Detailed information NTG0266685

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RL05_RS02790
• Genome accession: NZ_CP026074
• Coordinates: 474518..475561 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDAARGOS_47
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 469518..480561

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RL05_RS02760 (RL05_002760)	-	469939..471195 (-)	1257	WP_001795108.1	aminopeptidase	-
RL05_RS02765 (RL05_002765)	-	471198..471398 (-)	201	WP_000180460.1	DUF1128 family protein	-
RL05_RS02770 (RL05_002770)	-	471545..472009 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RL05_RS02775 (RL05_002775)	-	472016..472291 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
RL05_RS02780 (RL05_002780)	-	472569..473786 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
RL05_RS02785 (RL05_002785)	vraR	473899..474528 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
RL05_RS02790 (RL05_002790)	vraS	474518..475561 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RL05_RS02795 (RL05_002795)	liaF	475558..476259 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RL05_RS02800 (RL05_002800)	-	476274..476660 (-)	387	WP_001110179.1	hypothetical protein	-
RL05_RS02805 (RL05_002805)	map	476877..477635 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RL05_RS02815 (RL05_002815)	-	478166..479152 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
RL05_RS02825 (RL05_002825)	-	479583..479996 (-)	414	WP_001557448.1	hypothetical protein	-
RL05_RS02830 (RL05_002830)	-	480025..480135 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=266685 RL05_RS02790 WP_001017131.1 474518..475561(-) (vraS) [Staphylococcus aureus strain FDAARGOS_47]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=266685 RL05_RS02790 WP_001017131.1 474518..475561(-) (vraS) [Staphylococcus aureus strain FDAARGOS_47]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1