Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   STER_RS01725 Genome accession   NC_008532
Coordinates   310055..310744 (+) Length   229 a.a.
NCBI ID   WP_011680737.1    Uniprot ID   -
Organism   Streptococcus thermophilus LMD-9     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 305055..315744
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STER_RS11590 - 306021..306191 (+) 171 Protein_277 ascorbate 6-phosphate lactonase -
  STER_RS01705 (STER_0350) - 306208..306879 (-) 672 WP_002946492.1 potassium channel family protein -
  STER_RS01710 (STER_0351) - 306919..308283 (-) 1365 WP_011680735.1 TrkH family potassium uptake protein -
  STER_RS01715 (STER_0352) rsmG 308353..309066 (-) 714 WP_011680736.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  STER_RS01720 (STER_0353) - 309363..309899 (+) 537 WP_002946488.1 DUF177 domain-containing protein -
  STER_RS01725 (STER_0354) covR 310055..310744 (+) 690 WP_011680737.1 response regulator transcription factor Regulator
  STER_RS01730 (STER_0355) - 310741..312259 (+) 1519 Protein_283 HAMP domain-containing sensor histidine kinase -
  STER_RS01735 (STER_0356) nrdR 312381..312860 (+) 480 WP_011680738.1 transcriptional regulator NrdR -
  STER_RS01740 (STER_0357) - 312857..314032 (+) 1176 WP_011680739.1 DnaD domain protein -
  STER_RS01745 (STER_0358) dnaI 314036..314938 (+) 903 WP_011680740.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26669.79 Da        Isoelectric Point: 4.7107

>NTDB_id=26650 STER_RS01725 WP_011680737.1 310055..310744(+) (covR) [Streptococcus thermophilus LMD-9]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADEYIIKPFAIEELLARIRATFRRQDIEATKKAPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRER

Nucleotide


Download         Length: 690 bp        

>NTDB_id=26650 STER_RS01725 WP_011680737.1 310055..310744(+) (covR) [Streptococcus thermophilus LMD-9]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGAGTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACTTTCCGTCGTCAAGATATCGAAGCTACTAAGAAGGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGAAAGATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

95.633

100

0.956
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.105

99.563

0.668
  vicR Streptococcus mutans UA159

44.828

100

0.454
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.437

Multiple sequence alignment