Detailed information NTG0266754

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RK65_RS03420
• Genome accession: NZ_CP026077
• Coordinates: 635923..636810 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FDAARGOS_7
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 630923..641810

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK65_RS03385 (RK65_003385)	-	630942..631034 (+)	93	WP_010956583.1	hypothetical protein	-
RK65_RS03390 (RK65_003390)	-	631142..631639 (-)	498	WP_001065268.1	glutathione peroxidase	-
RK65_RS03395 (RK65_003395)	-	631649..631909 (-)	261	WP_001789910.1	hypothetical protein	-
RK65_RS03405 (RK65_003405)	-	632291..632404 (-)	114	WP_011447078.1	hypothetical protein	-
RK65_RS03410 (RK65_003410)	-	633063..635063 (-)	2001	WP_000776751.1	ABC transporter permease	-
RK65_RS03415 (RK65_003415)	-	635060..635815 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RK65_RS03420 (RK65_003420)	braS	635923..636810 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RK65_RS03425 (RK65_003425)	braR	636821..637486 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RK65_RS03430 (RK65_003430)	-	637512..637712 (-)	201	WP_000604728.1	hypothetical protein	-
RK65_RS03435 (RK65_003435)	-	637910..639334 (+)	1425	WP_000953744.1	alkaline phosphatase	-
RK65_RS14280 (RK65_003440)	-	639394..639495 (-)	102	WP_000731972.1	SE2200 family small protein	-
RK65_RS03445 (RK65_003445)	-	639617..640072 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RK65_RS03450 (RK65_003450)	-	640317..641078 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=266754 RK65_RS03420 WP_000143419.1 635923..636810(-) (braS) [Staphylococcus aureus strain FDAARGOS_7]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=266754 RK65_RS03420 WP_000143419.1 635923..636810(-) (braS) [Staphylococcus aureus strain FDAARGOS_7]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997