.1 M1 family metallopeptidase -
  C2E56_RS05005 (C2E56_05145) phoU 966789..967442 (-) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  C2E56_RS05010 (C2E56_05150) pstB 967476..968234 (-) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 49678.12 Da        Isoelectric Point: 9.4961

>NTDB_id=266956 C2E56_RS04990 WP_000042576.1 961955..963268(-) (ciaH) [Streptococcus agalactiae strain NJ1606]
MSKPIKISKFKKNVSDSHFIHFFTVFSGIFLVMTVIILQVMRYGVYSSVDSSLKYISTHPKNYINMVMSRTAAYLDNSNI
ASVKLKPGGQTVANTDIILFTSEEEVINYFDAFSNYQFLKPNKKNLGGISELTLTNIFGQDETYHAVTVKVNNPAYPNVT
YMTAIVNIDQLVNAKERYEKIIIFVMTTFWIISIGASIYLAKWAQKPIIENYERQKAFVENASHELRTPLAVLQNRLETL
FRKPNATILENSENIASSLDEVRNMRILTTNLLNLARRDDGIKPELAVIKPTLFDSIFENYDLIAQENGKNFTGHNMIQD
SFKTDKTLLKQLMTILFDNAIKYTDNDGSIDFTISETDKYLFLEIADNGPGISEEDKVRIFDRFYRVDKARTRQQGGFGL
GLSLAQQIVNSLRGNITVIDNKPRGSIFKIKLPKVKG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=266956 C2E56_RS04990 WP_000042576.1 961955..963268(-) (ciaH) [Streptococcus agalactiae strain NJ1606]
ATGTCGAAACCGATTAAGATAAGTAAATTCAAAAAAAATGTCTCAGATAGTCATTTTATCCATTTTTTCACAGTTTTTAG
TGGTATTTTTCTGGTTATGACTGTTATCATCCTCCAAGTCATGCGCTATGGTGTTTATTCTTCTGTTGATAGTAGTTTAA
AGTATATCAGTACCCATCCTAAAAATTACATCAATATGGTTATGTCACGTACCGCTGCCTACCTAGATAACTCCAATATC
GCAAGTGTCAAGTTAAAACCCGGCGGTCAGACAGTAGCTAATACTGATATTATTCTTTTTACATCAGAAGAAGAAGTCAT
TAACTATTTTGACGCATTTTCAAACTATCAGTTTTTAAAACCTAATAAAAAAAATCTAGGTGGCATTAGTGAATTAACTT
TAACCAACATCTTTGGTCAAGATGAGACATATCATGCTGTCACCGTAAAAGTTAATAACCCTGCTTATCCTAATGTGACT
TACATGACAGCTATTGTTAATATTGATCAATTAGTAAATGCTAAAGAACGCTATGAAAAAATTATTATATTTGTCATGAC
TACTTTTTGGATTATTTCAATTGGAGCAAGTATCTACTTAGCTAAATGGGCACAAAAACCGATTATAGAAAACTACGAAA
GACAGAAGGCTTTTGTCGAAAATGCTAGCCACGAGCTGCGTACTCCTCTAGCTGTCTTACAAAATCGCCTAGAAACGCTA
TTCAGAAAACCGAATGCCACCATTTTAGAAAATAGTGAAAATATCGCTTCAAGTCTAGATGAAGTACGAAATATGCGTAT
TTTAACCACTAATCTTTTAAACTTAGCAAGACGTGATGATGGAATCAAACCAGAATTAGCTGTTATTAAGCCTACACTTT
TTGATAGTATCTTTGAGAATTATGATCTAATCGCCCAAGAGAATGGTAAAAATTTTACTGGACATAATATGATCCAAGAT
AGTTTCAAAACAGATAAGACACTGCTAAAACAACTCATGACTATTTTATTTGATAATGCTATAAAATATACTGACAATGA
TGGTAGCATTGACTTTACCATATCTGAAACTGATAAGTATCTCTTTTTAGAAATCGCTGATAATGGACCAGGAATTTCAG
AGGAGGATAAAGTCAGAATTTTTGATCGTTTTTATCGTGTTGACAAAGCAAGAACACGACAACAAGGAGGGTTTGGCCTC
GGCCTTTCTTTAGCTCAACAAATCGTTAACTCACTGCGAGGTAATATTACAGTAATTGATAATAAACCTAGAGGCAGTAT
TTTTAAGATAAAACTACCAAAAGTAAAAGGTTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(216-281)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.373

98.169

0.593
  ciaH Streptococcus pneumoniae Rx1

52.143

96.11

0.501
  ciaH Streptococcus pneumoniae D39

52.143

96.11

0.501
  ciaH Streptococcus pneumoniae R6

52.143

96.11

0.501
  ciaH Streptococcus pneumoniae TIGR4

52.143

96.11

0.501

Multiple sequence alignment