Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   C2E46_RS08625 Genome accession   NZ_CP026082
Coordinates   1715219..1715908 (-) Length   229 a.a.
NCBI ID   WP_161501927.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain YZ1605     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1710219..1720908
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2E46_RS08605 (C2E46_08910) dnaI 1711022..1711924 (-) 903 WP_000843626.1 primosomal protein DnaI -
  C2E46_RS08610 (C2E46_08915) - 1711921..1713096 (-) 1176 WP_000074512.1 DnaD domain protein -
  C2E46_RS08615 (C2E46_08920) nrdR 1713096..1713575 (-) 480 WP_001203682.1 transcriptional regulator NrdR -
  C2E46_RS08620 (C2E46_08925) - 1713724..1715229 (-) 1506 WP_000791105.1 HAMP domain-containing histidine kinase -
  C2E46_RS08625 (C2E46_08930) covR 1715219..1715908 (-) 690 WP_161501927.1 response regulator transcription factor Regulator
  C2E46_RS08630 (C2E46_08935) - 1716143..1716676 (-) 534 WP_000927544.1 DUF177 domain-containing protein -
  C2E46_RS08635 (C2E46_08940) htpX 1716781..1717671 (-) 891 WP_000966818.1 zinc metalloprotease HtpX -
  C2E46_RS08640 (C2E46_08945) - 1717692..1718246 (-) 555 WP_000537054.1 LemA family protein -
  C2E46_RS08645 (C2E46_08950) rsmG 1718374..1719087 (+) 714 WP_000188798.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  C2E46_RS08650 (C2E46_08955) - 1719102..1720481 (+) 1380 WP_000680110.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26575.61 Da        Isoelectric Point: 4.8094

>NTDB_id=266912 C2E46_RS08625 WP_161501927.1 1715219..1715908(-) (covR) [Streptococcus agalactiae strain YZ1605]
MGKKILIIEDEKNLARFVSLELLHEGYDVVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAEKTTYIMMMT
ARDSVMDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQEIETKTKEKGDSGSFRDLSLNTHNRSAMRGDEEISLTKRE
FDLLNVLMTNMNRVMTREELLEHVWKYDVAVETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=266912 C2E46_RS08625 WP_161501927.1 1715219..1715908(-) (covR) [Streptococcus agalactiae strain YZ1605]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTCTACTGGATT
TAATGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTGAAAAAACAACCTATATCATGATGATGACA
GCACGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGAGCAGATGATTATATTGTTAAGCCGTTTGCAATCGA
AGAATTATTAGCACGTGTTAGAGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGAAAAAGGTGATAGCGGTA
GTTTCCGTGATTTATCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAA
TTTGATTTATTGAATGTCTTGATGACAAATATGAATCGTGTTATGACACGAGAAGAGTTGTTAGAACATGTTTGGAAATA
CGATGTGGCAGTAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAAT
CATATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

79.476

100

0.795
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.228

99.563

0.659
  vicR Streptococcus mutans UA159

45.887

100

0.463
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.437

Multiple sequence alignment