Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   RK78_RS11415 Genome accession   NZ_CP026066
Coordinates   2266423..2267109 (-) Length   228 a.a.
NCBI ID   WP_001794049.1    Uniprot ID   A0A0E1X4U4
Organism   Staphylococcus aureus strain FDAARGOS_20     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2261423..2272109
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RK78_RS11395 (RK78_011395) rpsT 2262337..2262588 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  RK78_RS11400 (RK78_011400) holA 2262633..2263607 (-) 975 WP_001282571.1 DNA polymerase III subunit delta -
  RK78_RS11405 (RK78_011405) comEC 2263664..2265865 (-) 2202 WP_000967506.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  RK78_RS11410 (RK78_011410) - 2265870..2266331 (-) 462 WP_000439692.1 ComE operon protein 2 -
  RK78_RS11415 (RK78_011415) comEA 2266423..2267109 (-) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  RK78_RS11420 (RK78_011420) - 2267149..2267865 (-) 717 WP_000084835.1 class I SAM-dependent methyltransferase -
  RK78_RS11425 (RK78_011425) rsfS 2267868..2268221 (-) 354 WP_001088020.1 ribosome silencing factor -
  RK78_RS11430 (RK78_011430) yqeK 2268222..2268806 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  RK78_RS11435 (RK78_011435) nadD 2268796..2269365 (-) 570 WP_000822938.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  RK78_RS11440 (RK78_011440) yhbY 2269368..2269658 (-) 291 WP_000955232.1 ribosome assembly RNA-binding protein YhbY -
  RK78_RS11445 (RK78_011445) aroE 2269662..2270468 (-) 807 WP_000666750.1 shikimate dehydrogenase -
  RK78_RS11450 (RK78_011450) yqeH 2270482..2271582 (-) 1101 WP_001280133.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25766.38 Da        Isoelectric Point: 9.3383

>NTDB_id=266360 RK78_RS11415 WP_001794049.1 2266423..2267109(-) (comEA) [Staphylococcus aureus strain FDAARGOS_20]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=266360 RK78_RS11415 WP_001794049.1 2266423..2267109(-) (comEA) [Staphylococcus aureus strain FDAARGOS_20]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X4U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

95.595

99.561

0.952
  comEA Staphylococcus aureus N315

95.595

99.561

0.952

Multiple sequence alignment