Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   C0099_RS02335 Genome accession   NZ_CP025682
Coordinates   497920..499260 (+) Length   446 a.a.
NCBI ID   WP_102245954.1    Uniprot ID   A0A2I6S3P2
Organism   Pseudazoarcus pumilus strain SY39     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 492920..504260
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C0099_RS02305 (C0099_02305) - 493554..494207 (-) 654 WP_102245948.1 class II aldolase/adducin family protein -
  C0099_RS02310 (C0099_02310) mtnA 494200..495273 (-) 1074 WP_102245949.1 S-methyl-5-thioribose-1-phosphate isomerase -
  C0099_RS02315 (C0099_02315) - 495384..495608 (+) 225 WP_102245950.1 DUF1902 domain-containing protein -
  C0099_RS02325 (C0099_02325) - 496134..496376 (+) 243 WP_102245952.1 PP0621 family protein -
  C0099_RS02330 (C0099_02330) - 496373..497923 (+) 1551 WP_102245953.1 PAS domain-containing sensor histidine kinase -
  C0099_RS02335 (C0099_02335) pilR 497920..499260 (+) 1341 WP_102245954.1 sigma-54 dependent transcriptional regulator Regulator
  C0099_RS02340 (C0099_02340) - 499450..499776 (+) 327 WP_228151631.1 helix-turn-helix transcriptional regulator -
  C0099_RS02345 (C0099_02345) - 499776..501074 (+) 1299 WP_102245956.1 type II toxin-antitoxin system HipA family toxin -
  C0099_RS02350 (C0099_02350) - 501153..502181 (+) 1029 WP_102245957.1 IS30 family transposase -
  C0099_RS16305 (C0099_02355) - 502358..502426 (+) 69 Protein_471 helix-turn-helix domain-containing protein -
  C0099_RS02360 (C0099_02360) - 502517..502747 (+) 231 WP_102245959.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
  C0099_RS02365 (C0099_02365) - 502747..503133 (+) 387 WP_102245960.1 type II toxin-antitoxin system VapC family toxin -
  C0099_RS15815 - 503210..503416 (+) 207 WP_123785209.1 hypothetical protein -
  C0099_RS02370 (C0099_02370) - 503388..503672 (+) 285 WP_102245961.1 nucleotidyltransferase family protein -
  C0099_RS02375 (C0099_02375) - 503682..504044 (+) 363 WP_102245962.1 DUF86 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 48075.94 Da        Isoelectric Point: 6.3467

>NTDB_id=263212 C0099_RS02335 WP_102245954.1 497920..499260(+) (pilR) [Pseudazoarcus pumilus strain SY39]
MNAESGARADVLVIDDEADIRELLELALLRMGLSCDTAGSVAEARERLASGSYRLCLTDMRLPDGDGLDLVAYIQQAHAG
LPVAVISAHGSIDTAIRALKLGAFDFVTKPVEVKAVRALVEHALRVPEHAQDEPEADGVRRLIGRSAAIEHLRAQVARLA
RSQAPVFIHGESGTGKEVIARSIHALGPRAGGAFVPVNCGAIPHELMESEFFGHVRGSFSGATADKPGLFRAAQGGTLFL
DEVAELPLAMQVKLLRAIQERAVRPVGAHAEEAVDVRVLSASHRDLAALVAEGRFRQDLFYRINVIALHVPPLRERPEDI
EALAAHILARLAARDGGPAQRLSAESLAALRAHPFPGNVRELENLLERACALCDSDVITPADLALDAAPAPLASPVTPPP
GQGGDDERSHILRALEETRWNRSEAARRLGMTLRQLRYRLQKWGME

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=263212 C0099_RS02335 WP_102245954.1 497920..499260(+) (pilR) [Pseudazoarcus pumilus strain SY39]
ATGAACGCAGAGTCGGGCGCACGTGCCGACGTGCTGGTCATCGACGACGAGGCCGACATCCGCGAACTGCTGGAACTCGC
GCTGCTGCGCATGGGCCTGAGTTGCGACACCGCCGGCAGCGTGGCCGAGGCGCGCGAGCGGCTGGCGTCGGGGAGCTATC
GCTTGTGCCTGACCGACATGCGCCTGCCCGACGGTGACGGCCTCGACCTGGTGGCCTACATCCAGCAGGCGCACGCCGGC
CTGCCGGTGGCGGTGATCTCGGCCCATGGCAGCATCGACACGGCGATTCGCGCGCTCAAGCTGGGCGCCTTCGATTTCGT
CACCAAGCCGGTCGAGGTCAAGGCCGTGCGCGCGCTCGTCGAGCACGCGCTGCGCGTGCCCGAACACGCCCAGGATGAAC
CCGAGGCGGACGGTGTGCGGCGGCTCATCGGCCGTTCCGCCGCCATCGAGCACCTGCGCGCCCAGGTCGCACGGCTCGCG
CGCAGTCAGGCGCCGGTGTTCATCCATGGCGAATCCGGCACCGGCAAGGAAGTCATCGCGCGCTCCATCCACGCGCTCGG
CCCGCGCGCCGGCGGTGCCTTCGTGCCGGTCAACTGCGGCGCGATCCCGCATGAGCTGATGGAGAGCGAATTCTTCGGCC
ACGTGCGCGGCAGCTTTTCCGGCGCCACCGCCGACAAGCCCGGCCTGTTCCGCGCCGCGCAGGGCGGCACACTGTTCCTC
GACGAGGTTGCCGAGTTGCCGTTGGCCATGCAAGTCAAGCTGCTGCGCGCCATCCAGGAGCGCGCCGTGCGCCCGGTCGG
GGCGCACGCCGAAGAAGCCGTGGACGTGCGCGTGCTGTCCGCCTCGCACCGCGATCTGGCCGCATTGGTGGCTGAAGGGC
GCTTCCGCCAGGACTTGTTCTACCGCATCAACGTCATCGCGCTGCACGTGCCGCCGCTGCGCGAGCGTCCCGAGGACATC
GAGGCGCTGGCTGCGCACATCCTCGCGCGGCTCGCCGCGCGCGACGGCGGGCCTGCGCAACGCTTGTCGGCCGAGTCGCT
CGCTGCGCTGCGCGCCCATCCATTCCCCGGCAACGTGCGCGAGCTCGAGAACCTGCTCGAACGCGCCTGCGCACTGTGCG
ATTCCGATGTGATCACGCCCGCCGACCTCGCGCTGGACGCCGCGCCAGCGCCCCTCGCCTCGCCCGTGACGCCGCCGCCC
GGTCAGGGCGGCGACGACGAGCGCAGCCACATCCTGCGCGCGCTGGAAGAAACCCGCTGGAACCGCAGCGAGGCCGCCCG
CCGCCTGGGCATGACGCTGCGCCAGTTGCGCTACCGGCTGCAGAAGTGGGGCATGGAATAG

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(142-308)

Bacterial regulatory protein, Fis family (HTH_8)

(407-443)

Response regulator receiver domain (Response_reg)

(11-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I6S3P2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

60.314

100

0.603
  pilR Acinetobacter baumannii strain A118

47.516

100

0.493
  luxO Vibrio cholerae strain A1552

36.444

100

0.368

Multiple sequence alignment