Detailed information NTG0026407

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: APL_RS10410
• Genome accession: NC_009053
• Coordinates: 2194502..2195176 (-)
• Length: 224 a.a.
• NCBI ID: WP_005599747.1
• Uniprot ID: -
• Organism: Actinobacillus pleuropneumoniae serovar 5b str. L20
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2189502..2200176

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
APL_RS10380 (APL_1959)	adhP	2189591..2190640 (+)	1050	WP_005602862.1	alcohol dehydrogenase AdhP	-
APL_RS10385 (APL_1960)	miaA	2190772..2191716 (+)	945	WP_009874864.1	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	-
APL_RS10390 (APL_1961)	hfq	2191781..2192059 (+)	279	WP_005599741.1	RNA chaperone Hfq	-
APL_RS10395 (APL_1962)	hflX	2192097..2193464 (+)	1368	WP_080512818.1	ribosome rescue GTPase HflX	-
APL_RS10400 (APL_1963)	-	2193500..2194060 (-)	561	WP_005606066.1	TIGR00730 family Rossman fold protein	-
APL_RS10405 (APL_1964)	-	2194123..2194446 (+)	324	WP_005606068.1	MazG nucleotide pyrophosphohydrolase domain-containing protein	-
APL_RS10410 (APL_1965)	crp	2194502..2195176 (-)	675	WP_005599747.1	cAMP-activated global transcriptional regulator CRP	Regulator
APL_RS10415 (APL_1966)	-	2195254..2195472 (-)	219	WP_005599748.1	YheU family protein	-
APL_RS10420 (APL_1967)	slmA	2195478..2196086 (-)	609	WP_005620316.1	nucleoid occlusion factor SlmA	-
APL_RS10425 (APL_1968)	dut	2196192..2196647 (-)	456	WP_005606071.1	dUTP diphosphatase	-
APL_RS10430 (APL_1969)	coaBC	2196656..2197861 (-)	1206	WP_005602882.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
APL_RS10435 (APL_1970)	radC	2198069..2198731 (+)	663	WP_005599756.1	DNA repair protein RadC	Machinery gene
APL_RS10440 (APL_1971)	rpmB	2198900..2199136 (+)	237	WP_005599762.1	50S ribosomal protein L28	-
APL_RS10445 (APL_1972)	rpmG	2199148..2199318 (+)	171	WP_005599764.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25147.02 Da
• Isoelectric Point: 6.5834

>NTDB_id=26407 APL_RS10410 WP_005599747.1 2194502..2195176(-) (crp) [Actinobacillus pleuropneumoniae serovar 5b str. L20]
MQDISISTPQLDSELSAPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEDAESLFYIVSGSVAVFIKDEEGKEMILSHLGQ
GEFVGEISLFEDTIQPRTAWVKTKGACEIAEISYKKFKQLVHLNPDILMYLSAQMARRLRQTSRQVSNLAFLDVTGRIAQ
TLMNLAKMPDAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide

• Length: 675 bp

>NTDB_id=26407 APL_RS10410 WP_005599747.1 2194502..2195176(-) (crp) [Actinobacillus pleuropneumoniae serovar 5b str. L20]
ATGCAAGATATTTCAATTTCAACACCTCAGCTAGACAGTGAGCTGTCCGCCCCGTCTATTCATGATCCGGCGGTGGAATG
GTTTCTGACTCACTGTCATATTCATCGTTATCCGTCAAAATATACGCTTATTCATGCGGGTGAGGATGCCGAATCATTAT
TCTATATCGTCAGCGGCTCCGTTGCAGTGTTTATTAAAGATGAAGAAGGGAAAGAAATGATCCTTTCTCACCTCGGTCAA
GGTGAATTTGTCGGTGAAATCAGTTTATTCGAAGACACTATTCAACCGCGTACCGCTTGGGTCAAAACCAAAGGCGCTTG
CGAAATTGCGGAAATCTCGTATAAAAAATTCAAACAGCTTGTGCATTTAAATCCGGATATTCTTATGTATCTTTCCGCAC
AAATGGCTCGCCGCCTACGCCAAACCTCACGCCAAGTAAGTAACCTCGCTTTCTTAGACGTAACCGGTCGTATCGCACAA
ACCTTAATGAATCTGGCAAAAATGCCGGATGCAATGACCCACCCTGAAGGAATGCAAATTAAGATTACCCGCCAAGAAAT
CGGTCAAATGGTCGGTTGTTCTCGAGAAACGGTCGGTAGAATCTTAAAAATGCTAGAAGATGAAGGCTTAATTTCAGCAC
ACGGTAAAACCATTGTCGTTTATGGCACTCGCTAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

• Cyclic nucleotide-binding domain (cNMP_binding) (36-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	77.34	90.625	0.701
crp	Haemophilus influenzae Rd KW20	73.892	90.625	0.67
crp	Acinetobacter baumannii D1279779	45.794	95.536	0.437