Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   DV131_RS02240 Genome accession   NZ_CP031246
Coordinates   387661..388143 (-) Length   160 a.a.
NCBI ID   WP_240315751.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M26368     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 382661..393143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV131_RS02210 - 382971..383846 (+) 876 WP_114865830.1 substrate-binding domain-containing protein -
  DV131_RS02215 pstC 383964..384827 (+) 864 WP_000165887.1 phosphate ABC transporter permease subunit PstC -
  DV131_RS02220 pstA 384820..385635 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  DV131_RS02225 pstB 385637..386389 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  DV131_RS02230 phoU 386404..387054 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  DV131_RS02235 - 387116..387538 (+) 423 Protein_384 transposase -
  DV131_RS02240 comR 387661..388143 (-) 483 WP_240315751.1 helix-turn-helix transcriptional regulator Regulator
  DV131_RS02245 - 388313..389329 (+) 1017 WP_000415108.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  DV131_RS02250 galU 389351..390250 (+) 900 WP_000202229.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  DV131_RS02255 - 390317..390994 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  DV131_RS02260 - 390978..391517 (-) 540 WP_000834308.1 5-formyltetrahydrofolate cyclo-ligase -
  DV131_RS02265 - 391529..392659 (-) 1131 WP_114865832.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 19131.05 Da        Isoelectric Point: 5.0076

>NTDB_id=263122 DV131_RS02240 WP_240315751.1 387661..388143(-) (comR) [Streptococcus pneumoniae strain M26368]
MLIIEVNNSGSSCRLREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPTLTKLKYIAERLGVEDYKLMPS
YIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 483 bp        

>NTDB_id=263122 DV131_RS02240 WP_240315751.1 387661..388143(-) (comR) [Streptococcus pneumoniae strain M26368]
ATGCTTATAATAGAGGTAAACAACTCAGGAAGTTCTTGTAGGTTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTT
GGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATG
GAGAATCCAGACCAACACTAACAAAGTTAAAATATATTGCTGAACGTTTGGGGGTTGAAGATTACAAGTTGATGCCAAGT
TATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGATGAAACTATCGC
CCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAAGATTTATCATCC
CAAATTATTCATATCTAGCACTAGCGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGG
TGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(86-133)

Helix-turn-helix (HTH_3)

(22-73)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

55.833

75

0.419
  comR Streptococcus pyogenes MGAS315

54.167

75

0.406
  comR Streptococcus mutans UA159

54.167

75

0.406
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

54.545

68.75

0.375