Detailed information
Bioinformatically predicted
Overview
| Name | comGA | Type | Machinery gene |
| Locus tag | C2I17_RS21145 | Genome accession | NZ_CP026040 |
| Coordinates | 4445800..4446591 (+) | Length | 263 a.a. |
| NCBI ID | WP_338137882.1 | Uniprot ID | - |
| Organism | Niallia circulans strain PK3_15 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 4444225..4501169 | 4445800..4446591 | within | 0 |
Gene organization within MGE regions
Location: 4444225..4501169
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C2I17_RS21135 (C2I17_20965) | - | 4444225..4445157 (+) | 933 | WP_249878184.1 | cation diffusion facilitator family transporter | - |
| C2I17_RS21145 (C2I17_20975) | comGA | 4445800..4446591 (+) | 792 | WP_338137882.1 | ATPase, T2SS/T4P/T4SS family | Machinery gene |
| C2I17_RS21150 (C2I17_20980) | - | 4446527..4447981 (-) | 1455 | WP_249878185.1 | recombinase family protein | - |
| C2I17_RS21155 (C2I17_20985) | - | 4448003..4449064 (-) | 1062 | WP_249878186.1 | ImmA/IrrE family metallo-endopeptidase | - |
| C2I17_RS21160 (C2I17_20990) | - | 4449051..4449410 (-) | 360 | WP_249878187.1 | helix-turn-helix domain-containing protein | - |
| C2I17_RS21165 (C2I17_20995) | - | 4449516..4449785 (+) | 270 | WP_249878188.1 | helix-turn-helix transcriptional regulator | - |
| C2I17_RS21170 | - | 4449878..4450042 (+) | 165 | WP_249878189.1 | hypothetical protein | - |
| C2I17_RS21175 (C2I17_21000) | - | 4449999..4450754 (+) | 756 | WP_249878190.1 | phage regulatory protein/antirepressor Ant | - |
| C2I17_RS24880 | - | 4451065..4451190 (+) | 126 | WP_275068781.1 | hypothetical protein | - |
| C2I17_RS21180 (C2I17_21005) | - | 4451183..4451488 (+) | 306 | WP_249878191.1 | hypothetical protein | - |
| C2I17_RS21185 (C2I17_21010) | - | 4451481..4451690 (+) | 210 | WP_249878192.1 | YqaI family protein | - |
| C2I17_RS21190 | - | 4451702..4451854 (+) | 153 | WP_164463660.1 | DUF6906 family protein | - |
| C2I17_RS21195 | - | 4451950..4452123 (+) | 174 | WP_171509798.1 | hypothetical protein | - |
| C2I17_RS21200 (C2I17_21015) | - | 4452123..4453010 (+) | 888 | WP_249878193.1 | hypothetical protein | - |
| C2I17_RS21205 (C2I17_21020) | - | 4452961..4453770 (+) | 810 | WP_249878194.1 | PD-(D/E)XK nuclease-like domain-containing protein | - |
| C2I17_RS21210 (C2I17_21025) | - | 4453954..4454778 (+) | 825 | WP_249879589.1 | replication protein | - |
| C2I17_RS21215 (C2I17_21030) | - | 4454666..4455532 (+) | 867 | WP_420916350.1 | ATP-binding protein | - |
| C2I17_RS21220 | - | 4455525..4455701 (+) | 177 | WP_249878195.1 | hypothetical protein | - |
| C2I17_RS21225 (C2I17_21035) | - | 4455691..4455912 (+) | 222 | WP_249878196.1 | hypothetical protein | - |
| C2I17_RS21230 (C2I17_21040) | - | 4455956..4456165 (+) | 210 | WP_249878197.1 | hypothetical protein | - |
| C2I17_RS21235 (C2I17_21045) | - | 4456162..4456764 (+) | 603 | WP_249878198.1 | hypothetical protein | - |
| C2I17_RS21240 (C2I17_21050) | - | 4456734..4456889 (+) | 156 | WP_249878199.1 | Fur-regulated basic protein FbpA | - |
| C2I17_RS21245 (C2I17_21055) | - | 4456880..4457323 (+) | 444 | WP_249878200.1 | hypothetical protein | - |
| C2I17_RS21250 (C2I17_21065) | - | 4457666..4457968 (+) | 303 | WP_249878201.1 | MazG-like family protein | - |
| C2I17_RS21255 (C2I17_21070) | - | 4458288..4458665 (+) | 378 | WP_249878202.1 | hypothetical protein | - |
| C2I17_RS21260 (C2I17_21075) | - | 4458762..4459220 (+) | 459 | WP_249879591.1 | ArpU family phage packaging/lysis transcriptional regulator | - |
| C2I17_RS21265 (C2I17_21080) | - | 4459247..4459618 (-) | 372 | WP_249878203.1 | GIY-YIG nuclease family protein | - |
| C2I17_RS21270 (C2I17_21085) | - | 4460095..4461045 (+) | 951 | WP_249878204.1 | hypothetical protein | - |
| C2I17_RS21275 (C2I17_21090) | - | 4461020..4461625 (+) | 606 | WP_249878205.1 | hypothetical protein | - |
| C2I17_RS21280 | - | 4461698..4461874 (-) | 177 | WP_249878206.1 | hypothetical protein | - |
| C2I17_RS21285 (C2I17_21095) | - | 4462032..4462676 (+) | 645 | WP_249878207.1 | hypothetical protein | - |
| C2I17_RS21290 (C2I17_21100) | tnpA | 4462861..4463316 (+) | 456 | WP_095330205.1 | IS200/IS605 family transposase | - |
| C2I17_RS21295 (C2I17_21105) | - | 4463701..4463895 (+) | 195 | WP_249878208.1 | hypothetical protein | - |
| C2I17_RS21300 (C2I17_21110) | - | 4463901..4464332 (+) | 432 | WP_249878209.1 | hypothetical protein | - |
| C2I17_RS21305 (C2I17_21115) | - | 4464361..4464693 (+) | 333 | WP_249878210.1 | hypothetical protein | - |
| C2I17_RS21310 (C2I17_21120) | - | 4464693..4465004 (+) | 312 | WP_249878211.1 | HNH endonuclease | - |
| C2I17_RS21315 (C2I17_21125) | - | 4465086..4465478 (+) | 393 | WP_249878212.1 | P27 family phage terminase small subunit | - |
| C2I17_RS21320 (C2I17_21130) | - | 4465475..4467190 (+) | 1716 | WP_249878213.1 | terminase large subunit | - |
| C2I17_RS21325 (C2I17_21135) | - | 4467207..4468379 (+) | 1173 | WP_249878214.1 | phage portal protein | - |
| C2I17_RS21330 (C2I17_21140) | - | 4468380..4468949 (+) | 570 | WP_144545100.1 | HK97 family phage prohead protease | - |
| C2I17_RS21335 (C2I17_21145) | - | 4468942..4470147 (+) | 1206 | WP_249878215.1 | phage major capsid protein | - |
| C2I17_RS21340 | - | 4470170..4470346 (+) | 177 | WP_249878216.1 | hypothetical protein | - |
| C2I17_RS21345 (C2I17_21150) | - | 4470339..4470650 (+) | 312 | WP_249878217.1 | hypothetical protein | - |
| C2I17_RS21350 (C2I17_21155) | - | 4470619..4470984 (+) | 366 | WP_249878218.1 | hypothetical protein | - |
| C2I17_RS21355 (C2I17_21160) | - | 4470977..4471336 (+) | 360 | WP_420916351.1 | HK97 gp10 family phage protein | - |
| C2I17_RS21360 (C2I17_21165) | - | 4471333..4471650 (+) | 318 | WP_249878219.1 | hypothetical protein | - |
| C2I17_RS21365 (C2I17_21170) | - | 4471652..4472290 (+) | 639 | WP_249878220.1 | major tail protein | - |
| C2I17_RS21370 (C2I17_21175) | - | 4472290..4472634 (+) | 345 | WP_249878221.1 | hypothetical protein | - |
| C2I17_RS21375 (C2I17_21185) | - | 4472872..4475694 (+) | 2823 | WP_249878222.1 | phage tail protein | - |
| C2I17_RS21380 (C2I17_21190) | - | 4475684..4476484 (+) | 801 | WP_249878223.1 | distal tail protein Dit | - |
| C2I17_RS21385 (C2I17_21195) | - | 4476496..4478190 (+) | 1695 | WP_249878224.1 | SGNH/GDSL hydrolase family protein | - |
| C2I17_RS21390 (C2I17_21200) | - | 4478248..4480119 (+) | 1872 | WP_249878225.1 | phage tail spike protein | - |
| C2I17_RS21395 (C2I17_21205) | - | 4480119..4480385 (+) | 267 | WP_249878226.1 | hypothetical protein | - |
| C2I17_RS21400 (C2I17_21210) | - | 4480478..4480792 (+) | 315 | WP_249878227.1 | hypothetical protein | - |
| C2I17_RS21405 (C2I17_21215) | - | 4480805..4481098 (+) | 294 | WP_249878228.1 | holin | - |
| C2I17_RS21410 (C2I17_21220) | - | 4481114..4481956 (+) | 843 | WP_249878229.1 | glycoside hydrolase family protein | - |
| C2I17_RS21415 (C2I17_21225) | - | 4482069..4482563 (-) | 495 | WP_249878230.1 | hypothetical protein | - |
| C2I17_RS24885 | - | 4482753..4482875 (+) | 123 | WP_275068782.1 | hypothetical protein | - |
| C2I17_RS21420 (C2I17_21230) | - | 4482863..4483225 (-) | 363 | WP_249878231.1 | hypothetical protein | - |
| C2I17_RS21425 (C2I17_21235) | - | 4483240..4483569 (-) | 330 | WP_249878232.1 | YolD-like family protein | - |
| C2I17_RS21430 (C2I17_21240) | - | 4483747..4483998 (+) | 252 | WP_249878233.1 | hypothetical protein | - |
| C2I17_RS21435 (C2I17_21245) | - | 4484087..4485085 (-) | 999 | WP_249878234.1 | hypothetical protein | - |
| C2I17_RS21440 (C2I17_21250) | - | 4485188..4485508 (-) | 321 | WP_249878235.1 | DUF771 domain-containing protein | - |
| C2I17_RS21445 (C2I17_21255) | - | 4485533..4485742 (-) | 210 | WP_249878236.1 | helix-turn-helix domain-containing protein | - |
| C2I17_RS21450 (C2I17_21260) | - | 4485900..4486295 (+) | 396 | WP_249878237.1 | ATPase, T2SS/T4P/T4SS family | - |
| C2I17_RS21455 (C2I17_21265) | comGB | 4486285..4487319 (+) | 1035 | WP_249878238.1 | competence type IV pilus assembly protein ComGB | - |
| C2I17_RS21460 (C2I17_21270) | comGC | 4487332..4487646 (+) | 315 | WP_095332771.1 | competence type IV pilus major pilin ComGC | - |
| C2I17_RS21465 (C2I17_21275) | comGD | 4487643..4488080 (+) | 438 | WP_249878239.1 | competence type IV pilus minor pilin ComGD | - |
| C2I17_RS21470 (C2I17_21280) | - | 4488064..4488387 (+) | 324 | WP_163185985.1 | hypothetical protein | - |
| C2I17_RS21475 (C2I17_21285) | comGF | 4488384..4488827 (+) | 444 | WP_235973249.1 | competence type IV pilus minor pilin ComGF | - |
| C2I17_RS21480 (C2I17_21290) | comGG | 4488834..4489214 (+) | 381 | WP_249878240.1 | competence type IV pilus minor pilin ComGG | - |
| C2I17_RS21485 (C2I17_21295) | - | 4489269..4489457 (+) | 189 | WP_249878241.1 | YqzE family protein | - |
| C2I17_RS21490 (C2I17_21300) | - | 4489522..4490328 (-) | 807 | WP_095332781.1 | YqhG family protein | - |
| C2I17_RS21495 (C2I17_21305) | - | 4490297..4492009 (-) | 1713 | WP_095332783.1 | DEAD/DEAH box helicase | - |
| C2I17_RS21500 (C2I17_21310) | gcvT | 4492589..4493689 (+) | 1101 | WP_249878242.1 | glycine cleavage system aminomethyltransferase GcvT | - |
| C2I17_RS21505 (C2I17_21315) | gcvPA | 4493747..4495093 (+) | 1347 | WP_163185994.1 | aminomethyl-transferring glycine dehydrogenase subunit GcvPA | - |
| C2I17_RS21510 (C2I17_21320) | gcvPB | 4495086..4496543 (+) | 1458 | WP_095332789.1 | aminomethyl-transferring glycine dehydrogenase subunit GcvPB | - |
| C2I17_RS21515 (C2I17_21325) | - | 4496640..4497017 (-) | 378 | WP_371000273.1 | rhodanese-like domain-containing protein | - |
| C2I17_RS21520 (C2I17_21330) | - | 4497226..4498062 (+) | 837 | WP_095332791.1 | lipoate--protein ligase family protein | - |
| C2I17_RS21525 (C2I17_21340) | - | 4498617..4501169 (+) | 2553 | WP_249878243.1 | vitamin B12-dependent ribonucleotide reductase | - |
Sequence
Protein
Download Length: 263 a.a. Molecular weight: 29604.39 Da Isoelectric Point: 9.0233
>NTDB_id=265947 C2I17_RS21145 WP_338137882.1 4445800..4446591(+) (comGA) [Niallia circulans strain PK3_15]
MLSIEALANRIICEAVEQNATDIHITPKQKESVLQFRIANHLINHLVISANECDKLISHFKFTASMDIGERRKPQNGSIS
TTVKGQYIGLRLSTLPSHPHESLVIRILSDQNMLPIYHISLFPNISRKLISLLKHAHGLIILTGPTGSGKTTTLYSLLNE
NAHLYQRNVISLEDPIEKTQENVLQIQVNEKAGITYSTGLKAILRHDPDIIMVGEIRDKETAHIAIRASLTGHLVLIIDT
CRVIRRLYFQLQQTQVLVVAQFY
MLSIEALANRIICEAVEQNATDIHITPKQKESVLQFRIANHLINHLVISANECDKLISHFKFTASMDIGERRKPQNGSIS
TTVKGQYIGLRLSTLPSHPHESLVIRILSDQNMLPIYHISLFPNISRKLISLLKHAHGLIILTGPTGSGKTTTLYSLLNE
NAHLYQRNVISLEDPIEKTQENVLQIQVNEKAGITYSTGLKAILRHDPDIIMVGEIRDKETAHIAIRASLTGHLVLIIDT
CRVIRRLYFQLQQTQVLVVAQFY
Nucleotide
Download Length: 792 bp
>NTDB_id=265947 C2I17_RS21145 WP_338137882.1 4445800..4446591(+) (comGA) [Niallia circulans strain PK3_15]
GTGTTATCAATTGAAGCTCTAGCAAATCGTATTATTTGTGAGGCAGTAGAACAGAATGCTACTGATATTCACATAACCCC
AAAACAAAAGGAATCTGTCCTCCAATTCCGAATTGCCAATCATTTAATTAATCACTTAGTAATTTCAGCAAATGAATGCG
ACAAGTTGATCTCTCATTTCAAATTTACAGCATCTATGGATATTGGCGAAAGAAGAAAACCGCAAAATGGATCTATTTCC
ACAACAGTCAAAGGTCAGTATATTGGCTTACGACTTTCAACCTTACCATCTCACCCTCATGAGAGTTTAGTAATTCGTAT
ACTTTCCGACCAAAATATGCTTCCAATCTATCACATCTCTTTATTTCCGAATATTTCTCGTAAATTAATCTCCTTGTTAA
AGCATGCACACGGATTAATAATTCTGACCGGTCCAACTGGGTCTGGCAAGACAACAACACTCTACTCTCTCCTAAATGAA
AATGCACATCTTTATCAGCGAAATGTGATTAGCTTAGAAGATCCCATTGAAAAAACGCAGGAAAACGTTTTGCAAATTCA
AGTCAATGAGAAAGCTGGTATTACGTATTCCACTGGCTTAAAAGCAATTCTTCGCCATGATCCAGATATTATTATGGTTG
GAGAAATCCGCGACAAAGAAACTGCTCATATTGCGATAAGGGCGAGCTTAACAGGTCATTTAGTATTGATAATAGACACA
TGCAGGGTTATAAGAAGGCTATACTTTCAATTACAACAGACTCAGGTGTTAGTCGTTGCTCAGTTTTATTAA
GTGTTATCAATTGAAGCTCTAGCAAATCGTATTATTTGTGAGGCAGTAGAACAGAATGCTACTGATATTCACATAACCCC
AAAACAAAAGGAATCTGTCCTCCAATTCCGAATTGCCAATCATTTAATTAATCACTTAGTAATTTCAGCAAATGAATGCG
ACAAGTTGATCTCTCATTTCAAATTTACAGCATCTATGGATATTGGCGAAAGAAGAAAACCGCAAAATGGATCTATTTCC
ACAACAGTCAAAGGTCAGTATATTGGCTTACGACTTTCAACCTTACCATCTCACCCTCATGAGAGTTTAGTAATTCGTAT
ACTTTCCGACCAAAATATGCTTCCAATCTATCACATCTCTTTATTTCCGAATATTTCTCGTAAATTAATCTCCTTGTTAA
AGCATGCACACGGATTAATAATTCTGACCGGTCCAACTGGGTCTGGCAAGACAACAACACTCTACTCTCTCCTAAATGAA
AATGCACATCTTTATCAGCGAAATGTGATTAGCTTAGAAGATCCCATTGAAAAAACGCAGGAAAACGTTTTGCAAATTCA
AGTCAATGAGAAAGCTGGTATTACGTATTCCACTGGCTTAAAAGCAATTCTTCGCCATGATCCAGATATTATTATGGTTG
GAGAAATCCGCGACAAAGAAACTGCTCATATTGCGATAAGGGCGAGCTTAACAGGTCATTTAGTATTGATAATAGACACA
TGCAGGGTTATAAGAAGGCTATACTTTCAATTACAACAGACTCAGGTGTTAGTCGTTGCTCAGTTTTATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGA | Bacillus subtilis subsp. subtilis str. 168 |
51.292 |
100 |
0.529 |
| pilB | Glaesserella parasuis strain SC1401 |
39.147 |
98.099 |
0.384 |
| comYA | Streptococcus mutans UA140 |
42.373 |
89.734 |
0.38 |
| comYA | Streptococcus mutans UA159 |
42.373 |
89.734 |
0.38 |
| pilB | Haemophilus influenzae Rd KW20 |
36.33 |
100 |
0.369 |
| comGA | Staphylococcus aureus MW2 |
40.254 |
89.734 |
0.361 |
| comGA | Staphylococcus aureus N315 |
40.254 |
89.734 |
0.361 |