Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   DV447_RS13015 Genome accession   NZ_CP031256
Coordinates   2626533..2627189 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain M16807     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2621533..2632189
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV447_RS12990 dcyD 2622412..2623398 (+) 987 WP_001128236.1 D-cysteine desulfhydrase -
  DV447_RS12995 tcyL 2623413..2624081 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  DV447_RS13000 tcyN 2624078..2624830 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  DV447_RS13005 sdiA 2625060..2625782 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  DV447_RS13010 yecF 2625850..2626074 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  DV447_RS26505 yecU 2626061..2626237 (-) 177 WP_001304283.1 protein YecU -
  DV447_RS13015 letA 2626533..2627189 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  DV447_RS13020 uvrC 2627186..2629018 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  DV447_RS13025 pgsA 2629075..2629623 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  DV447_RS13045 yecA 2630272..2630937 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=263886 DV447_RS13015 WP_000611328.1 2626533..2627189(+) (letA) [Escherichia coli strain M16807]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=263886 DV447_RS13015 WP_000611328.1 2626533..2627189(+) (letA) [Escherichia coli strain M16807]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment