Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   DV129_RS07960 Genome accession   NZ_CP031247
Coordinates   1464599..1464835 (-) Length   78 a.a.
NCBI ID   WP_000939546.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M23734     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 1459599..1469835
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV129_RS07930 - 1459788..1460021 (+) 234 WP_000156422.1 hypothetical protein -
  DV129_RS07935 - 1460021..1460284 (+) 264 WP_000285962.1 type II toxin-antitoxin system RelE/ParE family toxin -
  DV129_RS07940 - 1460297..1460677 (+) 381 Protein_1504 ImmA/IrrE family metallo-endopeptidase -
  DV129_RS07945 - 1460715..1461527 (+) 813 WP_001174227.1 HIRAN domain-containing protein -
  DV129_RS07950 - 1461702..1462850 (+) 1149 WP_000876726.1 site-specific integrase -
  DV129_RS07955 - 1463082..1464368 (-) 1287 WP_000205044.1 adenylosuccinate synthase -
  DV129_RS07960 comW 1464599..1464835 (-) 237 WP_000939546.1 sigma(X)-activator ComW Regulator
  DV129_RS07965 - 1465100..1465897 (+) 798 Protein_1509 transposase -
  DV129_RS07970 - 1465932..1466778 (-) 847 Protein_1510 IS630 family transposase -

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9686.14 Da        Isoelectric Point: 6.7051

>NTDB_id=263273 DV129_RS07960 WP_000939546.1 1464599..1464835(-) (comW) [Streptococcus pneumoniae strain M23734]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=263273 DV129_RS07960 WP_000939546.1 1464599..1464835(-) (comW) [Streptococcus pneumoniae strain M23734]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987

  comW Streptococcus pneumoniae D39

98.718

100

0.987

  comW Streptococcus pneumoniae R6

98.718

100

0.987

  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987

  comW Streptococcus mitis SK321

76.923

100

0.769

  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756